- Review Article
- Endocrinology
- Catch-up growth and catch-up fat in children born small for gestational age
- Won Kyoung Cho, Byung-Kyu Suh
- Clin Exp Pediatr. 2016;59(1):1-7. Published online January 22, 2016
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Infants born small for gestational age (SGA) are at increased risk of perinatal morbidity, persistent short stature, and metabolic alterations in later life. Recent studies have focused on the association between birth weight (BW) and later body composition. Some reports suggest that fetal nutrition, as reflected by BW, may have an inverse programing effect on abdominal adiposity later in life....
- Original Articles
- Nephrology (Genitourinary)
- Impaired angiogenesis in the enalapril-treated neonatal rat kidney
- Hyung Eun Yim, Kee Hwan Yoo, Eun Soo Bae, Young Sook Hong, Joo Won Lee
- Clin Exp Pediatr. 2016;59(1):8-15. Published online January 22, 2016
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Purpose Nephrogenesis is normally accompanied by a tightly regulated and efficient vascularization. We investigated the effect of angiotensin II inhibition on angiogenesis in the developing rat kidney.
Methods Newborn rat pups were treated with enalapril (30 mg/kg/day) or vehicle (control) for 7 days after birth. Renal histological changes were checked using Hematoxylin & Eosin staining. We also investigated the intrarenal expression of vascular...
- Genetics and Metabolism
- Identification of 1p36 deletion syndrome in patients with facial dysmorphism and developmental delay
- Go Hun Seo, Ja Hye Kim, Ja Hyang Cho, Gu-Hwan Kim, Eul-Ju Seo, Beom Hee Lee, Jin-Ho Choi, Han-Wook Yoo
- Clin Exp Pediatr. 2016;59(1):16-23. Published online January 22, 2016
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Purpose The 1p36 deletion syndrome is a microdeletion syndrome characterized by developmental delays/intellectual disability, craniofacial dysmorphism, and other congenital anomalies. To date, many cases of this syndrome have been reported worldwide. However, cases with this syndrome have not been reported in Korean populations anywhere. This study was performed to report the clinical and molecular characteristics of five Korean patients with the...
- Neurology
- Factors associated with mumps meningitis and the possible impact of vaccination
- Kyuyol Rhie, Heung-Keun Park, Young-Soo Kim, Jung Sook Yeom, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Chan-Hoo Park, Hyang-Ok Woo, Hee-Shang Youn
- Clin Exp Pediatr. 2016;59(1):24-29. Published online January 22, 2016
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Purpose Mumps meningitis is a common complication of mumps infection; however, information on mumps meningitis in the postvaccine era is limited. The purpose of the present study was to determine factors associated with mumps meningitis and to discuss the effect of vaccination on this disease.
Methods We retrospectively reviewed patients younger than 19 years with mumps, diagnosed at a university hospital in Korea...
- Neonatology (Perinatology)
- Clinical features of Bednar's aphthae in infants
- Seung-Woo Nam, Seol Hee Ahn, Son-Moon Shin, Goun Jeong
- Clin Exp Pediatr. 2016;59(1):30-34. Published online January 22, 2016
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Purpose Although Bednar's aphthae are common and regress spontaneously, these lesions may lead to feeding intolerance and are often misdiagnosed, rendering examinations useless. This study sheds new light on the clinical features of Bednar's aphthae.
Methods Sixteen neonates and infants were newly diagnosed with Bednar's aphthae via routine health check-ups in an outpatient clinic. Medical records were retrospectively reviewed, and the following parameters...
- Neurology
- Intravenous levetiracetam versus phenobarbital in children with status epilepticus or acute repetitive seizures
- Yun-Jeong Lee, Mi-Sun Yum, Eun-Hee Kim, Tae-Sung Ko
- Clin Exp Pediatr. 2016;59(1):35-39. Published online January 22, 2016
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Purpose This study compared the efficacy and tolerability of intravenous (i.v.) phenobarbital (PHB) and i.v. levetiracetam (LEV) in children with status epilepticus (SE) or acute repetitive seizure (ARS).
Methods The medical records of children (age range, 1 month to 15 years) treated with i.v. PHB or LEV for SE or ARS at our single tertiary center were retrospectively reviewed. Seizure termination was defined...
- Case Reports
- Oncology
- Early onset of colorectal cancer in a 13-year-old girl with Lynch syndrome
- Do Hee Ahn, Jung Hee Rho, Hann Tchah, In-Sang Jeon
- Clin Exp Pediatr. 2016;59(1):40-42. Published online January 22, 2016
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Lynch syndrome is the most common inherited colon cancer syndrome. Patients with Lynch syndrome develop a range of cancers including colorectal cancer (CRC) and carry a mutation on one of the mismatched repair (MMR) genes. Although CRC usually occurs after the fourth decade in patients with Lynch syndrome harboring a heterozygous MMR gene mutation, it can occur in children with...
- Infection
- Tuberculosis-associated hemophagocytic lymphohistiocytosis in adolescent diagnosed by polymerase chain reaction
- Ju-Hee Seo, Jun Ah Lee, Dong Ho Kim, Joongbum Cho, Jung Sub Lim
- Clin Exp Pediatr. 2016;59(1):43-46. Published online January 22, 2016
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We present a case of tuberculosis-associated hemophagocytic lymphohistiocytosis in a 14-year-old girl. The patient presented with weight loss, malaise, fatigue, prolonged fever, and generalized lymphadenopathy. Laboratory investigation revealed pancytopenia (white blood cells, 2,020 cells/µL; hemoglobin, 10.2 g/dL; platelets, 52,000 cells/µL), hypertriglyceridemia (229 mg/dL), and hyperferritinemia (1,420 ng/mL). Bone marrow biopsy showed a hypocellular bone marrow with a large numbers of...
