Article 57(11); Nov 2014
Review Articles
Current issues of pediatric inflammatory bowel disease in Korea
Seak Hee Oh, Kyung Mo Kim
Clin Exp Pediatr. 2014;57(11):465-471.   Published online November 30, 2014

Inflammatory bowel disease (IBD) is a chronic relapsing disorder of unknown etiology, which is believed to be multifactorial. Recently, the incidence of pediatric IBD has steeply increased in Korea since 2000. Poorly controlled disease activity can result in complications such as intestinal fistulae, abscess, and stricture, as well as growth retardation and delayed puberty in children. Because of a lack...

Vascular health late after Kawasaki disease: implications for accelerated atherosclerosis
Yiu-Fai Cheung
Clin Exp Pediatr. 2014;57(11):472-478.   Published online November 30, 2014

Kawasaki disease (KD), an acute vasculitis that primarily affects young children, is the most common acquired paediatric cardiovascular disease in developed countries. While sequelae of arterial inflammation in the acute phase of KD are well documented, its late effects on vascular health are increasingly unveiled. Late vascular dysfunction is characterized by structural alterations and functional impairment in term of arterial...

Original Articles
A comparison of the efficacy of amoxicillin and nasal irrigation in treatment of acute sinusitis in children
Abolfazl Khoshdel, Gholam Reza Panahande, Mohamad Kazem Noorbakhsh, Mohamad Reza Malek Ahmadi, Masoud Lotfizadeh, Neda Parvin
Clin Exp Pediatr. 2014;57(11):479-483.   Published online November 30, 2014
Purpose

The efficacy of antibiotic therapy for acute sinusitis is controversial. This study aimed to compare the efficacies of amoxicillin with nasal irrigation and nasal irrigation alone for acute sinusitis in children.

Methods

This randomized, double-blind, controlled study included 80 children aged 4-15 years with a clinical presentation of acute sinusitis. Patients were randomly assigned to receive either amoxicillin (80 mg/kg/day) in 3...

Effect of adenotonsillar hypertrophy on right ventricle function in children
Jin Hwan Lee, Jung Min Yoon, Jae Woo Lim, Kyung Og Ko, Seong Jun Choi, Jong-Yeup Kim, Eun Jung Cheon
Clin Exp Pediatr. 2014;57(11):484-488.   Published online November 30, 2014
Purpose

Chronic upper airway obstruction causes hypoxemic pulmonary vasoconstriction, which may lead to right ventricle (RV) dysfunction. Adenotonsillar hypertrophy (ATH) is the most common cause of upper airway obstruction in children. Therefore, we aimed to evaluate RV function in children with ATH.

Methods

Twenty-one children (male/female, 15/6; mean age, 92.3¡¾39.0 months; age range, 4-15 years) with ATH and 21 healthy age- and gender-matched...

Clinical features and short-term outcomes of pediatric acute fulminant myocarditis in a single center
Eun Young Lee, Hae Lyoung Lee, Hyung Tae Kim, Hyoung Doo Lee, Ji Ae Park
Clin Exp Pediatr. 2014;57(11):489-495.   Published online November 30, 2014
Purpose

The aims of this study were to document our single-center experience with pediatric acute fulminant myocarditis (AFM) and to investigate its clinical features and short-term outcomes.

Methods

We performed a retrospective chart review of all children <18 years old who were diagnosed with AFM between October 2008 and February 2013. Data about patient demographics, initial symptoms, investigation results, management, and outcomes between...

Case Reports
Wernicke's encephalopathy in a child with high dose thiamine therapy
So Won Park, Yoon Young Yi, Jung Woo Han, Heung Dong Kim, Joon Soo Lee, Hoon-Chul Kang
Clin Exp Pediatr. 2014;57(11):496-499.   Published online November 30, 2014

Wernicke's encephalopathy is an acute neurological disorder characterized by mental confusion, oculomotor dysfunction, and ataxia. It has been reported in individuals with alcohol dependence, hyperemesis gravidarum, and prolonged parenteral nutrition without vitamin supplementation. Here we present the case of a 13-year-old male patient with neuroblastoma and a history of poor oral intake and nausea for 3 months. After admission, he...

Multifocal kaposiform hemangioendothelioma of soft tissue with bilateral pulmonary involvement in an adolescent
Roxana Azma, Samin Alavi, Maliheh Khoddami, Mohammad Taghi Arzanian, Armin Nourmohammad, Sadaf Esteghamati
Clin Exp Pediatr. 2014;57(11):500-504.   Published online November 30, 2014

Kaposiform hemangioendothelioma (KHE) is a rare, locally aggressive vascular tumor of intermediate malignancy with resemblance to Kaposi sarcoma. It occurs predominantly in pediatric age groups as a cutaneous lesion with focal infiltration into the adjacent soft tissue and bone. Although visceral involvement is very uncommon, several cases with bone, retroperitoneal, or mediastinal involvement have been described. KHE has been reported...


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