- Review Article
- Nephrology (Genitourinary)
- Atypical hemolytic uremic syndrome and eculizumab therapy in children
- Seong Heon Kim, Hye Young Kim, Su Young Kim
- Clin Exp Pediatr. 2018;61(2):37-42. Published online February 28, 2018
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Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing
Escherichia coli -associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is...
- Original Articles
- Cardiology
- Discrimination of Kawasaki disease with concomitant adenoviral detection differentiating from isolated adenoviral infection
- Jong Han Kim, Hye Ree Kang, Su Yeong Kim, Ji-Eun Ban
- Clin Exp Pediatr. 2018;61(2):43-48. Published online February 28, 2018
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Purpose Human adenovirus infection mimics Kawasaki disease (KD) but can be detected in KD patients. The aim of this study was to determine the clinical differences between KD with adenovirus infection and only adenoviral infection and to identify biomarkers for prediction of adenovirus-positive KD from isolated adenoviral infection.
Methods A total of 147 patients with isolated adenovirus were identified by quantitative polymerase chain...
- Infection
- Treatment-failure tularemia in children
- Arzu Karlı, Gülnar Şensoy, Şule Paksu, Muhammet Furkan Korkmaz, Ömer Ertuğrul, Rıfat Karlı
- Clin Exp Pediatr. 2018;61(2):49-52. Published online February 28, 2018
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Purpose Tularemia is an infection caused by
Francisella tularensis . Its diagnosis and treatment may be difficult in many cases. The aim of this study was to evaluate treatment modalities for pediatric tularemia patients who do not respond to medical treatment.Methods A single-center, retrospective study was performed. A total of 19 children with oropharyngeal tularemia were included.
Results Before diagnosis, the duration of symptoms in...
- Oncology
- Excellent treatment outcomes in children younger than 18 months with stage 4
MYCN nonamplified neuroblastoma - Chiwoo Kim, Young Bae Choi, Ji Won Lee, Keon Hee Yoo, Ki Woong Sung, Hong Hoe Koo
- Clin Exp Pediatr. 2018;61(2):53-58. Published online February 28, 2018
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Purpose Although the prognosis is generally good in patients with intermediate-risk neuroblastoma, no consensus has been reached on the ideal treatment regimen. This study analyzed treatment outcomes and toxicities in patients younger than 18 months with stage 4
MYCN nonamplified neuroblastoma.Methods We retrospectively analyzed 20 patients younger than 18 months newly diagnosed with stage 4
MYCN nonamplified neuroblastoma between January 2009 and...
- Cardiology
- Cardiac function associated with home ventilator care in Duchenne muscular dystrophy
- Sangheun Lee, Heeyoung Lee, Lucy Youngmin Eun, Seung Woong Gang
- Clin Exp Pediatr. 2018;61(2):59-63. Published online February 28, 2018
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Purpose Cardiomyopathy is becoming the leading cause of death in patients with Duchenne muscular dystrophy because mechanically assisted lung ventilation and assisted coughing have helped resolve respiratory complications. To clarify cardiopulmonary function, we compared cardiac function between the home ventilator-assisted and non-ventilator-assisted groups.
Methods We retrospectively reviewed patients with Duchenne muscular dystrophy from January 2010 to March 2016 at Gangnam Severance Hospital. Demographic...
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DOI: https://doi.org/10.3345/kjp.2018.61.2.59 Correction in: Clin Exp Pediatr 2019;62(6):244
- Case Report
- Neurology
- Mild encephalopathy with a reversible splenial lesion in a girl with acute pyelonephritis
- Jung Sook Yeom, Chung Mo Koo, Ji Sook Park, Ji-Hyun Seo, Eun Sil Park, Jae-Young Lim, Hyang-Ok Woo, Hee-Shang Youn
- Clin Exp Pediatr. 2018;61(2):64-67. Published online February 28, 2018
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We report the case of a 12-year-old girl who had mild encephalopathy with a reversible splenial lesion (MERS) associated with acutepyelonephritis caused by
Escherichia coli . The patient was admitted with a high fever, and she was diagnosed with acute pyelonephritis based on pyuria and the results of urine culture, which detected cefotaxime-sensitiveE. coli . Although intravenous cefotaxime and tobramycin were...
- Letter to the Editor
- Neonatology (Perinatology)
- B-type natriuretic peptide may have a role in the management of patent ductus arteriosus
- Jang Hoon Lee
- Clin Exp Pediatr. 2018;61(2):68-69. Published online February 28, 2018
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