- Review Article
- Infection
- Central line-associated bloodstream infections in neonates
- Hye Jung Cho, Hye-Kyung Cho
- Clin Exp Pediatr. 2019;62(3):79-84. Published online December 19, 2018
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Newborn infants, including premature infants, are high-risk patients susceptible to various microorganisms. Catheter-related bloodstream infections are the most common type of nosocomial infections in this population. Regular education and training of medical staffs are most important as a preventive strategy for central line-associated bloodstream infections (CLABSIs). Bundle approaches and the use of checklists during the insertion and maintenance of central...
- Original Articles
- Nephrology (Genitourinary)
- Changes in the thyroid hormone profiles in children with nephrotic syndrome
- Sun Hee Jung, Jeong Eun Lee, Woo Yeong Chung
- Clin Exp Pediatr. 2019;62(3):85-89. Published online October 4, 2018
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Purpose: We compared thyroid hormone profiles in children with nephrotic syndrome (NS) during the nephrotic phase and after remission. Methods: This study included 31 pediatric NS patients. The thyroid hormone profiles included serum levels of triiodothyronine (T3), thyroxine (T4), thyroid-stimulating hormone (TSH), and free T4. Results: Of the 31 patients, 16 (51.6%) showed abnormal thyroid hormone profiles: 6 had overt hypothyroidism, 8...
- Other
- Rapidly growing pediatric trampoline-related injuries in Korea: a 10-year single center retrospective study
- Min Jeng Cho, Jihoon Kim, Sung Jeep Kim, Kyu Hyouck Kyoung, Min Ae Keum, Sung Kyun Park
- Clin Exp Pediatr. 2019;62(3):90-94. Published online March 11, 2019
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Purpose: Several published policy statements have warned against the risks associated with trampoline use and recommended safety guidelines. However, few studies have focused on trampoline-related injuries in Korea. This study aimed to assess the incidence and characteristics of pediatric trampoline-related injuries presented to Ulsan University Hospital. Methods: We retrospectively reviewed the medical records of children aged <16 years with trampoline-related injuries...
- Cardiology
- Changes of Bax, Bcl-2, CCR-2, MCP-1, and TGF-β1 genes in the left ventricle of spontaneously hypertensive rat after losartan treatment
- Hyeryon Lee, Kwan Chang Kim, Young Mi Hong
- Clin Exp Pediatr. 2019;62(3):95-101. Published online October 24, 2018
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Purpose: Increased apoptosis was recently found in the hypertrophied left ventricle of spontaneously hypertensive rats (SHRs). Although the available evidence suggests that apoptosis can be induced in cardiac cells by various insults including pressure overload, cardiac apoptosis appears to result from an exaggerated local production of angiotensin in adult SHRs. Altered expressions of Bcl associated X (Bax), Bcl-2, chemokine receptor...
- Neonatology (Perinatology)
- Iron status in small for gestational age and appropriate for gestational age infants at birth
- Hyeon A Kim, Sook-Hyun Park, Eun Joo Lee
- Clin Exp Pediatr. 2019;62(3):102-107. Published online October 24, 2018
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Purpose: This study compared the iron statuses of small for gestational age (SGA) and appropriate for gestational age (AGA) infants at birth. Methods: The clinical data of 904 newborn infants admitted to the neonatal intensive care unit were reviewed. Blood samples were drawn from the infants within 24 hours after birth. Serum ferritin level was used as a marker of total...
- Case Report
- Neurology
- A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years
- Minsun Kwak, Hye-Ryun Yeh, Mi-Sun Yum, Hyun-Jin Kim, Su Jeong You, Tae-Sung Ko
- Clin Exp Pediatr. 2019;62(3):108-112. Published online September 18, 2018
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Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of 10 years. Interferon-alpha (IFN-α) is a protein that exerts its antiviral activity via enhancement of cellular immune response and is reported to be an effective drug for the treatment of...
