- Review Article
- Neurology
- Cognitive impairment in childhood onset epilepsy: up-to-date information about its causes
- Eun-Hee Kim, Tae-Sung Ko
- Clin Exp Pediatr. 2016;59(4):155-164. Published online April 30, 2016
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Cognitive impairment associated with childhood-onset epilepsy is an important consequence in the developing brain owing to its negative effects on neurodevelopmental and social outcomes. While the cause of cognitive impairment in epilepsy appears to be multifactorial, epilepsy-related factors such as type of epilepsy and underlying etiology, age at onset, frequency of seizures, duration of epilepsy, and its treatment are considered...
- Original Articles
- Neonatology (Perinatology)
- Modification of nutrition strategy for improvement of postnatal growth in very low birth weight infants
- Ah Young Choi, Yong Wook Lee, Mea-young Chang
- Clin Exp Pediatr. 2016;59(4):165-173. Published online April 30, 2016
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Purpose To identify the effects of modified parenteral nutrition (PN) and enteral nutrition (EN) regimens on the growth of very low birth weight (VLBW) infants.
Methods The study included VLBW infants weighing <1,500 g, admitted to Chungnam National University Hospital between October 2010 and April 2014, who were alive at the time of discharge. Subjects were divided according to 3 periods: period 1...
- Cardiology
- Usefulness of anterior uveitis as an additional tool for diagnosing incomplete Kawasaki disease
- Kyu Jin Lee, Hyo Jin Kim, Min Jae Kim, Ji Hong Yoon, Eun Jung Lee, Jae Young Lee, Jin Hee Oh, Soon Ju Lee, Kyung Yil Lee, Ji Whan Han
- Clin Exp Pediatr. 2016;59(4):174-177. Published online April 30, 2016
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Purpose There are no specific tests for diagnosing Kawasaki disease (KD). Additional diagnostic criteria are needed to prevent the delayed diagnosis of incomplete Kawasaki disease (IKD). This study compared the frequency of coronary artery lesions (CALs) in IKD patients with and without anterior uveitis (AU) and elucidated whether the finding of AU supported the diagnosis of IKD.
Methods This study enrolled patients diagnosed...
- Prediction of nonresponsiveness to medium-dose intravenous immunoglobulin (1 g/kg) treatment: an effective and safe schedule of acute treatment for Kawasaki disease
- Kyung Pil Moon, Beom Joon Kim, Kyu Jin Lee, Jin Hee Oh, Ji Whan Han, Kyung Yil Lee, Soon Ju Lee
- Clin Exp Pediatr. 2016;59(4):178-182. Published online April 30, 2016
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Purpose Medium-dose (1 g/kg) intravenous immunoglobulin (IVIG) is effective in the majority of patients with Kawasaki disease (KD) but some patients who do not respond to medium-dose IVIG are at high risk for the development of coronary artery lesions (CALs). The purpose of this study was to identify the clinical predictors associated with unresponsiveness to medium-dose IVIG and the development of...
- Correlation of B-type natriuretic peptide levels and echocardiographic parameters in preterm infants with patent ductus arteriosus
- Hyun Ah Jeong, Jeonghee Shin, Eunji Kim, Eun Hee Lee, Byung Min Choi, Chang Sung Son, Joo Won Lee
- Clin Exp Pediatr. 2016;59(4):183-189. Published online April 30, 2016
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Purpose This study aimed to evaluate the correlation, according to postnatal age, between plasma B-type natriuretic peptide (BNP) levels and echocardiographic parameters for the assessment of patent ductus arteriosus (PDA) in preterm infants with respiratory distress.
Methods We enrolled 42 preterm infants with respiratory distress who underwent serial echocardiographic evaluation with simultaneous plasma BNP measurements until ductal closure. The correlations between BNP levels...
- Subclinical left ventricular dysfunction in children after hematopoietic stem cell transplantation for severe aplastic anemia: a case control study using speckle tracking echocardiography
- Beom Joon Kim, Kyung Pil Moon, Ji-Hong Yoon, Eun-Jung Lee, Jae Young Lee, Seong Koo Kim, Jae Wook Lee, Nack Gyun Chung, Bin Cho, Hack Ki Kim
- Clin Exp Pediatr. 2016;59(4):190-195. Published online April 30, 2016
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Purpose Severe aplastic anemia (SAA), a fatal disease, requires multiple transfusion, immunosuppressive therapy, and finally, hematopoietic stem cell transplantation (HSCT) as the definitive treatment. We hypothesized that iron overloading associated with multiple transfusions and HSCTrelated complications may adversely affect cardiac function. Left ventricular (LV) function was assessed in children after HSCT for SAA.
Methods Forty-six consecutive patients with a median age of 9.8...
- Case Reports
- Immunology
- Concomitant use of corticosteroid and antimicrobials for liver abscesses in patients with chronic granulomatous disease
- Kyung-Sue Shin, Mu Suk Lee
- Clin Exp Pediatr. 2016;59(4):196-201. Published online April 30, 2016
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Chronic granulomatous disease (CGD) is a rare inherited disorder caused by defective nicotinamide adenine dinucleotide phosphate oxidase enzyme and characterized by recurrent bacterial and fungal infections. Although liver abscess is a common manifestation of CGD, its management in CGD patients is not well-defined. In addition, the generalized guidelines for treating liver abscesses do not necessarily apply to CGD patients. Corticosteroids...
- Nephrology (Genitourinary)
- Deficiency of antidiuretic hormone: a rare cause of massive polyuria after kidney transplantation
- Kyung Mi Jang, Young Soo Sohn, Young Ju Hwang, Bong Seok Choi, Min Hyun Cho
- Clin Exp Pediatr. 2016;59(4):202-204. Published online April 30, 2016
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A 15-year-old boy, who was diagnosed with Alport syndrome and end-stage renal disease, received a renal transplant from a living-related donor. On postoperative day 1, his daily urine output was 10,000 mL despite normal graft function. His laboratory findings including urine, serum osmolality, and antidiuretic hormone levels showed signs similar to central diabetes insipidus, so he was administered desmopressin acetate...
