- Review Article
- Nephrology (Genitourinary)
- Pathogenesis of minimal change nephrotic syndrome: an immunological concept
- Seong Heon Kim, Se Jin Park, Kyoung Hee Han, Andreas Kronbichler, Moin A. Saleem, Jun Oh, Beom Jin Lim, Jae Il Shin
- Clin Exp Pediatr. 2016;59(5):205-211. Published online May 31, 2016
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Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia. Minimal change nephrotic syndrome (MCNS) is the most common form of INS in children. The pathogenesis of MCNS still remains unclear, however, several hypotheses have been recently proposed. For several decades, MCNS has been considered a T-cell disorder, which causes the impairment of the glomerular filtration barrier...
- Original Articles
- Neurology
- Clinical features and prognostic factors in drowning children: a regional experience
- Kyung Lae Son, Su Kyeong Hwang, Hee Joung Choi
- Clin Exp Pediatr. 2016;59(5):212-217. Published online May 31, 2016
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Purpose This study aimed to evaluate the clinical features of children who have survived a water submersion incident, and to identify risk factors for prognosis.
Methods We retrospectively reviewed the medical records of patients who experienced submersion between January 2005 and December 2014. The patients were classified into 2 groups, according to complications, and prognostic factors were evaluated.
Results During the study period, 29 children...
- Allergy
- The relationships among birth season, sunlight exposure during infancy, and allergic disease
- Jung Min Hwang, Se Hyun Oh, Mee Yong Shin
- Clin Exp Pediatr. 2016;59(5):218-225. Published online May 31, 2016
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Purpose The recent increase in the prevalence of allergic diseases is hypothetically attributed to immune dysregulation in turn caused by a reduction in exposure to sunlight. We explored relationships between birth season, sunlight exposure, exercise duration, and an allergic disease.
Methods We performed a questionnaire-based survey on allergic diseases among elementary school students. Birth time was categorized according to the season (summer and...
- Gastroenterology
- Efficacy of proton pump inhibitors and H2 blocker in the treatment of symptomatic gastroesophageal reflux disease in infants
- Hamid Reza Azizollahi, Mandana Rafeey
- Clin Exp Pediatr. 2016;59(5):226-230. Published online May 31, 2016
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Purpose Gastroesophageal reflux disease (GERD) occurs in pediatric patients when reflux of gastric contents presents with troublesome symptoms. The present study compared the effects of omeprazole and ranitidine for the treatment of symptomatic GERD in infants of 2-12 months.
Methods This study was a clinical randomized double-blind trial and parallel-group comparison of omeprazole and ranitidine performed at Children Training Hospital in Tabriz, Iran....
- Endocrinology
- Lipopolysaccharide-binding protein plasma levels as a biomarker of obesity-related insulin resistance in adolescents
- Ki Eun Kim, Young Sun Cho, Kyung Suk Baek, Lan Li, Kwang-Hyun Baek, Jung Hyun Kim, Ho-Seong Kim, Youn Ho Sheen
- Clin Exp Pediatr. 2016;59(5):231-238. Published online May 31, 2016
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Purpose Lipopolysaccharide-binding protein (LBP) is a 65-kDa acute phase protein, derived from the liver, which is present in high concentrations in plasma. Data regarding the association between circulating plasma LBP levels and obesity-related biomarkers in the pediatric population are scarce. We aimed to determine whether there was a difference in plasma LBP levels between overweight/obese and normal-weight adolescents and to assess...
- Case Reports
- Gastroenterology
- A giant choledochal cyst in infancy: a case report
- Nursel Yurttutan, Suleyman Cuneyt Karakus, Naim Koku, Mustafa Demirci, Ramazan Ucak
- Clin Exp Pediatr. 2016;59(5):239-241. Published online May 31, 2016
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Choledochal cyst is a dilation that encloses the intrahepatic or both extra- and intrahepatic portions of the biliary ducts. Postnatally, ultrasonography is the initial diagnostic modality of choice, allowing for precise measurements of intra- or extrahepatic duct dilatation and identification of stones and sludge. Symptoms depend on the age at presentation. Common bile duct malformations should be considered as a...
- Nephrology (Genitourinary)
- Bilateral iliac and popliteal arterial thrombosis in a child with focal segmental glomerulosclerosis
- Kyoung Hee Han, Ji Youn Park, Seung-Kee Min, Il-Soo Ha, Hae Il Cheong, Hee Gyung Kang
- Clin Exp Pediatr. 2016;59(5):242-245. Published online May 31, 2016
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Thromboembolic complications (TECs) are clinically important sequelae of nephrotic syndrome (NS). The incidence of TECs in children is approximately 2%–5%. The veins are the most commonly affected sites, particularly the deep veins in the legs, the inferior vena cava, the superior vena cava, and the renal veins. Arterial thrombosis, which is less common, typically occurs in the cerebral, pulmonary, and...
