- Review Articles
- Neurology
- Genetic tests by next-generation sequencing in children with developmental delay and/or intellectual disability
- Ji Yoon Han, In Goo Lee
- Clin Exp Pediatr. 2020;63(6):195-202. Published online November 4, 2019
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Developments in next-generation sequencing (NGS) techogies have assisted in clarifying the diagnosis and treatment of developmental delay/intellectual disability (DD/ID) via molecular genetic testing. Advances in DNA sequencing technology have not only allowed the evolution of targeted panels but also, and more currently enabled genome-wide analyses to progress from research era to clinical practice. Broad acceptance of accuracy- guided targeted gene...
- Allergy
- Drug Allergy in Children: What Should We Know?
- Ji Soo Park, Dong In Suh
- Clin Exp Pediatr. 2020;63(6):203-210. Published online November 12, 2019
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The drug allergy “label” may have a lifetime of consequences for a child. Many children with alleged drug allergies are proven to be tolerant to the culprit medication when challenged. The field of drug hypersensitivity is a recently evolving field of research, but studies on its epidemiology and diagnostic tools are lacking in children. Clinical history is significant in the...
- Editorials
- Neurology
- Next-generation sequencing is a powerful method to enhance diagnostic yield in global developmental delay/intellectual disability
- Jon Soo Kim
- Clin Exp Pediatr. 2020;63(6):211-212. Published online June 11, 2020
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- Allergy
- Are you sure that it is a drug allergy?
- Eun Hee Chung
- Clin Exp Pediatr. 2020;63(6):213-214. Published online June 1, 2020
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- Neonatology (Perinatology)
- What do we know about the long-term cognitive and behavioral outcomes of school-aged children who were born moderate to late preterm?
- Eun Sun Kim
- Clin Exp Pediatr. 2020;63(6):215-216. Published online February 5, 2020
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- Should we regularly evaluate the neurodevelopmental status of moderate and late preterm infants?
- Son Moon Shin
- Clin Exp Pediatr. 2020;63(6):217-218. Published online June 11, 2020
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- Original Articles
- Neonatology (Perinatology)
- Long-term cognitive, executive, and behavioral outcomes of moderate and late preterm at school age
- Ju Hyun Jin, Shin Won Yoon, Jungeun Song, Seong Woo Kim, Hee Jung Chung
- Clin Exp Pediatr. 2020;63(6):219-225. Published online September 25, 2019
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Question: Infants born at moderate to late preterm gestations are known to have little problem later on, but is that really true?
Finding: At school age, cognitive problem was observed in about a quarter of the children. In addition, more than half of the children was suspected of having attention problems.
Meaning: Moderate to late preterm infants are at risk of developing abnormal intelligence and attention problems at early school age, therefore they should not be neglected on longterm follow-up evaluation.
- Synbiotics use for preventing sepsis and necrotizing enterocolitis in very low birth weight neonates: a randomized controlled trial
- Ozge Serce Pehlevan, Derya Benzer, Tugba Gursoy, Guner Karatekin, Fahri Ovali
- Clin Exp Pediatr. 2020;63(6):226-231. Published online February 5, 2020
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Background: Probiotics and prebiotics have strain-specific effects on the host. Synbiotics, a mixture of probiotics and prebiotics, are proposed to have more beneficial effects on the host than either agent has alone.
Purpose: We performed a randomized controlled trial to investigate the effect of Lactobacillus and Bifidobacterium together with oligosaccharides and lactoferrin on the development of necrotizing enterocolitis (NEC) or sepsis...
- General Pediatrics
- Ability of children to perform touchscreen gestures and follow prompting techniques when using mobile apps
- Savita Yadav, Pinaki Chakraborty, Arshia Kaul, Pooja, Bhavya Gupta, Anchal Garg
- Clin Exp Pediatr. 2020;63(6):232-236. Published online February 5, 2020
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Background: Children today get access to smartphones at an early age. However, their ability to use mobile apps has not yet been studied in detail.
Purpose: This study aimed to assess the ability of children aged 2–8 years to perform touchscreen gestures and follow prompting techniques, i.e., ways apps provide instructions on how to use them. Methods: We developed one mobile app...