- Review Articles
- The role of cytokines in seizures: interleukin (IL)-1β, IL-1Ra, IL-8, and IL-10
- Youngah Youn, In Kyung Sung, In Goo Lee
- Clin Exp Pediatr. 2013;56(7):271-274. Published online July 19, 2013
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Brain insults, including neurotrauma, infection, and perinatal injuries such as hypoxic ischemic encephalopathy, generate inflammation in the brain. These inflammatory cascades induce a wide spectrum of cytokines, which can cause neuron degeneration, have neurotoxic effects on brain tissue, and lead to the development of seizures, even if they are subclinical and occur at birth. Cytokines are secreted by the glial...
- Temporal lobe epilepsy surgery in children versus adults: from etiologies to outcomes
- Yun-Jin Lee, Joon Soo Lee
- Clin Exp Pediatr. 2013;56(7):275-281. Published online July 19, 2013
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Temporal lobe epilepsy (TLE) is the most common type of medically intractable epilepsy in adults and children, and mesial temporal sclerosis is the most common underlying cause of TLE. Unlike in the case of adults, TLE in infants and young children often has etiologies other than mesial temporal sclerosis, such as tumors, cortical dysplasia, trauma, and vascular malformations. Differences in...
- Original Articles
- Intravenous fluid prescription practices among pediatric residents in Korea
- Jiwon M. Lee, Younghwa Jung, Se Eun Lee, Jun Ho Lee, Kee Hyuck Kim, Ja Wook Koo, Young Seo Park, Hae Il Cheong, Il-Soo Ha, Yong Choi, Hee Gyung Kang
- Clin Exp Pediatr. 2013;56(7):282-285. Published online July 19, 2013
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Purpose Recent studies have established the association between hypotonic fluids administration and hospital-acquired hyponatremia in children. The present paper investigated the pattern of current practice in intravenous fluid prescription among Korean pediatric residents, to underscore the need for updated education.
Methods A survey-based analysis was carried out. Pediatric residents at six university hospitals in Korea completed a survey consisting of four questions. Each...
- Antibody response to pneumococcal vaccination in children with chronic or recurrent rhinosinusitis
- Ji Hyeon Baek, Hyun Kyong Seo, Hye Mi Jee, Youn Ho Shin, Man Yong Han, Eun Sang Oh, Hyun Ju Lee, Kyung Hyo Kim
- Clin Exp Pediatr. 2013;56(7):286-290. Published online July 19, 2013
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Purpose Although chronic and recurrent rhinosinusitis is prevalent in children, little is known about its causes. Here, we investigated the humoral immunity in children with chronic or recurrent rhinosinusitis.
Methods We examined 16 children attending the outpatient clinic at the CHA Bundang Medical Center including 11 boys and 5 girls, aged 3.11 years (mean age, 5.6 years), who had rhinosinusitis for >3 months...
- Effects of coagulation factor concentrate prophylaxis in moderate and severe hemophilia A patients at a single hemophilia center in Korea
- Byung Suk Moon, Jun Seok Choi, Chur Woo You
- Clin Exp Pediatr. 2013;56(7):291-297. Published online July 19, 2013
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Purpose The aim of this study was to investigate prophylactic treatment effects in Korean patients with severe hemophilia A.
Methods A prospective study of 32 severe hemophilia A patients was conducted with the approval of the Institutional Review Board at the Eulji University Hospital. Two patients received primary prophylaxis; whereas, the other 30 patients were divided into 2 groups-secondary prophylaxis (n=15) and on-demand...
- Risk factors for short term thyroid dysfunction after hematopoietic stem cell transplantation in children
- You Jin Jung, Yeon Jin Jeon, Won Kyoung Cho, Jae Wook Lee, Nack-Gyun Chung, Min Ho Jung, Bin Cho, Byung-Kyu Suh
- Clin Exp Pediatr. 2013;56(7):298-303. Published online July 19, 2013
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Purpose The purpose of this study was to evaluate short-term thyroid dysfunction and related risk factors in pediatric patients who underwent hematopoietic stem cell transplantation (HSCT) during childhood.
Methods We studied 166 patients (100 boys and 66 girls) who underwent HSCT at the Catholic HSCT Center from January 2004 through December 2009. The mean age at HSCT was 10.0±4.8 years. Thyroid function of...
- Case Reports
- Polyclonal gammopathy related to renal bleeding in a peritoneal dialysis patient
- Eun-Mi Cho, Hye-Hyun Moon, Young-Ju Hwang, Seung-Jin Lee, Cheol Woo Ko, Min Hyun Cho
- Clin Exp Pediatr. 2013;56(7):304-307. Published online July 19, 2013
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Polyclonal gammopathy represents the diffuse activation of B cells and is usually related to inflammation or immune-related diseases. However, the mechanisms leading to polyclonal gammopathy are essentially speculative. Generally, infectious, inflammatory, or various other reactive processes may be indicated by the presence of a broad-based peak or band in the gamma region on serum protein electrophoresis results. A 15-year-old girl,...
- Severe hypermagnesemia presenting with abnormal electrocardiographic findings similar to those of hyperkalemia in a child undergoing peritoneal dialysis
- Won Kyoung Jhang, Yoon Jung Lee, Young A Kim, Seong Jong Park, Young Seo Park
- Clin Exp Pediatr. 2013;56(7):308-311. Published online July 19, 2013
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In this report, we present a pediatric case of severe symptomatic hypermagnesemia resulting from the use of magnesium oxide as a laxative in a child undergoing continuous cyclic peritoneal dialysis for end-stage renal disease. The patient showed abnormal electrocardiography (ECG) findings, such as tall T waves, a widened QRS complex, and irregular conduction, which were initially misdiagnosed as hyperkalemia; later,...
