- Review Article
- Nephrotic syndrome: what's new, what's hot?
- Hee Gyung Kang, Hae Il Cheong
- Clin Exp Pediatr. 2015;58(8):275-282. Published online August 21, 2015
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While the incidence of nephrotic syndrome (NS) is decreasing in Korea, the morbidity of difficult-to-treat NS is significant. Efforts to minimize treatment toxicity showed that prolonged treatment after an initial treatment for 2-3 months with glucocorticosteroids was not effective in reducing frequent relapses. For steroid-dependent NS, rituximab, a monoclonal antibody against the CD20 antigen on B cells, was proven to...
- Original Articles
- Iron and vitamin D status in breastfed infants and their mothers
- Yu Sun Kang, Joon Hwan Kim, Eun Hee Ahn, Eun-Gyong Yoo, Moon Kyu Kim
- Clin Exp Pediatr. 2015;58(8):283-287. Published online August 21, 2015
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Purpose We assessed the relationships between iron and vitamin D statuses in breastfed infants and their mothers and evaluated the determinants of iron and vitamin D deficiencies in breastfed infants.
Methods Seventy breastfed infants aged 4-24 months and their mothers participated in this study from February 2012 to May 2013. Complete blood counts, total iron binding capacity, and levels of C-reactive protein, iron,...
- Comparison of gastric and other bowel perforations in preterm infants: a review of 20 years' experience in a single institution
- Do Kyung Lee, So Yeon Shim, Su Jin Cho, Eun Ae Park, Sun Wha Lee
- Clin Exp Pediatr. 2015;58(8):288-293. Published online August 21, 2015
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Purpose In this study, we aimed to review the clinical presentation of preterm infants with gastrointestinal perforations and compare the clinical features of gastric perforation with other intestinal perforations.
Methods The medical records of preterm neonates with pneumoperitoneum, admitted to the neonatal intensive care unit (NICU) between January 1994 and December 2013, were retrospectively reviewed.
Results Twenty-one preterm infants underwent exploratory laparotomy to investigate the...
- Usefulness of pelvic ultrasonography for the diagnosis of central precocious puberty in girls
- Jung Yu, Ha Young Shin, Sun Hee Lee, You Sung Kim, Jae Hyun Kim
- Clin Exp Pediatr. 2015;58(8):294-300. Published online August 21, 2015
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Purpose It is difficult to differentiate between central precocious puberty (CPP) and premature thelarche (PT) in girls. The aim of this study was to investigate the diagnostic usefulness of pelvic ultrasonography to distinguish between CPP and PT in girls with early breast development.
Methods This study included girls with early breast development who visited the clinic between January 2012 and December 2013. Clinical,...
- Evaluation of three glucometers for whole blood glucose measurements at the point of care in preterm or low-birth-weight infants
- Joon Ho Hwang, Yong-Hak Sohn, Seong-Sil Chang, Seung Yeon Kim
- Clin Exp Pediatr. 2015;58(8):301-308. Published online August 21, 2015
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Purpose We evaluated three blood glucose self-monitoring for measuring whole blood glucose levels in preterm and low-birth-weight infants.
Methods Between December 1, 2012 and March 31, 2013, 230 blood samples were collected from 50 newborns, who weighed, ≤2,300 g or were ≤36 weeks old, in the the neonatal intensive care unit of Eulji University Hospital. Three blood glucose self-monitoring (A: Precision Pcx, Abbott;...
- Case Reports
- Successful sulfonylurea treatment in a patient with permanent neonatal diabetes mellitus with a novel
KCNJ11 mutation - Sung Yeon Ahn, Gu-Hwan Kim, Han-Wook Yoo
- Clin Exp Pediatr. 2015;58(8):309-312. Published online August 21, 2015
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Permanent neonatal diabetes mellitus refers to diabetes that occurs before the age of 6 months and persists through life. It is a rare disorder affecting one in 0.2-0.5 million live births. Mutations in the gene
KCNJ11 , encoding the subunit Kir6.2, and ABCC8, encoding SUR1 of the ATP-sensitive potassium (KATP) channel, are the most common causes of permanent neonatal diabetes mellitus....
De novo interstitial deletion of 15q22q23 with global developmental delay and hypotonia: the first Korean case- Ha-Su Kim, Jin-Yeong Han, Myo-Jing Kim
- Clin Exp Pediatr. 2015;58(8):313-316. Published online August 21, 2015
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Interstitial deletions involving the chromosome band 15q22q24 are very rare and only nine cases have been previously reported. Here, we report on a 12-day-old patient with a
de novo 15q22q23 interstitial deletion. He was born by elective cesarean section with a birth weight of 3,120 g at 41.3-week gestation. He presented with hypotonia, sensory and neural hearing loss, dysmorphism with...
