- Review Article
- Neonatology (Perinatology)
- Update of minimally invasive surfactant therapy
- Gyu-Hong Shim
- Clin Exp Pediatr. 2017;60(9):273-281. Published online September 21, 2017
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To date, preterm infants with respiratory distress syndrome (RDS) after birth have been managed with a combination of endotracheal intubation, surfactant instillation, and mechanical ventilation. It is now recognized that noninvasive ventilation (NIV) such as nasal continuous positive airway pressure (CPAP) in preterm infants is a reasonable alternative to elective intubation after birth. Recently, a meta-analysis of large controlled trials...
- Original Articles
- Developmental and Behavioral Medicine
- Application of array comparative genomic hybridization in Korean children under 6 years old with global developmental delay
- Kyung Yeon Lee, Eunsim Shin
- Clin Exp Pediatr. 2017;60(9):282-289. Published online September 21, 2017
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Purpose Recent advancements in molecular techniques have greatly contributed to the discovery of genetic causes of unexplained developmental delay. Here, we describe the results of array comparative genomic hybridization (CGH) and the clinical features of 27 patients with global developmental delay.
Methods We included 27 children who fulfilled the following criteria: Korean children under 6 years with global developmental delay; children who had...
- Allergy
- Accuracy of maximal expiratory flow-volume curve curvilinearity and fractional exhaled nitric oxide for detection of children with atopic asthma
- Sang Hoo Park, Min Ji Im, Sang-Yong Eom, Youn-Soo Hahn
- Clin Exp Pediatr. 2017;60(9):290-295. Published online September 21, 2017
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Purpose Airway pathology in children with atopic asthma can be reflected by the concave shape of the maximal expiratory flow-volume (MEFV) curve and high fractional exhaled nitric oxide (FeNO) values. We evaluated the capacity of the curvilinearity of the MEFV curve, FeNO, and their combination to distinguish subjects with atopic asthma from healthy individuals.
Methods FeNO and angle β, which characterizes the general...
- Pulmonology
- Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus
- Da Eun Roh, Sook-Hyun Park, Hee Joung Choi, Yeo Hyang Kim
- Clin Exp Pediatr. 2017;60(9):296-301. Published online September 21, 2017
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Purpose The aim of this study was to evaluate whether infants with rhinovirus (RV) infection-induced wheezing and those with respiratory syncytial virus (RSV) infection-induced wheezing have different cytokine profiles in the acute stage.
Methods Of the infants with lower respiratory tract infection (LRTI) between September 2011 and May 2012, 88 were confirmed using reverse transcription polymerase chain reaction and hospitalized. Systemic interferon-gamma (IFN-γ),...
- Neurology
- Serum neuron specific enolase is increased in pediatric acute encephalitis syndrome
- Dian Pratamastuti, Prastiya Indra Gunawan, Darto Saharso
- Clin Exp Pediatr. 2017;60(9):302-306. Published online September 21, 2017
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Purpose This study aimed to investigate whether serum neuron-specific enolase (NSE) was expressed in acute encephalitis syndrome (AES) that causes neuronal damage in children.
Methods This prospective observational study was conducted in the pediatric neurology ward of Soetomo Hospital. Cases of AES with ages ranging from 1 month to 12 years were included. Cases that were categorized as simple and complex febrile seizures...
