- Review Articles
- Allergy
- Phenotypes of allergic diseases in children and their application in clinical situations
- Eun Lee, Soo-Jong Hong
- Clin Exp Pediatr. 2019;62(9):325-333. Published online April 23, 2019
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Allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, are common heterogeneous diseases that encompass diverse phenotypes and different pathogeneses. Phenotype studies of allergic diseases can facilitate the identification of risk factors and their underlying pathophysiology, resulting in the application of more effective treatment, selection of better treatment responses, and prediction of prognosis for each phenotype. In the early phase...
- Cardiology
- Understanding the importance of cerebrovascular involvement in Kawasaki disease
- Jung Sook Yeom, Jae Young Cho, Hyang-Ok Woo
- Clin Exp Pediatr. 2019;62(9):334-339. Published online May 16, 2019
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Kawasaki disease (KD) is a systemic vasculitis in infants and young children. However, its natural history has not been fully elucidated because the first case was reported in the late 1960s and patients who have recovered are just now entering middle age. Nevertheless, much evidence has raised concerns regarding the subclinical vascular changes that occur in post-KD patients. KD research...
- Editorials
- Allergy
- Should partially hydrolyzed infant formula be given to the general infant population for the primary prevention of allergic disease?
- Tae Won Song
- Clin Exp Pediatr. 2019;62(9):340-341. Published online May 17, 2019
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- Is determining nasal eosinophil count and nasal eosinophil peroxidase concentration clinically useful in children with rhinits?
- Bong Seok Choi
- Clin Exp Pediatr. 2019;62(9):342-343. Published online July 9, 2019
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- Original Articles
- Nutrition
- The effect of high fat dietary modification and nutritional status on the outcome of critically ill ventilated children: single-center study
- Nehal Mohamed El Koofy, Hanaa Ibrahim Rady, Shrouk Moataz Abdallah, Hafez Mahmoud Bazaraa, Walaa Ahmed Rabie, Ahmed Ali El-Ayadi
- Clin Exp Pediatr. 2019;62(9):344-352. Published online April 2, 2019
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Background: Ventilator dependency constitutes a major problem in the intensive care setting. Malnutrition is considered a major determinant of extubation failure, however, attention has been attracted to modulating carbon dioxide production through decreasing carbohydrate loading and increasing the percent of fat in enteral feeds. The detected interrelation between substrate oxidation and ventilation outcome became the base of several research to...
- Allergy
- Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis
- Yeonu Choi, Haeun Jeon, Eun Ae Yang, Jong-Seo Yoon, Hyun Hee Kim
- Clin Exp Pediatr. 2019;62(9):353-359. Published online April 24, 2019
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Background: Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic cutoff values of EPO for use as a one-time test for allergic diseases such as allergic rhinitis have not been established.
Purpose: To identify the correlation...
- Developmental and Behavioral Medicine
- Effect of omega-3 plus methylphenidate as an alternative therapy to reduce attention deficit-hyperactivity disorder in children
- Soleiman Mohammadzadeh, Narmin Baghi, Fayegh Yousefi, Bahar Yousefzamani
- Clin Exp Pediatr. 2019;62(9):360-366. Published online May 20, 2019
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Background: Attention deficit-hyperactivity disorder (ADHD) is one of the most common chronic behavioral disorders in school-aged children.
Purpose: This study aimed to evaluate the effect of omega-3 supplementation as an alternative therapy for ADHD, which can be caused by vitamin and mineral deficiencies. Methods: This was a double-blinded clinical trial study. Sixty-six children with ADHD (aged 6–12 years) referred to our child...
