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Letter to the Editor
Gastroenterology
Pediatric abdominal ultrasound training program for pediatricians
Soon Chul Kim
Clin Exp Pediatr. 2024;67(9):474-476.   Published online August 20, 2024
Hematology
Neutropenia following metamizole use in pediatric patients: a multicenter retrospective study
Meraj Alam Siddiqui, Arzu Akyay, Fatma Burcu Belen Apak, Özgür Carti, Canan Albayrak, Melek İşik, Zühre Kaya, Sevgi Yetgin, Lale Olcay
Clin Exp Pediatr. 2024;67(8):415-417.   Published online July 23, 2024
Developmental and Behavioral Medicine
Efficacy of social skills group intervention among children with mild autism spectrum disorder
Lee Ling Low, Ker Yang Chua, Bih Hwa Ching
Clin Exp Pediatr. 2024;67(7):368-370.   Published online May 31, 2024
Neonatology (Perinatology)
Pentraxin 3 as a marker of early-onset neonatal sepsis
Safaa ELMeneza, Iman El-Bagoury, Hind Rayes, Amira Hassan
Clin Exp Pediatr. 2024;67(6):312-314.   Published online May 23, 2024
Assessment of iron status and red cell parameters in healthy term small for gestational age neonates at birth
Arif Hossain, Shorna Rahman, Shahana Akter, Ismat Jahan, Sanjoy Kumer Dey, Abdul Mannan, Mohammod Shahidullah
Clin Exp Pediatr. 2024;67(4):221-223.   Published online March 19, 2024
Pulmonology
Metabolic syndrome and pulmonary dysfunction in asthmatic children during the COVID-19 pandemic
Jue Seong Lee, Sang Hyun Park, Yoon Lee, Seunghyun Kim, Wonsuck Yoon, Young Yoo
Clin Exp Pediatr. 2024;67(3):168-170.   Published online February 19, 2024
General Pediatrics
Vitamin B12 deficiency in anemic children before versus after age 2 years: a form of hidden hunger in India
Sahil Goel, Ruchika Bhatnagar, Anita Kumari, Brig Prem Lochan Prasad, Lahar Sahai
Clin Exp Pediatr. 2024;67(2):116-118.   Published online January 24, 2024
Neonatology (Perinatology)
Association between feeding intolerance and intestinal dysbiosis in very premature infants
Putri Maharani Tristanita Marsubrin, Agus Firmansyah, Rinawati Rohsiswatmo, Zakiudin Munasir, Saptawati Bardosono, Safarina G. Malik, Yuditiya Purwosunu, Ina S. Timan, Tetty Yuniati, Maya Yulindhini
Clin Exp Pediatr. 2023;66(11):501-503.   Published online October 24, 2023
Allergy
Increased serum eosinophilic cationic protein in children with nonspecific chronic cough
Young Hwan Kim, Yoon Young Jang, Jieun Jeong, Hai Lee Chung
Clin Exp Pediatr. 2023;66(10):455-457.   Published online September 14, 2023
Infection
SARS-CoV-2 fecal shedding pattern in pediatric patients with acute COVID-19 or COVID-19-associated multisystem inflammatory syndrome
Setareh Mamishi, Fatemeh Jalali, Sepideh Benvari, Babak Pourakbari, Mohammad Reza Abdolsalehi, Reihaneh Hosseinpour Sadeghi, Mohammad Shahbabaie, Amene Navaeian, Shima Mahmoudi
Clin Exp Pediatr. 2023;66(8):366-368.   Published online June 14, 2023
Chest x-ray findings in children with COVID-19: lesson learned from referral hospitals in Medan, North Sumatera, Indonesia
Andrew Limavady, Eka Airlangga, Ririe Fachrina Malisie, Ayodhia Pitaloka Pasaribu
Clin Exp Pediatr. 2023;66(7):317-319.   Published online May 16, 2023
Developmental and Behavioral Medicine
Effect of rolling over pattern and caregiver perception on plagiocephaly in Korean infants
Jin A Yoon, Soo-Yeon Kim, Yong Beom Shin
Clin Exp Pediatr. 2023;66(6):272-273.   Published online May 24, 2023
Endocrinology
Accuracy of predicted adult height using the Greulich-Pyle method and artificial intelligence medical device
Dongho Cho, Yun Sun Choi, Hayun Oh, Young min Ahn, Ji-Young Seo
Clin Exp Pediatr. 2023;66(3):145-147.   Published online January 25, 2023
Critical Care Medicine
Role of serum bilirubin-to-albumin ratio as a prognostic index in critically ill children
You Min Kang, Ga Eun Kim, Mireu Park, Jong Deok Kim, Min Jung Kim, Yoon Hee Kim, Kyung Won Kim, Myung Hyun Son, Soo Yeon Kim
Clin Exp Pediatr. 2023;66(2):85-87.   Published online December 5, 2022
Cardiology
Early prophylaxis of cardiomyopathy with beta-blockers and angiotensin receptor blockers in patients with Duchenne muscular dystrophy
Heirim Lee, Jinyoung Song, I-Seok Kang, June Huh, Jin A Yoon, Yong Beom Shin
Clin Exp Pediatr. 2022;65(10):507-509.   Published online August 22, 2022
Developmental and Behavioral Medicine
The influence of parental eating behaviors, child-feeding practices, and infants’ temperaments upon infants’ eating behaviors
Goh Woon Lim, Kyoung Min Shin
Clin Exp Pediatr. 2022;65(9):466-468.   Published online June 27, 2022
Infection
Changes in epidemiology of parainfluenza virus and respiratory syncytial virus infection during coronavirus disease 2019 pandemic in Korea
Kyung-Ran Kim, Hwanhee Park, Doo Ri Kim, Yae-Jean Kim
Clin Exp Pediatr. 2022;65(6):320-321.   Published online March 10, 2022
Question: How the epidemiology of other childhood respiratory viruses has changed during coronavirus disease 2019 (COVID-19) in Korea?
Finding: Parainfluenza virus (PIV) typically circulated in the spring, and respiratory syncytial virus (RSV) epidemic started in autumn in Korea before COVID-19 pandemic. PIV and RSV seasons disappeared in 2020 and came back in 2021 with atypical seasonality. PIV season was changed from spring to autumn, and the beginning of RSV season was slightly delayed from autumn to early winter in 2021.
Meaning: Circulation of PIV and RSV was changed to unusual seasons and patterns during COVID-19 pandemic period.
Neonatology (Perinatology)
Telemedicine as progressive treatment approach for neonatal jaundice due to the coronavirus disease 2019 pandemic
Sukanya Sudhir Joshi, Bithiah Roy Benroy, Isabell Nelson Lawrence, Thanuja Jayasri Suresh
Clin Exp Pediatr. 2022;65(5):269-271.   Published online February 7, 2022
Question: How can the management of neonatal jaundice (NJ) be enhanced through telemedicine?
Finding: Teleconsultations, drive-through testing, and the use of an application to assess neonatal jaundice at home are being successfully used, but they must be further researched before being implemented on a larger scale.
Meaning: Recent technology allows for the treatment of NJ at home with an application that helps reduce hospital burden.
Other
Changes in air pollution and childhood respiratory viral infections in Korea post-COVID-19 outbreak
Hyung Kyu Park, Jung Yeon Shim
Clin Exp Pediatr. 2022;65(4):211-213.   Published online February 17, 2022
Oncology
Retrospective review of severe acute respiratory syndrome coronavirus-2 infection in children with acute leukemia from a tertiary care hospital in Northern India
Suhail Chhabra, Aditya Dabas, Richa Mittal, Neha Goel, Ritabrata Roy Chowdhary, Satyendra Batra, Amitabh Singh, Rani Gera
Clin Exp Pediatr. 2022;65(3):150-151.   Published online November 26, 2021
Other
Evaluation of simulation-based ultrasound course for pediatricians: a starting point for future training curriculum
Chon In Kuok, Avis Siu Ha Leung, Jonan Chun Yin Lee, Winnie Kwai Yu Chan
Clin Exp Pediatr. 2022;65(1):53-55.   Published online July 28, 2021
Question: Simulation-based ultrasound training is becoming more popular. Is there a role for pediatricians in such training programs?
Finding: Our program received promising feedback from its participants. Self-rated confidence in image interpretation and ultrasound-guided catheter insertion improved after the simulation. Participants reported a higher preference for performing ultrasound scans before radiologist assessment.
Meaning: Ultrasound training can be considered as part of the pediatric training curriculum in the future.
Allergy
Environmental and dietary factors to be checked for treatment of atopic dermatitis in rural children
Sanghwa Youm, Eunjoo Lee, Jeongmin Lee
Clin Exp Pediatr. 2021;64(12):661-663.   Published online October 1, 2021
Question: What are the distinctive features of rural children with atopic dermatitis?
Finding: Birch and dog dander were the second most sensitized aeroallergens (32.6%), followed by house dust mites. Doctors and guardians reported food allergy comorbidities differently (19.9% and 43.5%, respectively). Dietary restrictions without medical evaluation were observed in 39.7% of patients.
Meaning: Effects of pollen distribution and indirect animal exposure should be evaluated. Evidence-based dietary restrictions must be implemented.
Infection
Multisystem inflammatory syndrome in children and Kawasaki disease in infants: 2 sides of the same coin?
Hing Cheong Kok, Dinesh Nair, Ke Juin Wong, Siew Moy Fong
Clin Exp Pediatr. 2021;64(11):599-601.   Published online October 7, 2021
Question: Are multisystem inflammatory syndrome in children (MIS-C) and Kawasaki disease (KD) in infants, 2 sides of the same coin?
Finding: Here we report on a 4-month-old girl with MIS-C and signs of KD with shock. Most (83%) infants with MIS-C had features of KD, especially KD shock syndrome.
Meaning: MIS-C is similar to KD, and likely is a consequence of dysregulated immune responses secondary to sudden acute respiratory syndrome coronavirus 2 infection.
Gastroenterology
Functional gastrointestinal disorders and smartphone use in adolescents
Mauro Cinquetti, Marco Biasin, Marco Ventimiglia, Linda Balanzoni, Denise Signorelli, Angelo Pietrobelli
Clin Exp Pediatr. 2021;64(9):494-496.   Published online November 9, 2020
Question: Are functional gastrointestinal disorders (FGIDs) common in Italy? If so, what are the associated risk factors?
Finding: In this cross-sectional study of 1,594 adolescents, the prevalence of FGIDs was 30.9% and was mainly associated with smartphone addiction.
Meaning: Smartphone use and dietary habits should be monitored in children with FGIDs.
General Pediatrics
Skipping breakfast is associated with lifestyle habits among Japanese pupils
Jun Kohyama
Clin Exp Pediatr. 2021;64(8):433-435.   Published online November 4, 2020
Question: Breakfast is important; however, adolescents are increasingly skipping it.
Finding: Skipping breakfast is independently associated with sleepiness, physical inactivity, dinner irregularity, screen time on school days, poor academic performance, after-school activity, and decreased sleep duration before school day.
Meaning: Reducing screen time on school days, after-school activity, and irregular dinner habits might decrease breakfast skipping, resulting in decreased sleepiness and improved academic performance.
Hyperinflammatory syndrome in children during the coronavirus disease 2019 pandemic in sub-Himalayan region
Seema Sharma, Shikha Verma, Isha Bhatia, Ravinder Singh, Mohit Bajaj, Milap Sharma
Clin Exp Pediatr. 2021;64(7):370-372.   Published online May 11, 2021
Question: Is there an increase in patients with hyperinflammatory syndrome during the coronavirus disease 2019 pandemic?
Finding: We found 10 patients with hyperinflammatory syndrome with poor outcome during a period of 2 months in a single tertiary care centre.
Meaning: Pediatricians who come across patients with muco cutaneous manifestations and multiorgan involvement should consider hyperinflammatory syndrome. Early recognition and prompt treatment of such patients may result in promising outcome.
Neonatology (Perinatology)
Role of neutrophil CD11b expression in diagnosis of earlyonset neonatal sepsis in full-term infant
Safaa ELMeneza, Walaa Mohamed, Iman Elbagoury, Karima Bahagat
Clin Exp Pediatr. 2021;64(1):44-45.   Published online April 14, 2020
Question: Can CD11b detect sepsis in full-term infants with suspected sepsis?
Finding: The percentage of neutrophils expressing CD11b was significantly upregulated in the sepsis and suspected sepsis groups versus the control group.
Meaning: CD11b is a sensitive marker for sepsis and suspected sepsis in full-term neonates and it may be added to sepsis markers. This information would allow the neonatologist to confidently discontinue antibiotic use as long as the neonate is clinically stable.
Cardiology
Differences over 10 years in epidemiologic and clinical features of Kawasaki disease at a single tertiary center
Hyun Su Kim, Suk Won Shin, Bo Geum Choi, Hee Joung Choi
Clin Exp Pediatr. 2020;63(4):157-158.   Published online February 5, 2020
General Pediatrics
Effectiveness of comprehensive hand hygiene module on preschool children in Klang Valley, Malaysia
Mohd Dzulkhairi Mohd Rani, Nurul Azmawati Mohamed, Tengku Zetty Maztura Tengku Jamaluddin, Zarini Ismail, Shalinawati Ramli, Habibah Faroque, Farishah Nur Abd Samad, Abdul Rasyid Ariffien, Aisyah Ar Redha Che Amir Farid, Ilina Isahak
Clin Exp Pediatr. 2020;63(3):115-116.   Published online February 5, 2020
Neonatology (Perinatology)
Risk factors for BiPAP failure as an initial management approach in moderate to late preterm infants with respiratory distress
Heekwon Son, Eui Kyung Choi, Kyu Hee Park, Jeong Hee Shin, Byung Min Choi
Clin Exp Pediatr. 2020;63(2):63-65.   Published online February 15, 2020
Question: Which factors can predict BiPAP failure as the initial management approach for moderate to late preterm infants with respiratory distress?
Finding: RDS aggravation and increased oxygen and frequency requirements during BiPAP support were associated with BiPAP failure.
Meaning: Early changes to invasive ventilator care should be considered for moderate to late preterm infants showing RDS aggravation and increased oxygen and frequency requirements during BiPAP support.
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