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Most-cited articles are from the articles published during the last two years (2024 ~ ).

Review Article
Adolescence Medicine
Diet-related behaviors affecting health and substance use among children and adolescents
Ji-Hyun Seo, Sochung Chung
Clin Exp Pediatr. 2024;67(12):664-671.   Published online October 31, 2024
· Diet behaviors in children and adolescents are influenced by environmental and sociocultural factors.
· Unhealthy diet behaviors and poor diet quality are the main contributing factors to noncommunicable diseases and mental health problems during childhood and adolescence.
· Smoking and alcohol drinking in children and adolescents may be associated with unhealthy diet behavior or poor diet quality.
Neonatology (Perinatology)
Strategies to support language development in neonatal intensive care unit: a narrative review
Ju Sun Heo, Ee-Kyung Kim
Clin Exp Pediatr. 2024;67(12):651-663.   Published online November 6, 2024
· Preterm infants often experience speech and language development delays during early childhood, impacting children's ultimate outcomes.
· Promoting breastfeeding, increasing parent-infant interactions in a single-family room, promoting a nurturing language environment by parental book reading and language interventions, and parent-integrated interventions in the neonatal intensive care unit could potentially enhance children's language development.
· Integrating these strategies through family-centered care is essential.
Editorial
Allergy
Comorbidities of allergic rhinitis in children
Yong Ju Lee
Clin Exp Pediatr. 2024;67(12):675-676.   Published online July 31, 2024
· Allergic rhinitis in children often goes undiagnosed or untreated, with significant systemic complications like sleep disorders, growth issues, and gastrointestinal symptoms linked to nasal obstruction.
· A patient-centered action plan that considers symptom severity, preferences, and comprehensive management of associated complications is essential for effective treatment.
Original Article
Allergy
Regional differences in diagnosis and management of cow's milk allergy
Fabian Hendricx, Emma Robert, Jaime A. Ramirez-Mayans, Karen Rubi Ignorosa Arellano, Erick M. Toro Monjaraz, Yvan Vandenplas
Clin Exp Pediatr. 2024;67(11):601-607.   Published online October 28, 2024
· Although there is broad consensus on many aspects regarding the symptoms, diagnosis, and treatment of cow's milk allergy, the impact of geographical, cultural, and socioeconomic factors remains unestablished.
· Availability and cost of formula for the management of cow's milk allergy have a major impact on the therapeutic choice.
· Region-specific guidelines for the treatment of cow's milk allergy are required.
Clinical Note
Immunology
Comparative analysis of rare periodic fever syndromes including the first Korean case of hyperimmunoglobulinemia D and periodic fever syndrome
Yoonsun Yoon, Hyun Seo Kim, Jung Ok Shim, JungHwa Lee
Clin Exp Pediatr. 2024;67(10):550-552.   Published online September 24, 2024
Review Article
Developmental and Behavioral Medicine
Effect of pesticide exposure on stunting incidence: a systematic review and meta-analysis
Sani Rachman Soleman, Yaltafit Abror Jeem, Muhammad Fathi Banna Al Faruqi, Mahdea Kasyiva, Vita Widyasari, Kuswati Kuswati, Nur Aini Djunet, Muflihah Rizkawati, Ety Sari Handayani
Clin Exp Pediatr. 2024;67(10):510-518.   Published online September 24, 2024
This review aimed to determine whether pesticide exposure is associated with stunting in children. The 13 included studies agree that pesticide exposure is not correlated with stunting incidence regardless of substance type (organophosphate and pyrethroid). Heterogeneity appeared with age covariate as potential confounding. The evidence of this study is challeng-ing, as the adverse effects of pesticides grossly occurred. The protection of children is warranted for preventing future neurodevelopment issues.
Original Article
Neonatology (Perinatology)
Protective effect of recombinant interleukin-10 on newborn rat lungs exposed to short-term sublethal hyperoxia
Hyeon-Soo Lee, Young-Joon Ryu, Min-Jae Lee
Clin Exp Pediatr. 2024;67(10):540-549.   Published online September 27, 2024
Lung injury is generated from the early stage of hyperoxia through the biologic effects of cell death and inflammatory response, which eventually leads to evolution of bronchopul-monary dysplasia. Therefore, a protective measure against hyperoxia-induced lung injury is needed. The present study observed that anti-inflammatory cytokine, interleukin-10 had protective effects on newborn rat lungs from injury induced at the early stage of hyperoxia, by preventing cell death and down-regulating inflammatory response.
Editorial
Nephrology (Genitourinary)
Clinical considerations and practical issues of kidney complications in children after COVID-19 infection or vaccination
Jiwon Jung, Joo Hoon Lee
Clin Exp Pediatr. 2024;67(1):35-36.   Published online November 17, 2023
· The proper monitoring for and treatment of coronavirus disease 2019 (COVID-19)-induced acute kidney injury, which is common in critically ill children, are recommended.
· Glomerulopathy associated with COVID-19 or its vaccination has been reported, and the overall clinical course is similar to that of non-COVID-19-associated diseases.
· Additional COVID-19 vaccinations are recommended; however, careful and individualized decisions should be made in patients with COVID-19- or vaccination-associated glomerulopathy.


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