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Chronic granulomatous disease is characterized by an inability of patients* leukocytes to
generate hydrogen peroxide and to kill non-peroxide forming bacteria, such as staphylococci,
E. coli and serratiae etc.
We experienced a case of chronic granulomatous disease with recurrent pyogenic infection.
It was diagnosed by clinical findings and laboratory examinations including NBT test. Clin-
ical findings showed persistent diarrhea since birth, recurrent bacterial pneumonia, perianal
abscess,... |