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Original Article

Neuroprotective effects of resveratrol via anti-apoptosis on hypoxic-ischemic brain injury in neonatal rats

Jin Young Shin, Min Ae Seo, Eun Jin Choi, Jin Kyung Kim, Eok Su Seo, Jun Hwa Lee, Hai Lee Chung, Woo Taek Kim

Clin Exp Pediatr. 2008;51(10):1102-1111. Published online October 15, 2008

Purpose : Resveratrol, extracted from red wine and grapes, has an anti-cancer effect, an antiinflammatory effect, and an antioxidative effect mainly in heart disease and also has neuroprotective effects in the adult animal model. No studies for neuroprotective effects during the neonatal periods have been reported. Therefore, we studied the neuroprotective effect of resveratrol on hypoxic-ischemic brain damage in neonatal...

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