Clinical and Experimental Pediatrics

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Original Article

The Influence of the Use of Iodine during Perinatal Period on the Screening Test for Congenital Hypothyroidism

Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee

Clin Exp Pediatr. 1996;39(2):195-206. Published online February 15, 1996

Purpose : This study was performed to detect the diseases of congenital hypothyroidism by the neonatal mass screening test early and to demonstrate the possible role of topical iodinated antiseptics(povidone-iodine, PVP-Ⅰ) on transient hyperthyrotropinemia in newborn infants. Methods : We performed neonatal screening tests for inborn errors of metabolism since 1985 by Guthrie test for PKU, maple syrup urine disease, histidinemia,...

Two cases of islet cell hyperplasia with nesidioblastosis.

Myeong Ku Cho, Kyeong Bae Park, Gyu Bum Cho, Dong Hwan Lee, Sang Jhoo Lee, D.H Lee

Clin Exp Pediatr. 1991;34(2):273-280. Published online February 28, 1991

Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or adenoma. We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was found, but histology revealed islet cell hyperplasia and nesidioblastosis. After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other showed normal glucose...

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