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Original Article
Immunologic Changes of HL-60 Cells by Differentiation Inducing Agents I : Phenotypic Differentiation of FcγR and Mac-1
Hye Soon Kim, Kyung Hyo Kim, Gyoung Hee Kim, Ju Young Seoh
Clin Exp Pediatr. 1998;41(10):1342-1350.   Published online October 15, 1998
Purpose : Fc receptors and Mac-1 play an important role in the protective response of granulocytes and monocytes against microbial infection. FcγRⅠ, FcγRⅡ, FcγRⅢ as well as CD11b/ CD18 have never been measured in a quantitative way during hemopoiesis. Thus we quantified the expression of FcγRⅠ, FcγRⅡ, FcγRⅢ, and CD11b/CD18 during hematopoietic differentiation using HL-60 cells, which was induced to...
Case Report
Transcatheter Coil Closure of a Congenital Coronary Arterial Fistula
Hye Soon Kim, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Young Soo Yun
Clin Exp Pediatr. 1997;40(5):730-734.   Published online May 15, 1997
Congenital coronary artery fistulas are rare congenital heart anomalies. Surgical closure of these fistulas was the therapy of choice till recently. The recent development of a new accurate coil-delivery system has enabled us to embolize the vessels. Percutaneous transcatheter coil embolization is a safe and effective approach to treating coronary artery fistulas and should be considered as the best treatment...
Original Article
3 Cases of Kawasaki Disease Associated Thrombocytopenia
Hye Soon Kim, Young Mi Hong, Seung Joo Lee
Clin Exp Pediatr. 1995;38(12):1686-1690.   Published online December 15, 1995
Kawasaki disease may be associatde with a variety of hematologic abnormalities, the most characteristic being thrombocytosis. Thrombocytopenia, in contrast, appears to occur rarely in children with this disease. Hera et al observed the 2% manifested thrombocytopenia early in their illness. To our knowledge, early thrombocytopenia has not been reported in other populations, We report the case of a children with...
Clinical Stududy of CATCH 22
Hye Soon Kim, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Young Soo Yun, Jung Sun Kim, Jeong Wook Seo
Clin Exp Pediatr. 1995;38(12):1603-1609.   Published online December 15, 1995
The recognition that deletion of 22ql1 is a common cause of varied malformations and clinical disorders took more than a decade to achieve. Deletions of chromosome 22ql1 have been seen in association with DiGeorge syndrome (DGS) and velo¡ⓒ cardio-facial syndrome (VCFS). The large clinical overlap between DiGeorge syndrome and velo-cardio-facial syndrome suggest an aetiological connection. CATCH 22 synd¡ⓒrome is characterized...
Evaluation of Pulmonary Venous, Mitral and Aortic Flow Pattern by Doppler Echocardiography in Neonates
Hye Soon Kim, Young Mi Hong, Gyoung Hee Kim
Clin Exp Pediatr. 1994;37(5):596-605.   Published online May 15, 1994
Pulmonary vein velocities have recently been estimated in conjunction with mitral flow velocities to increase our understanding of ventricular filling. The advent of transesophageal echocardiography with pulsed doppler imaging capability has provided a method by which both the mitral valve and pulmonary vein velocities can be easily recorded because of the posterior approach providing unimpeded interrogation of cardiac structures. The purpose...
Phenobarbital Dosage and Blood Level for Control of Neonatal Seizure
Hye Soon Kim, Keun Lee, Young Sook Ko
Clin Exp Pediatr. 1993;36(12):1641-1646.   Published online December 15, 1993
Twenty-five neonates was observe for the relationship between phenobrbital loading dose, plasma concentrations and control of seizures. Nineteen neonates (76%) had seizures controlled by phenobarbital alone, Effective plasma concentration were 10.0~31.3㎍/ml. Although 14 neonates had seizures controlled by phenobarbital concentration below 20㎍/ml, neonate required level above 30㎍/ml. We foound that continued benefit was obtained until phenobarbital plasma concentrations reached 40㎍/ml...
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