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Original Article
Plasma Atrial Natriuretic Peptide Concentrations of the Pulmonary artery, Aorta and Veins in Children with Cardiac Disease
Kang Il Lee, Nam Geun Heo, Myung Chul Hyun, Sang Bum Lee, Eun Kyoung Yang, Won Jung Lee
Clin Exp Pediatr. 1994;37(4):481-493.   Published online April 15, 1994
To study the site of release and factors affecting the releases of the atrial natriuretic peptide (ANP) in the pediatric patients, we measured the plasma ANP concentrations in 23 normal healthy children, 19 patients with congestive heart failure and 16 patients with cardiac disease undergoing diagnostic cardiac catheterization. The following results were obtained. 1) The plasma ANP concentrations of the vein (226.3¡¾74.9...
Postnatal Changes of Cretine Kinase and Isoenzyme Activities in Normal and Asphyxiated Newborns
Ki Young Koo, Nam Geun Heo, Heng Mi Kim
Clin Exp Pediatr. 1993;36(9):1219-1226.   Published online September 15, 1993
This study was conducted to evaluate the postnatal changes of serum creatine kinase (CK)and its isoenzymes in normal and asphyxiated newborns. In normal newborns total CK, CK-MM and CK-MB reached a plateau between 2 and 24 hr after birth whereas the serum CK-BB remained stable after birth. CK-MM, CK-MB and CK-BB respectivily composed 90~94%, 5~7% and 1~5%...
Serial Doppler Echocardiographic Evaluation of Anthracycline Induced Left Ventricular Dysfunction in Children
Nam Geun Heo, Myung Chul Hyun, Kun Soo Lee, Sang Bum Lee
Clin Exp Pediatr. 1993;36(2):214-222.   Published online February 15, 1993
Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions. There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances. At the present time it appears that a...
Assessment of Cardiac Output by Doppler Ultrasound Technique Alone.
Young Ho Ahn, Sung Min Choi, Nam Geun Heo, Sang Bum Lee
Clin Exp Pediatr. 1990;33(8):1074-1080.   Published online August 31, 1990
The normal range of ascending aortic blood velocity was determined in 23 healthy children including 8 newborn infants and compared with 12 anemic children, using a pulsed Doppler ultrasound technique from suprasternal long axis view. Integration of the area under the velocity-time curve for each heart beat gave stroke distance, which, when multiplied by heart rate, gave minute distance. Stroke distance and minute distance are...
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