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Original Article
Prolonged Fever in Korean Children: Review of 120 Cases.
Ho Seong Kim, Dong Goo Lee, Dong Soo Kim
Clin Exp Pediatr. 1990;33(11):1516-1525.   Published online November 30, 1990
The authors reviewed the 120 patients with prolonged fever whose temperature was over 38.5°C and of undetermined etiology, who were admitted in Y야isei Medical Center from March 1982 to March 1989. The results were as follows; 1) The children admitted with prolonged fever were 0.3% of total in-patients at the same time. 2) 20 cases were less than 1 year of age on admission and 39...
A Case of Estrogen-producing Sertoli-Leydig Cell Tumor with Precocious puberty.
Myung Sun Oh, Nan Kyoung Kim, Dae Hyun LIm, Jeung Hee Kim, Byong Kwan Son, In Suk Joo, Ku Sang Kim, Young Chai Joo
Clin Exp Pediatr. 1990;33(9):1301-1305.   Published online September 30, 1990
We have experienced a case of estrogen producing Sertoli-Leydig cell tumor with precocious puberty in a 2-year-old girl. Her chief complaints were breast enlargement, which was noticed 20 days prior to admission and vaginal bleeding, which was noticed 10 days prior to admission. The diagnosis was made on the basis of history, physical examination, ultra sonography, hormonal study, and histologic study after operation. She was...
IgA Nephropathy in Childhood.
Yong Choi, Dong Woo Son, Ja Wook Koo, Dong Kyu Jin, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1990;33(9):1237-1243.   Published online September 30, 1990
In this study we compared between the patients with recurrent gross hematuria (group 1, n=45) and * with nephrotic range proteinuria (group 2, n=21) in IgA nephropathy who were admitted to Seoul National University Children’s Hospital during the period from January, 1980 to December, 1989. The results of the study were as follows. 1) Age of onset and sex ratio were not different between the...
A Study of C-Reactive Protein in Acute Infectious Diseases in Children.
H K Choi, Y H Chung
Clin Exp Pediatr. 1990;33(6):762-771.   Published online June 30, 1990
The C-reactive protein is an abnormal protein, which is reacted to various non-specific stmuli such as infection, tissue necrosis, trauma, neoplasm and granuloma formation. Hence, C-reactive protein was index of infection and its allied diseases. Serum C-reactive protein determination on total 207 patients with infectious disease and allied conditions were done in the pediatric ward of Chungnnam National Hospital during the period from Jan, 1988...
A Case of Transient Myeloproliferative Disorder in Down's Syndrome.
Ji Hye Kang, Young Mi Hong, Kyung Hee Kim, Seung Joo Lee, Ki Sook Hong, Ok Kyung Kim, Je Geun Chi
Clin Exp Pediatr. 1990;33(2):252-258.   Published online February 28, 1990
Transient myeloproliferative disorder has been reported in infant with Down's syndrome during neonatal period. This is clinically and hematologically indistinguishable from congenital acute leukemia. In contrast to congenital leukemia, complete clinical and hematological recovery occurs within weeks to months of diagnosis without antileukemic treatment. A neonate presented with jaundice, hepatosplenomegaly and mongoloid face was diagnosed as Transient myeloproliferative disorder. We report this case with a review of...
A Clinical Study of Hereditary Spherocytosis.
Ki Ho Kim, Kun Soo Lee, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1990;33(1):81-87.   Published online January 31, 1990
The following results were obtained from eight cases of hereditary spherocytosis (HS) who were admitted at the Department of Pediatrics, Kyung-pook National University Hospital from July 1984 to January 1989. The percentage of HS among the pediatric hematology patients during the same period was 2.6%. Male amd female were one and seven respectively. The mean age at the diagnosis and at onset of symptom was...
E-Type Prostaglandin Therapy for Neonatal Cyanotic CHD.
Ah Young Yun, Jeong Yeon Choi, Yong Soo Yoon
Clin Exp Pediatr. 1990;33(1):59-65.   Published online January 31, 1990
Between December 1987 and November 1988, Twenty infants with ductus-dependent congenital heart disease received intravenous infusion of PGE1 in the pediatric department of Seoul National University Hospital. Nineteen infants had cyanotic congtenital heart diseases and one had severe coarctation of aorta. Fifteen infants responded to PGE1 treatment and the mean Pa02 increased from 24 mmHg to 40 mmHg within one hour of infusion. Seven infants...
A case of congenital posterior choanal atresia.
Dae Shik Kim, Ran Namgung, Chul Lee, Dong Gwan Han, Seung Kyu Chung
Clin Exp Pediatr. 1989;32(11):1546-1552.   Published online November 30, 1989
The congenital posterior choanal atresia is an uncommon, but not rare, disorder that may threaten the newborn’s existence or give rise to chronic symptoms. As many as 50% of patients with choanal atresia have other associated anomalies. We experienced a case of congenital posterior choanal atresia without associated anomaly in 6 day old female baby. The patient was hospitalized due to the main symptoms...
The clinical evaluation for children with orthostatic proteinuria.
Chan Sung Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1989;32(11):1520-1525.   Published online November 30, 1989
Total of eighteen children with orthostatic proteinuria were evaluated for clinical characteristics. The development of renal or urologic diseases were monitored on these subjects for 1 year. The results were as following; 1) The number of children with transient orthostatic proteinuria and fixed orthostatic proteinuria were 7(39%) and 11(61%), respectively. 2) In children with fixed and reproducible orthostatic proteinuria, mild proteinuria were noted in 73% but no massive...
A case of Idiopathic Crescentic Glomerulonephritis.
Mi Kyung Kim, Hyun Joo Choi, Seung Joo Lee, Ok Kyung Kim
Clin Exp Pediatr. 1989;32(10):1435-1441.   Published online October 31, 1989
Idiopathic crescentic glomerulonephritis is a very rare disease especially in children with poor prognosis. We experienced a case of idiopathic crescentic glomerulonephritis in a 4-year-old male patient who presented initially with a nephrotic syndrome and progressed to a rapidly progressive glomerulonephritis. We review literatures briefly.
Analysis of Asymptomatic Proteinuria in School Children.
Chong Guk Lee, Tae Sub Shim, Dong Hwan Lee, Yong Soo Yun, Chang Jun Ko, Sa Jun Chung, Hyun Soon Lee, Sung Jae Suh, Pyung Nam Kim
Clin Exp Pediatr. 1989;32(9):1187-1194.   Published online September 30, 1989
Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11，14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87...
Clinical Observation and Electroencephalographic Findings relatee to Prognostic factor in Neonatal Seizure.
Soo Chun Kim, Jung Sam Jeon, Chong Woo Bae, Sa Joon Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(6):816-822.   Published online June 30, 1989
To study the clinical prognosis of the neonatal seizure, we carried out a retrospective review on medical records of 40 neonates who were admitted to the Dept. of Pediatrics, Kyung Hee University Hospital between January 1979 and December 1986. The results from the study are summarized as follows 1) Male to female ratio were 1.8:1. In 50.0%(20/40) of newborn infants, neonatal seizure was detected under...
A case of Holoprosencephaly.
Won Chil Lee, In Chae Kim, Kung Min Lee, Chull Zoo Jung, Wang Bok Lee
Clin Exp Pediatr. 1988;31(12):1674-1679.   Published online December 31, 1988
A case of Holoprosencephaly, alobar type in 1-day-old female infant was presented. This patient manifested median facial defects and had extracranial anomaly such as cardiac defects. Chromosome studies showed a normal female karyotype with 46 chromosomes. The diagnosis was confirmed by brain CT scan and autopsy. A brief review of literature was made.
Serum C-Reactive Protein in Differential Diagnosis of Meningitis in Children.
Hae Lim Chung, Hoan Jong Lee, Yong Seung Hwang
Clin Exp Pediatr. 1988;31(12):1588-1593.   Published online December 31, 1988
CSF findings such as cell count, differential count, protein, glucose and serum CRP determined by capillary precipitin method evaluated in 90 patients of meningitis admitted to the pediatric ward of Seoul National University Children’s Hospital, in terms of differential diagnosis of meningitis. The results are as follows; 1) There was considerable overlap of CSF findings and hematQlogic values between bacterial, aseptic and tuberculous meningitis groups. 2) All 9...
Two Cases of Allergic Rhinitis in Children Diagnosed by Youlten's Peak Nasal Inspiratory Flow (PNIF) Meter.
Yil Sub Lee, In Suck Ryu, Kyu Eun Kim, Ki Young Lee
Clin Exp Pediatr. 1988;31(11):1527-1532.   Published online November 30, 1988
Two asthmatic children associated with allergic rhinitis were performed nasal provocation test with various allergens which were detected by allergic skin test. The degree of nasal obstruction induced by allergens were measured with Youlten’s Peak Nasal Inspiratory Flow (PNIF) meter and Red top,Trichophyton and Sagebrush were known as causative allergens in case 1, and Chrysanthemum was detected as causative allergen in case 2. The...
Clinical Evaluation of Children with Psychiatric Problems Among Pediatric Patients.
Woo Tae Kim, Chan Yung Kim
Clin Exp Pediatr. 1988;31(9):1183-1192.   Published online September 30, 1988
The author has analysed 1080 cases of Pediatric patients visited Pediatric or psychiatric depart- ment for behavioral, emotional, or Psychiatric problems, from July 1982 to June 1987. The patients were categorized into three groups to observe the distribution of age, sex and disease, and the relation of symptom and disease, 127 cases consulted to Psychiatric department, 356 cases visited Psychiatric department directly, and 597...
Lipoproteinelectropheresis pattern in Nephrotic Syndrome.
Soon Don Hong, Byung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1988;31(9):1163-1170.   Published online September 30, 1988
This study was undertaken to eluidate lipoprotein patterns in patients with childhood nephrotic syndrome by response to initial steroid therapy, serum albumin level in MCNS and other histologic classifications. The result were summerized as follows. 1) There were 19 cases (52.8%) of abnormal lipoprotein patterns by Fredrickson classifications, type Ila were 6 cases (16.7%), type lib were 1 cases (2.8%) and type IV were 12 cases...
A Case of Iron Deficiency Anemia with Hypoproteinemia.
Seong Ho Kim, Woo Kill Lee
Clin Exp Pediatr. 1988;31(8):1054-1058.   Published online August 31, 1988
Severe iron deficiency anemia is occasionally accompanied by hypoproteinemia and edema. There is evidence that the hypoproteinemia is caused by increased intestinal loss of serum protein. We experienced a case, 1 year and 6 months old female patient with generalized edema, diagnosed as iron deficiency anemia with hypoproteinemia. After treatment with ferrous iron preparation, generalized edema was subsided, and hemoglobin value and serum protein...
A Prospective Study of Urinary beta2 -Microglobulin in Infants with Meconium-Stained Amniotic Fluid.
Sung Oh Kim, Jeh Hoon Shin, Woo Gill Lee, Soo Jee Moon, Keun Soo Lee
Clin Exp Pediatr. 1988;31(8):968-976.   Published online August 31, 1988
We studied prospectively whether events that result in meconium staining may be associated with additional abnormalities that are not clinically apparent associated by measurements of urinary concentrations of β₂-microglobulin indicating renal proximal tubular functions. Among 61 fullterm, healthy neonates delivered at Hanyang University Hospital during the period of September 1986 through April 1987, urinary concentration of β₂-microglobulin and creatinine were measured during the immediate perinatal...
Present status and Problems of weaning.
Young Le Yoon, Moon Hae Bang, Hong Kee Bang, Gang Il Lee, Hak Joo Cha, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1988;31(7):863-872.   Published online July 31, 1988
This study was conducted to find out the present status and problems of weaning in the provinces of Korea with the 578 outpatients who visited Chun-An, Ku-Mi and Eum-Sung Soon Chun Hyang University Hospital from November 1986 to June 1987. The results and problems obtained from the study are summerized as follows 1) Among 578 parents of this study, 173 were from country and 405...
Treatment of Acute Myelogenous Leukemia in Children: Remission Induction with Adriamycin and Cytosine Arabinoside, and Postremission Maintenance Chemotherapy with Adriamycin, Cytosine Arabinoside and 6-thioguanine.
Soon Ki Kim, Hyo Seop Ahn, Chang Yee Hong
Clin Exp Pediatr. 1988;31(7):850-862.   Published online July 31, 1988
The authers assessed the effectiveness of chemotherapy in 40 children with AML, experienced at Seoul National University Children’s Hospital during 8 years 5 months from April 1979 to August 1987. Remission induction treatment included adriamycin 30 mg/m2/day IV on days 1-3 and cytosine arabinoside 75 mg/m2/day continuous IV infusion on days 1-5. This regimen was repeated, if necessary, for one or two more courses. After...
A Case of Myositis Ossificans Progressiva.
Yoeng Ho Ra, Sung Ho Cha, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):271-275.   Published online February 28, 1988
A cases of Myositis ossificans progressiva in a 3 year-old girl who presented with hard mass in her right buttock and progressive hardening of muscles of her back and neck. The diagnosis was made on the basis of typical clinical features and characeristic radiologic findings. In addition to the cases report, a review of related literatures were discussed.
Factors Influencing the Prognosis of Reye Syndrome.
Chang Ho Hong, Heung Dong Kim, Pyung Kil Kim
Clin Exp Pediatr. 1987;30(11):1252-1258.   Published online November 30, 1987
While the etiology of Reye syndrome is still unknown, wide variations in both the clinical spectrum and the therapeutic outcome of patients have been noted. We reviewed the cases of 42 Reye syndrome patients who were admitted to Young Dong Severance Hospital during the period from April, 1983 to July, 1986 and analyzed factors influencing the prognosis of Reye syndrome. The patients were divided...
Clinical Observation and Study for Cerebrospinal Fluid Protein Levels in Aseptic Meningitis.
D H Chee, M I Lee, S H Kim, K C Sohn
Clin Exp Pediatr. 1987;30(10):1107-1114.   Published online October 31, 1987
Observation for clinical findings and laboratory findings, especially for cerebrosipinal fluid protein level has been done in 57 cases of aseptic meningitis who had been admitted to pediatric dept, of National Medical Center from Jan. ’81 to May ’85. The results were as follows; 1) The ratio of male to female was 1.7:1, and the cases were distributed relatively evenly through ...
Syndrome of Inappropriate Secretion of Antidiuretic Hormone(SIADH) in Acute Respiratory Diseases.
Young Jee KIm, Young Yull Koh, Jeong Kee Seo, Hung Ko Moon
Clin Exp Pediatr. 1987;30(9):1021-1028.   Published online September 30, 1987
The SIADH incidence and relevant factors in acute respiratory diseases were evaluated in 461 children with over 28 days old, hospitalized for bronchiolitis, viral pneumonia, bacterial pneumonia, mycoplasma pneumonia and asthma, without other causes of electrolyte imbalance. The overall incidence of SIADH in acute respiratory diseases was 11.93%. The incidence in mycoplasma pneumonia (19.05%) was highest and incidence in bacterial pneumonia (17.42%), viral pneumonia (9.17%),...
Clinical Value of Urinary β₂ -Microglobulin in Patients with Urianry Tract Infection.
Nak Uk Sung, Chang Ryul Kim, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(9):1014-1020.   Published online September 30, 1987
Urinary tract infection (UTI) in children is relatively common infectious disease and it may be the forerunner of severe renal diseases in adulthood. The site of infection is an important factor in the evaluation of the clinical course, treatment and prognosis of patients with UTI, because patients with bacteriuria of renal origin (pyelonephritis) are probably at risk of developing the renal parenchymal reduction seen...
Clinico-Epidemiological Study on Leprosy Patients in Children.
Koo Jeoung Jung, Byoung Soo Cho, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn, Do Seo Koo, Do Il Kim
Clin Exp Pediatr. 1987;30(7):769-776.   Published online July 31, 1987
Clinico-epidemiological study on 44 patients with leprosy in less than 20-year-old children visited to Institute for Leprosy Research, Korean Leprosy Control Association during past 9 years from January, 1978, to August, 1986 was carried out and the following results were obtained. 1) Age at time of visit was shown peak in the age group of 16-20 years (34 cases, 77%), but non in the age...
Case Report
A Case of Holoprosencephaly.
Byung Chun Suh, Soon Sup Jang, In Joon Seol, Soo Jee Moon, Chong Moo Park, Seok Chol Jeon
Clin Exp Pediatr. 1987;30(6):695-700.   Published online June 30, 1987
We experienced a case of holoprosencephaly with extracranial abnormalities, including orbital hypotelorism, median cleft lip without philtrum, flat nasal bridge, flat face, and microcephaly and with a karyotype, 46 XX, 22p+. The diagnosis was confirmed by brain CT scan & brain ultrasonography, and the findings were compatible with an alobar type of holoprosencephaly. The patients died at 26 days of age. A brief review of...
Original Article
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
A Survey of the Outcome of Childhood Asthma.
Hyung Ja Park, Myung Ik Lee, Sun Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1987;30(1):55-63.   Published online January 31, 1987
An outcome of 416 children who was diagnosed and treated for bronchial asthma at pediatric department of National Medical Center from 1965 to 1984 was surveyed using return postcard. The following results were obtained. 1) We mailed 416 cards and 74 cards (17.8%) were returned. 2) 37.8% of the patients had been entirely asymptomatic for a year or more and 32.5% improved. 22.9% of the patients...
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