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Original Article
Clinical Significance of Immature Reticulocyte Fraction and Reticulocyte Cellular Indices in Pediatric Anemia Patients
Young Seo, Hye Lim Jung, Jae Won Shim, Deok Su Kim, Jeong Yeon Shim, Moon Soo Park
Clin Exp Pediatr. 2005;48(3):284-291.   Published online March 15, 2005
Purpose : Flow cytometric automated reticulocyte analysis is a superior method to manual reticulocyte counting, with respect to precision and sensitivity. Furthermore, flow cytometric analysis is able to measure immature reticulocyte fraction(IRF) and reticulocyte cellular indices(RCI : cell hemoglobin content : CHr, mean cell volume : MCVr, cell hemoglobin concentration mean : CHCMr, distribytion width : RDWr, HDWr, CHDWr). In...
Clinical Lecture
Differential Diagnosis and Treatment of Anemia in Children
Young Tak Lim
Clin Exp Pediatr. 2005;48(2):121-125.   Published online February 15, 2005
Anemia can be defined as a reduction in blood hemoglobin concentration or red cell mass relative to age matched normal values. Clinical presentation may range from obviously pale and lethargy to an incidental finding during screening of an otherwise well appearing child. The differential diagnosis of anemia in each instance is broad with numerous possible etiologies. A careful history and...
Original Article
Iron Deficiency Anemia and Iron Nutrition in Adolescent Female Athletes
Yang Kyong Kim, Bo Young Kang, Young Jin Hong, Byong Kwan Son, Kwang Hoi Kim, Soon Ki Kim
Clin Exp Pediatr. 2004;47(10):1041-1046.   Published online October 15, 2004
Purpose : Iron deficiency, particularly iron deficiency anemia(IDA) often not only decreases athletic performance but also impairs immune function and leads to other physiologic dysfunctions. This study was designed to assess and compare iron status and the IDA prevalence in female adolescent athletes with those of general adolescent students. Methods : Physical measurements and hematologic examinations were performed for adolescent...
Nutritional Assessment and the Effectiveness of Dietary Counseling in Infants and Young Children with Iron Deficiency Anemia
Ja Kyoung Kim, Eun Young Ko, Yu Jin Lee, Yong Hun Jun, Soon Ki Kim
Clin Exp Pediatr. 2003;46(1):11-16.   Published online January 15, 2003
Purpose : Iron deficiency is still the most common nutrient deficient disorder despite the improvement in general health and nutrition. This study is designed to evaluate the dietary history of infants and young children with iron deficiency anemia(IDA) and the effects of nutritional counseling. Methods : This study was conducted on 120 children from 6 to 36 months of age with...
Anemia and Serum Iron Status in Adolescent Female
Ju Rae Cho, Soon Ki Kim, Sang Kyu Park, Jeong Ok Hah
Clin Exp Pediatr. 2002;45(3):362-369.   Published online March 15, 2002
Purpose : Anemia is still the most common nutrient deficiency worldwide, especially in adolescence because of an insufficient supply of iron, an increased iron requirement due to accelerated physical growth and blood loss due to menstruation in girls. This study was designed to assess the anemia and serum iron status of middle school girls. Methods : Hematologic examinations, physical examinations and...
Red Blood Cell Indices, Serum Iron and Total Iron Binding Capacity in Children with Helicobacter pylori Infection
Soo Joon Park, Chang Han Lee, Ki Sup Chung
Clin Exp Pediatr. 2000;43(6):755-762.   Published online June 15, 2000
Purpose : H. pylori infection was recently reported to be associated with unexplained iron-deficiency anemia(IDA) in children and adolescents. H. pylori-related IDA was thought to occur due to GI blood loss, scavenging of iron by H. pylori and iron malabsorption. The aim of this study was to examine how the status of H. pylori infection and age of children affected...
A Comparative Study of Red Blood Cell Indices and Anemia by Feeding Patterns
Pill-Jin Shin, Chong-Woo Bae, Yong-Mook Choi
Clin Exp Pediatr. 1999;42(8):1104-1110.   Published online August 15, 1999
Purpose : Iron-deficiency anemia is the most common nutritional deficiency in young infants. This study was designed to determine feeding patterns in infants, and determine a correlation between feeding patterns and incidence of anemia. Methods : This study was conducted by taking blood tests (hemoglobin, hematocrit, and red cell indices) by venipuncture with the electronic counters from 221 infants aged 9-12...
Gastrointestinal Disease in Children with Iron Deficiency Anemia
Yong Joo Kim, Sung Kyun Park, Ho Joon Lim, Hahang Lee
Clin Exp Pediatr. 1999;42(5):697-703.   Published online May 15, 1999
Purpose : The authors performed this study to find out the associated GI disease and H. pylori infection in children with iron-deficiency anemia(IDA). Methods : Twenty-six children older than 2 years with IDA and no history of insufficient iron intake were investigated from 1994 to 1998. Gastrofiberoscopic examination and biopsy and rapid urease test were performed with serum H. pylori IgG....
Clinical Features and Endoscopic Findings of Helicobacter pylori Infection in Children
Seon Hee Kim, Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1998;41(10):1359-1364.   Published online October 15, 1998
Purpose : Helicobacter pylori(H. pylori) is recognized as the cause of primary or unexplained gastrointestinal diseases in children as well as in adults. However, it is unclear whether H. pylori causes specific clinical symptoms or diseases. Therefore, we studied the clinical manifestations associated with H. pylori infection in consecutive symptomatic children undergoing diagnostic endoscopy. Methods : This study included 42...
Milk Feeding Methods and the Changes of Serum Lactate Level in Infants with Iron Deficiency Anemia
Du Young Choi, Jong Duck Kim
Clin Exp Pediatr. 1998;41(4):514-520.   Published online April 15, 1998
Purpose : Infants undergo critical and rapid stages of growth. Optimal nutrition during this period is therefore essential. Iron deficiency is especially impotant and common. The aim of this study was to determine the present status and problems of milk feeding methods in infants with iron deficiency anemia and, futhermore, to develop appropriate feeding guidelines for adequate iron nutrition. Latate is the end product...
The Impact of Prolonged Breast Milk Feeding and Large Amount of Whole Cow's Milk Intake on Iron Status in Early Childhood
Pei Tai Wang, In-sang Jeon
Clin Exp Pediatr. 1998;41(4):437-443.   Published online April 15, 1998
Purpose : The Large amounts of whole cow’s milk intake, just followed by prolonged breast milk feeding may induce a severe deficit of iron. We performed this study to investigate the severity of iron deficiency in these subjects. Methods : Seventy-one subjects(12 to 48 months of age) were classified according to history of prolonged breast milk feeding and intake of large amounts of whole...
Rapid Socio-environmental Changes and Adolescent Problems in Korea
Duk-Jin Yun
Clin Exp Pediatr. 1997;40(10):1360-1375.   Published online October 15, 1997
Purpose : There were rapid socio-environmental changes in Korea caused by industrializations in last thirty years. Those changes are : first, abrupt changes from the environments with closed Confucian ideas to the liberal democratic society, second, agricultural society changed to industrialized society and families with two or three generations are broken down into nuclear families at each generation, third, the annual personal income was...
Case Report
Four Cases of Iron Deficiency Anemia with Helicobacter pylori Infection
Houng Soung, Cheol Ho Chang, Churl Young Chung
Clin Exp Pediatr. 1996;39(8):1173-1178.   Published online August 15, 1996
Helicobacter pylori has become apparent that this organism is an etiologic agent of gastrits and peptic ulcer disease in humans. We present four cases of iron deficiency anemia, not specific causes, in 3 males and 1 female patients with Helicobacter pylori infection, who were treated with antibiotics and iron supplemented therapy. Diagnosis was confirmed by endoscopic biopsies and hematologic findings. A brief review of related...
Original Article
The Correlation between the Duration of Breast Feeding and Iron Deficiency Anemia(IDA)
Yee Ja Kang, Ha Sin Park, Hae Jin Choeh, Kyuchul Choeh
Clin Exp Pediatr. 1995;38(11):1453-1459.   Published online November 15, 1995
Purpose : Iron deficiency anemia(IDA) is the most common nutritional deficiency. in young infants. This study was designed to determine a correlation between the duration of breast feeding and the severity of IDA, and to determine the recommending start point of iron fortified diet. Methods : The correlation between duration of breast feeding, and severity of iron deficiency. and IDA was...
Iron Deficiency Anemia in Infants
Woon Ja Chung, Kue Sook Kim, Mi Kyung Kim, Shin Na Kim
Clin Exp Pediatr. 1995;38(9):1253-1261.   Published online September 15, 1995
Purpose : To study the incidence of iron deficiency anemia we conducted blood tests with questionnaire regrarding weaning status. We tried to figure out the relation between iron deficiency anemia and financial and educational levels of their parents. The purpose of this study is to emphasize the importance of screening for iron deficiency anemia at well baby clinic and educate mothers...
A Study on Nutritional Status of Iron and Lipids in Infants
Kwang-Hea Choi, Son Moon Shin, Kee-Hwa Oh, Jung Sook Seo, Kwang-Soo Kim, Yung-Sun Choi
Clin Exp Pediatr. 1995;38(3):297-305.   Published online March 15, 1995
Purpose : This study was conducted to get baseline data to establish a guideline for the infant nutrition by observing the feeding practice and nutritional intake during infancy and evaluationg the nutritional status of iron and lipids at 12-month-old infants. Methods : This survery was cnducted from July to November, 1992. Subjects were healthy infants who were brought to Yeungnam University...
Case Report
Longterm Follow Up of A Case of Eosinophilic Gastroenteritis
So Young Lee, Jeong Kee Seo
Clin Exp Pediatr. 1995;38(1):104-109.   Published online January 15, 1995
Eosinophilic gastroenteritis(EG) is a rare disease characterised histologically by eosinophilic infiltration of the gut wall. The clinical features depend on which layer and location are involved. Patients may be divided into three clinical groups as predominantly mucosal, muscle layer, or subserosal disease based on the histological site of eosinophilic infiltration of the bowel wall, although there is lften considerable overlap....
Original Article
Study on Iron Deficient State in the Female Adolescent Athletes
Pil Seob Shim, Ja Hyun Park, Dong Gun Park, Kwang Chul Lee, Young Chang Tockgo
Clin Exp Pediatr. 1994;37(7):953-960.   Published online July 15, 1994
Iron deficient state occurs commonly in the athlets, and the cause may be cause may be inadequate iron intake, loss of iron from sweat, blood loss of gastrointestinal tract, and hematuria. The age of the athletes ranged from 11 to 17 years old. I messured red blood cell count, hemoglobin, hematocrit, and related hematologic factors in the 32 adolescent female...
Diagnostic Significance of Red Cell Indices in Non-anemic Iron Deficiency and Iron Deficiency Anemia: Reevaluation with ROC Curve
Hwang Min Kim, Won Kyu Choi, Jae Seung Yang, Jong Soo Kim
Clin Exp Pediatr. 1994;37(1):33-39.   Published online January 15, 1994
To validate the diagnostic significance of red cell indices in non-anemic iron deficiency and iron deficiency anemia, complete blood count, serum iron, total iron binding capacity, and serum ferritin were measured in 208 middle school girls between 13 and 15 years age. We used Reciever Operating Characteristic (ROC) curve to compare the diagnostic significances of various red cell indices (MCV,...
The Impact of Large Amount Whole Cow's Milk Intake on Iron Status in Early Childhood
Sung Yoon Byun, Mi Ran Park, In Sang Jeon
Clin Exp Pediatr. 1993;36(7):968-974.   Published online July 15, 1993
To determine the impact of intake large amount whole cow's milk (WCM) on iron status during early childhood(18~36 months), selected indices of complete blood count (CBC) and iron status were compared between the WCM large amount intake group (n=20) and small amount intake group (n=20). WCM large amount intake children's mean hemoglobin and mean hematocrit were 9.6¡¾1.7g/dl and 30.8¡¾4.5% respectively. These...
A Study on the Relationship between Juvenile Delinquency and Family Environment
Duk Jin Yun, Jung Kyoo Park, Jong Bok Chung, Jung Mo Nam, Jong Yun Park
Clin Exp Pediatr. 1993;36(2):195-207.   Published online February 15, 1993
This study was conducted to find out an appropriate means for preventing the juvenile delinquecy(JD), which is supposed to be greatly realted to family environment. The data were collected through a questionnaire survey with a means of writing by themself, to 257 middle and high school students and 309 juvenile delinquetns who were in confinement. The question-naire was consisted of 27...
The Relationship Between Neonatal Hypoglycemia and Newborn Iron Status in Hypoglycemic Large-for-Gestational Age Infants
Myung Ja Yun, In Ho Song, Hye Lim Jung, Dong Hyuck Kum
Clin Exp Pediatr. 1992;35(12):1667-1673.   Published online December 15, 1992
We assessed the relationship between neonatal hypoglycemia and newborn iron status in hypoglycemic large-for-gestational age, euglycemic large for gestational age and euglycemic appropriate for gestational age infants that were admitted to the department of Pediatrics, Koryo General Hospital from July 1989 to June 1990. The results are as follows; 1) The incidence of large for gestational age infants was 3.3% (32...
HDL Cholesterol, Copper, Ceruloplasmin, Zinc, Iron Values of the Blood in Newborn
Kyeong Sang Kim, Chun Hang Lee, Hong Jin Lee, Won Ill Park, Kyung Ja Lee, Tae Hyon Yoon, Won Chan Tae
Clin Exp Pediatr. 1992;35(8):1096-1101.   Published online August 15, 1992
HDL choleaterol, copper, ceruloplasmin, zinc, and iron values of the blood of 85 newborns delivered at hallym University hospital from September, 1989 to February, 1991 were analysed. The results were as follows: 1) The mean value of HDL cholesterol in 50 normal newborns was 31.37¡¾9.47mg/dl, that of copper 80.54¡¾17.54ug/dl, that of ceruloplasmin 11.34¡¾6.37mg/dl, that of zinc 92.81¡¾79.74ug/dl, that of iron 198.98¡¾86.07 ug/dl. 2)...
Factors which Affect the Serum Ferritin in Whole Cow's Related Iron Deficiency Anemia Children
In Sang Jeon
Clin Exp Pediatr. 1992;35(2):219-225.   Published online February 15, 1992
The adverse effect of introducing whole cow's milk (WCM) into the diet of children are still controversial. Between March 1990 and February 1991 a retrospective study was undertaken to assess the factors which affect the serum ferritin in 20 whole cow's milk related iron deficiency anemia children ,experience at the department of Pediatrics, Chung Goo Sung Sim Hospital. The values...
Whole Cow's milk Related iron Deficiency Anemia in Early Childhood.
In Sang Jeon, Heon Seok Han, Hyo Seop Ahn, Jin Q Kim
Clin Exp Pediatr. 1990;33(10):1374-1379.   Published online October 31, 1990
To study the relationship between large amount of whole cow’s milk (WCM) intake and iron deficiency anemia (IDA) in early childhood, we carried out the study on 9 children with IDA, who were fed WCM, about 1,000 ml over 3 months, experienced at the department of Pediatrics, Seoul National University Hospital, during 5 months from March 1989 to July 1989. The results were as...
Prevalence Study of Anemia among Urban and Rural Middle School Girl Students.
Jeong Ok Hah, Mi Hwa Kang, Jeung Ho Kim
Clin Exp Pediatr. 1990;33(8):1087-1096.   Published online August 31, 1990
This study was conducted to investigate the prevalence rate of anemia and iron deficiency in pubertal girls in urban and rural areas. Venous peripheral blood was sampled from 346 girls who were randomly selected from 1,900 students of one girls’ middle school in Taegu city and all of 311 girls attending two middle schools in rural area, one in Cheungdo county and, another...
Therapeutic Effect of Iron Deficiency Anemia.
Dong Suk Lee, Chang Hee Han, Kun Soo Lee
Clin Exp Pediatr. 1990;33(6):799-806.   Published online June 30, 1990
A prospective study was conducted to see the therapeutic effect of iron deficiency anemia on a different oral iron doses. Studied patients consisted of 48 children with iron deficiency anemia who were admitted to our Pediatric Department during January 1988 - September 1989. Three groups were consisted with Group A (element iron dose 3 mg/kg/d, 16 cases), Group B (3 mg/kg/d with vitamin C...
Severe Iron Deficiency Anemia as a Result of Congenital Hiatal Hernia.
H Y Lee, H G Ham, M K Namgoong, B K Lim, J S Kim
Clin Exp Pediatr. 1989;32(2):250-254.   Published online February 28, 1989
Congenital diaphragmatic anomaly is a rare congenital malformation. A 6 year old boy with pale appearance and complaining of weakness for several months was diagnosed as having iron deficiency anemia as a result of congenital hiatal hernia. The diagnosis was confirmed by chest X.ray, esophagogram, upper gastrointestinal series and bone maπow biopsy After the hernia was successfully corrected by operation, the anemia was disappeared. Congenital...
A Study on Red Cell Distribution Width of Iron Deficiency Anemia in Childhood.
Hong Ryang Kil, Young Hun Chung
Clin Exp Pediatr. 1988;31(10):1321-1327.   Published online October 31, 1988
A hematologic study was undertaken on 60 cases of control group and 53 cases of iron deficiency anemia group who visited the outpatient department of Pediatrics, Chungnam National University Hospital from January, 1984 to July, 1987 The results were as follows: 1) In 60 cases of control group between 1 to 15 year, hemoglobin was 12.5±1.7 gm/dl, MCV 82.4± 3.8 fl, and RDW 13.1 ±1.1% and...
A Case of Iron Deficiency Anemia with Hypoproteinemia.
Seong Ho Kim, Woo Kill Lee
Clin Exp Pediatr. 1988;31(8):1054-1058.   Published online August 31, 1988
Severe iron deficiency anemia is occasionally accompanied by hypoproteinemia and edema. There is evidence that the hypoproteinemia is caused by increased intestinal loss of serum protein. We experienced a case, 1 year and 6 months old female patient with generalized edema, diagnosed as iron deficiency anemia with hypoproteinemia. After treatment with ferrous iron preparation, generalized edema was subsided, and hemoglobin value and serum protein...
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