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Case Report
A Case of Fixed Drug Eruption Due to Acetaminophen
Eui Jeong Min, Dae Hyun Lim, Jung Hee Kim, Seung Won Choi, Byong Kwan Son
Clin Exp Pediatr. 2000;43(8):1149-1152.   Published online August 15, 2000
Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often leaves residual hyperpigmentation. Commonly implicated substances are phenolphthalein, barbiturates, sulfonamides, tetracyclines, salicylates, gold and pyrazolone derivatives. Despite frequent use of acetaminophen, drug eruptions, especially fixed drug eruptions, due...
Original Article
The Relation of Food-Specific IgE to Recurrent Wheezing Attack
Yun Jeong Yang, Jeong Hee Kim, Yoo Mee Choi, Dae Hyun Lim, Sei Woo Chung, Jeong Gyu Kim, Byong Kwan Son
Clin Exp Pediatr. 1999;42(8):1056-1062.   Published online August 15, 1999
Purpose : There were some reports that IgE-mediated food hypersensitivity is associated with subsequent development of atopic disease in wheezy infants. So we carried out this study to show whether the food specific IgE antibodies are useful to predict recurrent wheezing attack in wheezy infants. Methods : A total of 190 children younger than 4-year-old were enrolled in this study. They...
A Nationwide Clinical Study of Acute Respiratory Distress Syndrome in Children
Soo Jung Choi, Do Suck Jeong, Jae Won Oh, Ha Baik Lee, Im Ju Kang, Kwang Woo Kim, Kyu Earn Kim, Ki Bok Kim, Young Ho Rah, Kang Seo Park, Byong Kwan Son, Ki Young Lee, Sang Il Lee, Ji Tai Choung, Young Mi Hong
Clin Exp Pediatr. 1999;42(1):23-31.   Published online January 15, 1999
Purpose : Acute respiratory distress syndrome(ARDS) is the final course of acute lung injury. It results from various etiological origins and pathophysiologic mechanisms, and has a mortality rate of approximately 60-70%. Although the confirmative incidence of ARDS in children is yet unknown, the increasing incidence of ARDS has been reported in Korea. In the present study, we report ARDS diagnosed...
Case Report
A Case of Idiopathic Pulmonary Hemosiderosis Improved with Steroid Inhalation
Young Se Kwon, Jeong Hee Kim, Dae Hyun Lim, Soon Ki Kim, Sei Woo Chung, Byong Kwan Son
Clin Exp Pediatr. 1998;41(8):1153-1156.   Published online August 15, 1998
Original Article
Use of Erythema as An Interpreting Index of the Skin Prick Test
Ji Eun Lee, Jeong Hee Kim, Dae Hyun Lim, Sei Woo Chung, Byong Kwan Son
Clin Exp Pediatr. 1998;41(7):966-973.   Published online July 15, 1998
Purpose : There are many methods to interpret the skin prick test which has been commonly used to find out the causative allergen in allergic disease. Among them two are most frequently used. One is to measure the absolute size of wheal which is caused by the allergen and the other is to compare the size of wheal for allergen...
The Diagnostic Significance of MCV, MCH, and RDW in Anemia of Kawasaki Disease
Ji Eun Lee, Yoon Hyung Park, Seung Baik Han, Soon Ki Kim, Sei Woo Chung, Jeung Gyu Kim, Byong Kwan Son
Clin Exp Pediatr. 1998;41(2):230-236.   Published online February 15, 1998
Purpose : We investigated what kind of factors are the most stable among hemoglobin(Hb), hematocrit(Hct), MCV, MCH and RDW as a marker of discriminating anemia due to an acute inflammation from anemia of different origins. Methods : We evaluated 141 patients with Kawasaki disease who had been admitted to the Department of Pediatrics, Inha hospital from 1990 to 1995. We...
Influences of the Intrapulmonary R→L Shunt on PaO2 and PaCO2 after Instillation of Exogenous Pulmonary Surfactant to Premature Neonates with Respiratory Distress Syndrome
Yoon Hyung Park, Sei Woo Chung, Seung Baik Han, Young Se Kwon, Ji Youn Kim, Woo Sik Cheong, Dae Hyun Lim, Byong Kwan Son
Clin Exp Pediatr. 1997;40(11):1508-1519.   Published online November 15, 1997
Purpose : We are inclined to analyze the relationship between the intrapulmonary right-to-left shunt and the PaO2/PaCO2 after endotracheal single-dose surfactant instillation to premature neonates with respiratory distress syndrome within 6 hours after birth. Methods : From Jan. 1993 to Jun. 1995, we have conducted a clinical trial of surfactant replacement therapy to the premature neonates with respiratory distress syndrome at the neonatal intensive care unit...
Complications, Apolipoproteins and Lipoprotein(a) in Severely Obese Children in Incheon, 1996
Yon Ho Choe, Yong Hoon Jun, Soon Ki Kim, Seung Kyu Han, Byong Kwan Son, Jong Weon Choi, Soo Hwan Pai
Clin Exp Pediatr. 1997;40(10):1386-1393.   Published online October 15, 1997
Purpose : This study was designed to evaluate the incidence of complication in severely obese children and to determine whether the difference of Lp(a) between severely obese children and normal control group exists. Methods : Body weight, height and obesity index were measured in 5885(M:F= 3089:2796) elementary school children. Eight eight(M:F=63:25) were selected as severely obese children. Of the 88 children, 74 agreed to venous...
Clinical Review of Recurrent Kawasaki Disease
Jong Woon Choi, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1996;39(8):1139-1145.   Published online August 15, 1996
Purpose : The recurrence of Kawasaki disease has not been considered significant and has not been reported on literatures in Korea. Authors reviewed cases with recurrent Kawasaki disease to get informations about recurrent Kawasaki disease and to know whether there is any factor, if present, that can predict recurrence. Methods : We reviewed and analyzed the hospital records of patients with recurrent Kawasaki disease who...
Normal Predicted Value of Airway Resistance by Flow Interrupter Technique in Korean Primary School-Aged Children
Byong Kwan Son, Dae Hyun Lim, Jeong Hee Kim, Jong Woon Choi, Soon Ki Kim, Sei Woo Chung
Clin Exp Pediatr. 1996;39(8):1095-1102.   Published online August 15, 1996
Purpose : To get the normal predicted value of airway resistance in Korean primary school-aged children by using flow interrupter technique which is simple and easy enough to be applicable even to young children. Methods : Among all the children of one primary school, we selected 964 (Male 469, Female 495). Excluded children were out of normal range in growth with Korean standard and/or...
The Optimal Dosages of Gammaglobulin and Aspirin in Treating Kawasaki Disease
Seung Baik Han, Jong Woon Choi, Soon Ki Kim, Sei Woo Chung, Jeung Gyu Kim, Byong Kwan Son
Clin Exp Pediatr. 1996;39(5):703-711.   Published online May 15, 1996
Purpose : There are some disagreements about the optimal dosages of intravenous gammaglobulin(IVGG) and oral aspirin(ASA) in the treatment of Kawasaki disease. So authors performed a prospective clinical study to evaluate the efficacy of IVGG 1g/kg plus ASA 50mg/kg/day. Methods : We treated 29 patients who were admitted to Inha University Hospital from June 1993 through May 1994 with IVGG 1g/kg plus ASA 50mg/kg/d. We...
Studieson NormalValuesforRed Blood Cells in Korean Children
Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1996;39(5):673-681.   Published online May 15, 1996
Purpose : Values for hemoglobin, erythrocyte indices and red cell distribution width used in the diagnosis of anemia and iron deficiency are known to vary to some degree according to age. We tried to define age-related changes in red blood cells (RBC) profiles. Methods : With the eletronic counters routinely used in clinical laboratories we evaluated the RBC profiles of 1,717 samples of blood from...
Epidemiologic Study of Measles Outbreak in School-Aged Children in East KyongGi-Do Area
In Kyu Yi, Jong Woon Choi, Soon Ki Kim, Byong Kwan Son, Jeung Gyu Kim, Seong Ki Yu, Myung Cheol Joe, Il Suk Jang
Clin Exp Pediatr. 1996;39(1):63-71.   Published online January 15, 1996
Purpose : There was marked decline of measles outbreak in the world since the first measles vaccine had been introduced. Recently, however, measles outbreak in the vaccinated children have been reported worldwide, which was ascribed to the possibilities of primary or secondary vaccine failure. We investigated the incidence in the school-aged children in the Kyong-gi Do area, the larger district...
Medical Lecture Course
Antibody Directed Cell Therapy in Pediatric AIDS
Byong Kwan Son
Clin Exp Pediatr. 1995;38(7):881-885.   Published online July 15, 1995
Original Article
Epidemiology and Vaccine Efficacy of Measles During the 1993 measles Epidemic
Soon Ki Kim, Jong Woon Choi, Byong Kwan Son, Seung Nam Park, Churl Young Chung, Young Min Ahn, Chong Young Park, Ki Yang Ryoo, Woo Kap Chung, Hoan Jong Lee
Clin Exp Pediatr. 1995;38(6):778-785.   Published online June 15, 1995
Purpose : Because of increased measles incidence in Korea during 1993 and the recent finding of genomic differences between vaccine virus and contemporary wild measles viruses, we conducted a measles vaccine efficacy study involving children ages 1 to 5 yeark, with the demographic analysis of patients brought to the hospitals during measles outbreak that had occurred 1993 in Seoul and...
Epidemiologic Study during 1993 Measles Outbreaks in Seongnam Area
Soon Ki Kim, In Kyoo Yi, Seung Kyoo Han, Jun Hee Park, Yun Jeong Chang, Jong Woon Choi, Jeung Gyu Kim, Byong Kwan Son
Clin Exp Pediatr. 1995;38(2):180-188.   Published online February 15, 1995
Purpose : Although remarkable progress has been made in efforts to control measles since measles vaccines became available for use, the long-term success of their vaccination programmes has been questioned, with the worldwide resurgence of the disease. This resurgence has increased attention on the inadequacy of current immunization programmes. In 1993 there have been measles outbreaks in Seong-nam city located...
Case Report
A Case of Burkitt's Lymphoma with Bilateral Renal Enlargement
Jun Hee Park, In Kyu Lee, Jong Woon Choi, Soon Ki Kim, Byong Kwan Son, Jin Ju Kim
Clin Exp Pediatr. 1995;38(1):122-128.   Published online January 15, 1995
Burkitt's lymphoma is a distinct pathologic entity characterized as a diffuse undifferentiated malignant lymphoma of B-lymphocyte origin. We experienced a case of Burkitt's lymphoma with bilateral renal enlargement in which a 3 year-old male patient was admitted with complaints of abdominal distention and facial edema. Laboratory examination revealed positivity for CD 19, CD 10, CD 20 and c-myc on flow cytometry, bilateral...
A Case of Pulmonary Blastoma
Yun Jeong Chang, Jeong Hee Kim, Sun Ki Kim, Byong Kwan Son, Joon Mi Kim, Young Chae Chu
Clin Exp Pediatr. 1994;37(7):999-1005.   Published online July 15, 1994
Pulmonary blastoma is a rare type of malignant lung tumor comprised of epithelial and mesenchymal elements reminiscent of fetal lung. Mesenchymal element may show various patterns of differentiation toward mature tissue, such as cartilage, smooth muscle, and bone. Rhabdomyoblastic differentiation in pulmonary blastoma is quite rare. Our case of pulmonary blastoma with rhabdomyoblastic differentiation documented by electron microscopy and immunohistochemistry. Usually...
Original Article
The Effect of Alfacalcidol in the Treatment of Idiopathic Myelofibrosis in Children
Soon Ki Kim, Jeong Hee Kim, Dae Hyun Lim, Jong Woon Choi, Byong Kwan Son, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(3):339-346.   Published online March 15, 1994
Idiopathic myelofibrosis (IMF), which is characterized by marrow fibrosis, leukoerythroblastic anemia, teardrop poikilocytosis and splenomegaly due to extramedullary hematopoiesis, has known to have no form of therapy. On the ground of the possibility of reversing collagen deposition in IMF using 1, 25-dihydroxycholecalciferol [1, 25(OH)2D3], we report here our observations of 5 patients (M:F = 1:4) with IMF before and after treatment...
Normal Predicted values of Pulmonary function Test in Korean Primary School-Aged Children
Dae Hyun Lim, Jeong Hee Kim, Jun Hee Park, Jong Woon Choi, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1994;37(2):240-249.   Published online February 15, 1994
Pulmonary function test is one of the most important tools in the management of patients with respiratory tract diseases and allergic diseases. As with the difficulties in performing the test, it has been seldom used in pediatric field. But with the advent of simple, computerized tools, pediatric pulmonologist and allergist try to manage the patients using PFE. Still the normal...
The Incidence of Allergic Disease among the Pediatric Outpatient
Jeong Hee Kim, Jun Hee Park, Dae Hyun Lim, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1994;37(1):9-18.   Published online January 15, 1994
The incidence of allergic disease in pediatric outpatient department of a hospital, where primary care is undertaking, was studied from Arp. 1, 1989 to Mar. 32, 1990. The results were as follows, 1) The incidence of respiratory tract disease was the highest with the value of 57.2% of the total patients, followsed by gastrointestinal tract disease (13.9%), infectious disease (6.7%), visit...
A Case of Estrogen-producing Sertoli-Leydig Cell Tumor with Precocious puberty.
Myung Sun Oh, Nan Kyoung Kim, Dae Hyun LIm, Jeung Hee Kim, Byong Kwan Son, In Suk Joo, Ku Sang Kim, Young Chai Joo
Clin Exp Pediatr. 1990;33(9):1301-1305.   Published online September 30, 1990
We have experienced a case of estrogen producing Sertoli-Leydig cell tumor with precocious puberty in a 2-year-old girl. Her chief complaints were breast enlargement, which was noticed 20 days prior to admission and vaginal bleeding, which was noticed 10 days prior to admission. The diagnosis was made on the basis of history, physical examination, ultra sonography, hormonal study, and histologic study after operation. She was...
A Case of Subdural Empyema Complicating Hemophilus Influenzae Meningitis.
Myung Sun Oh, Nan Kyung Kim, Sae Yoo Jung, Soon Ung Kang, Jung Kyou Kim, Byong Kwan Son
Clin Exp Pediatr. 1990;33(8):1129-1133.   Published online August 31, 1990
We have experienced Hemophilus influenzae meningitis complicated by subdural empyema, which was confirmed by computerized tomography and subdural tapping. The patient was 5-month-old female who was admitted with high fever and generalized siezure. Hemophilus influenzae meningitis was confirmed by the culture of spinal fluid. The organism was sensitive to the ampicillin but the clinical course was not satisfactory with persisting high fever because of complication....
Clinical Studies on Congenitally Corrected Transposition of the Great Arteries.
Byong Kwan Son, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong
Clin Exp Pediatr. 1986;29(3):287-295.   Published online March 31, 1986
The clinical studies were performed on 29 congenitally corrected transposition of£the great arteries (C-TGA) confirmed by cardiac catheterization and angiocardiography at the Department of Pediatrics, Seoul National University Hospital, from Oct. 1957 to Dec. 1984. The results are as follows; 1) There were 29 cases of C-TGA, representing 0.7% of a total of 4,096 CHD patients. The male： female ratio was 3.1 :...
Clinical observation on subacute bacterial endocarditis with emphasis on pulmonary perfusion scan in the diagnosis of pulmonary infarction.
Byong Kwan Son, Hyung Ro Moon
Clin Exp Pediatr. 1978;21(12):1110-1115.   Published online December 31, 1978
Total thirteen cases of subacute bacterial endocarditis were seen at the Department of Pediatrics, Seoul National University hospital from January 1971 to September 1978. Among them, twelve patients' medical records were analyzed for clinical data and particular attention was given on the usefulness of pulmonary perfusion scan in the diagnosis of pulmonary infarction, which is the one of the frequent...
Comparison of Tuberculine Testing Between Monotest and Mantoux.
Byong Kwan Son
Clin Exp Pediatr. 1977;20(12):959-964.   Published online December 31, 1977
The Monotest was compared with the Mantoux test. A total of 527 first grade primary school children were subjected to test. Each child was innoculated simultaneously to one side arm with protein purified derivatve(PPD, 1TU) and to the another side arm with Monovac(Institute Merieux). Results from each test were read seperately 72 hours after administration. When induration of 2mm or...
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