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Review Article
Allergy
Management of patients with allergic diseases in the era of COVID-19
Eun Lee
Clin Exp Pediatr. 2022;65(11):529-535.   Published online September 23, 2022
In the early days of the coronavirus disease 2019 (COVID-19) pandemic, allergic diseases, especially asthma, were considered to be risk factors for severe COVID-19 infection, hospitalization, and death. These concerns stemmed from the idea that individuals with allergic diseases are generally more susceptible to respiratory virus infections, which are major causes of exacerbation of allergic diseases. However, epidemiologic data with...
Phenotypes of allergic diseases in children and their application in clinical situations
Eun Lee, Soo-Jong Hong
Clin Exp Pediatr. 2019;62(9):325-333.   Published online April 23, 2019
Allergic diseases, including allergic rhinitis, asthma, and atopic dermatitis, are common heterogeneous diseases that encompass diverse phenotypes and different pathogeneses. Phenotype studies of allergic diseases can facilitate the identification of risk factors and their underlying pathophysiology, resulting in the application of more effective treatment, selection of better treatment responses, and prediction of prognosis for each phenotype. In the early phase...
Original Article
Allergy
Clostridium difficile colonization and/or infection during infancy and the risk of childhood allergic diseases
Sun Hwa Lee, Yun Na Gong, Eell Ryoo
Clin Exp Pediatr. 2017;60(5):145-150.   Published online May 31, 2017
Purpose

The gut microbiota can influence several diseases through immune modulation; however, the exact role of microbes such as Clostridium difficileand the relationship between microbiota colonization and allergic diseases are not well known. This study aimed to determine the relationship between C. difficilecolonization and/or infection (CDCI) during infancy and allergic diseases during early childhood.

Methods

Infants 1–12 months of age presenting changes in...

Review Article
Clinical significance of serum IgE
Hai Lee Chung
Clin Exp Pediatr. 2007;50(5):416-421.   Published online May 15, 2007
Many previous studies have proved that human allergic disease resulted from the formation of antibodies belonging to a unique immunoglobulin isotype termed immunoglobulin E (IgE). Most of IgE- producing plasma cells are found in the lymphoid tissue associated with the gastrointestinal and respiratory tracts. IgE may be found free in the mucosal secretions of these tissues, bound to local mast...
Medical Lecture Course
CpG DNA for Treatment of Allergic Diseases
Sung Min Choi
Clin Exp Pediatr. 2005;48(3):251-259.   Published online March 15, 2005
Atopy is a highly prevalent and serious health problem. The prevalence and severity of asthma and allergic diseases have increased over recent decades, particularly in industrialized nations. Early life infections may protect against the development of atopy and allergic diseases like asthma. The inverse relationship between the incidence of atopy and childhood infections has led to the 'hygiene hypothesis', which...
Original Article
The Significance of Family History, Immunoglobulin E, Total Eosinophils and Eosinophil Cationic Protein as a Predictor of Allergic Diseases
Dong Su Park, Hyun Hee Kim, Joon Sung Lee
Clin Exp Pediatr. 1998;41(9):1273-1282.   Published online September 15, 1998
Purpose : Family history of allergy and cord blood immunoglobulin E concentration have been proven to be predictors of the development of allergic diseases in children. The purpose of this study is to evaluate whether maternal, cord and baby's blood total eosinophils or eosinophil cationic protein(ECP) in addition to the above two predictors could be a predictor of subsequent allergic...
Availability of IgE MAST for Diagnosis of Asthmatic Children
Gwi Sook Kim, Hyung Jo Jung, Soo Kyung Lee, In Kyung Kim, Ho Sung, Chang Hee Choi
Clin Exp Pediatr. 1996;39(8):1130-1138.   Published online August 15, 1996
Purpose : The Skin prick test is simple and cheap in diagnosis of allergic diseases. So the skin prick test has been widely used as the initial diagnostic method of IgE-mediated allergic diseases with the merit of fast detection of causative allergens. But the skin test has some difficulties in application for the infants and young children. IgE MAST(multiple antigen simultaneous test) and IgE...
The Incidence of Allergic Disease among the Pediatric Outpatient
Jeong Hee Kim, Jun Hee Park, Dae Hyun Lim, Soon Ki Kim, Byong Kwan Son
Clin Exp Pediatr. 1994;37(1):9-18.   Published online January 15, 1994
The incidence of allergic disease in pediatric outpatient department of a hospital, where primary care is undertaking, was studied from Arp. 1, 1989 to Mar. 32, 1990. The results were as follows, 1) The incidence of respiratory tract disease was the highest with the value of 57.2% of the total patients, followsed by gastrointestinal tract disease (13.9%), infectious disease (6.7%), visit...
A clinical study on maxillary sinusitis in children with respiratory allergic disease.
Mi Young Yeo, Yong Tae Jung, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1991;34(12):1689-1698.   Published online December 31, 1991
A clinical and allergological evaluation was performed on 253 respiratory allegic children aged 3 to 15 who were taken Water’s view X-ray at Pediatric allergic clinic and in the ward from July 1986 to June 1990. The results were as follows; 1) Maxillary sinusitis was detected in 186 cases (73.5%) by Watr’s view X-ray in allergic asthma and rhinitis children. 2) There was no significant differences between blood...
A Survey of the Distribution of Allergic Diseases in Low Grade Children on Primary School.
Seung Hwan Kim, Seung Joo Kim, Hyun Soo Park, Chung Hun Lee, Hae Sun Yoon
Clin Exp Pediatr. 1988;31(10):1290-1300.   Published online October 31, 1988
The purpose of this study is to assess the incidence of allergic diseases in lower grade primary school children in Seoul, Chun cheon and Kuri by questionnaires which were completed by their parents. This study was done on 15,009 of possible 20,000 pupils from May to September, 1987. Thirty eight questions were used to elicit information about the relationship between allergic diseases and factors such...
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