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Original Article
Applying the bacterial meningitis score in children with cerebrospinal fluid pleocytosis: a single center's experience
Jungpyo Lee, Hyeeun Kwon, Joon Soo Lee, Heung Dong Kim, Hoon-Chul Kang
Clin Exp Pediatr. 2015;58(7):251-255.   Published online July 22, 2015

The widespread introduction of bacterial conjugate vaccines has decreased the risk of cerebrospinal fluid (CSF) pleocytosis due to bacterial meningitis (BM) in children. However, most patients with CSF pleocytosis are hospitalized and treated with parenteral antibiotics for several days. The bacterial meningitis score (BMS) is a validated multivariate model derived from a pediatric population in the postconjugate vaccine era and...

Bacterial meningitis in children experienced at a university hospital, 1993-2006
Sung Yoon Cho, Tae Yeon Kim, Hyunju Lee, Kyung Hyo Kim, Eun Sun Yoo, Hae Soon Kim, Eun Ae Park, Kyung Ha Ryu, Jeong Wan Seo, Sejung Sohn, Seung Joo Lee
Clin Exp Pediatr. 2008;51(10):1077-1084.   Published online October 15, 2008
Purpose : Despite the seriousness of bacterial meningitis in children, there is little information on the incidence, causative organisms, mortality rate and age distribution. We studied the frequency by age group and causal pathogens, and clinical characteristics in children with bacterial meningitis in the private sector in Korea. Methods : The medical records containing the data on bacterial meningitis patients...
Causative Organisms in Children with Bacterial Meningitis(1992-2002)
Hyun-Jung Kim, JI-Won Lee, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Seung-Hoon Hahn, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(11):1085-1088.   Published online November 15, 2003
Purpose : This study was performed to assess the difference of organisms causing bacterial meningitis according to time. Methods : We analyzed retrospectively 40 medical records of bacteriologically proven meningitis from 1992 to 2002. We divided them into two groups; neonate's group(14 cases), and children's group(26 cases). The results of the neonate's group were compared with those of previously reported articles...
Lumbar Puncture in Patients Who Experienced First Seizure with Fever
Jung Kim, Jun Su Lee, Sang Eun Lee, Wan Suk Choi, Sung Ryoung Han, Kyunglae Cho
Clin Exp Pediatr. 2003;46(10):1008-1012.   Published online October 15, 2003
Purpose : We aimed to ascertain whether lumbar punctures should be done to prove febrile seizure, and to study what conditions can delay or abolish lumbar puncture. Methods : This retrospective study was done for four years, from January, 1996 to December, 1999. The subjects were the patients who visited Masan Samsung Hospital for the first convulsion with fever, and...
Prognostic Value of Repeated Cerebrospinal Latex Agglutination Testing in Bacterial Meningitis
Soo Jeong Lee, So Hyun Ahn, Su Jin Cho, Hae Soon Kim, Seung Joo Lee
Clin Exp Pediatr. 2003;46(4):345-350.   Published online April 15, 2003
Purpose : Bacterial meningitis is a serious infection of childhood associated with a significant morbidity and mortality. Repeated cerebrospinal fluid(CSF) examination is a useful prognostic indicator and a delayed sterilization is associated with a higher incidence of neurologic abnormalities. In this study we tried to determine the prognostic value of repeated CSF latex agglutination testing. Methods : We retrospectively evaluated 19...
Change of Cerebrospinal Fluid Ferritin in Children with Meningitis
Mee Hee Youm, Eun Young Kim, Young Jong Woo, Hyun Ju Park, Chan Jong Kim
Clin Exp Pediatr. 2000;43(8):1068-1073.   Published online August 15, 2000
Purpose : Despite the advent of new and more potent antibiotics, mortality and morbidity rates due to bacterial meningitis remain stagnant. Rapid detection of microorganism and early antibiotics treatment are the most important prognostic factors of bacterial meningitis. For early diagnosis of bacterial meningitis biochemical markers such as lactic dehydrogenase, lactic acid, C-reactive proteia have been measured in cerebrospinal fluid....
Diagnostic Value of Urine Latex Test In Bacterial Meningitis
Seung Min Lee, Eun Ae Park, Seung Joo Lee
Clin Exp Pediatr. 2000;43(1):55-59.   Published online January 15, 2000
Purpose : Bacterial meningitis in childhood carries significant mortality and morbidity, so accurate and rapid diagnosis is important. Cerebrospinal fluid(CSF) latex agglutination test has been used for rapid diagnosis of bacterial meningitis. However, urine may be the best specimen for a latex test, because bacterial antigens are concentrated in the urine. The study tried to determine the diagnostic value of urine latex test in...
The Diagnostic Value of CSF Tumor Necrosis Factor-α for Early Diagnosis of Bacterial Meningitis
So Young Park, Soo Ja Hwang, Eun Ae Park, Jung Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1998;41(8):1078-1083.   Published online August 15, 1998
Purpose : During the course of bacterial meningitis, TNF-α produced by macrophages and monocytes in response to LPS and other inflammatory and immune stimulation, is now recognized as a primary mediator in the pathogenesis of infection, injury and inflammation and in the process of host defence. TNF-α was increased vascular permeability by inducing morphologic and structural changes of endothelial cells...
Prognosis of Bacterial Meningitis based on Cerebrospinal Fluid Culture
Yun Ju Lee, Won Sung Lee, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(5):614-621.   Published online May 15, 1998
Purpose : The present study was undertaken to assess whether the results of cerebrospinal fluid (CSF) culture are related to prognosis. Methods : Subjected to this study were 51 cases admitted to our department who had been diagnosed as bacterial meningitis. They were divided into two groups, Group Ⅰ(20) with positive CSF culture and Group Ⅱ(31) with negative outcome, then both...
The Therapeutic Effects of Dexamethasone Therapy in Neonate with Bacterial Meningitis
Eun Gyung Lee, Kook In Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Kwan Han
Clin Exp Pediatr. 1995;38(5):602-611.   Published online May 15, 1995
Purpose : In experimental models of meningitis and in children with meningitis, dexametha-sone has been shown to reduce meningeal inflammation and to improve the outcome of disea-se. We studied the effects of dexamethasone administration in neonates(<2 month-old) with b-acterial meningitis. Methods : We retrospectively reviewed the medical records of 30 neonates admitted to the nursery, the Yonsei University College of Medicine...
A clinical study on neonatal bacterial meningitis.
Yong Won Park, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(6):763-770.   Published online June 30, 1991
Clinical courses of 12 neonates who were confirmed as neonatal bacterial meningitis by CSF culture or CSF latex agglutination test from January, 1986 to June, 1990, emphasizing on their complications and treatments, were evaluated. The results were summarized as follows; 1) The most common etiologic organism was E. coli (33.3%). 2) Two most common complications were ventriculitis (66.7%) and hydrocephalus (66.7%). 3) EVD with intraventricular antibiotics therapy was only...
A Case of Recurrent Bacterial Meningitis with CSF Rhinorrhea.
Dae Shik Kim, Jin Yong Lee, Chang Jun Coe, Jin Suk Suh
Clin Exp Pediatr. 1989;32(8):1161-1166.   Published online August 31, 1989
Recurrent bacterial meningitis is a rare disease which is associated with congenital or acquired anatomical defects of CNS and surround structures, or it may be due to parameningeal foci of infection, defects in immune response, and post-operative state of shunt procedure in hydrocephalus. We experienced the patient of recurrent bacterial meningitis with CSF rhinorrhea due to structural defect which was not defined exactly. We identified...
A Case of Recurrent Bacterial Meningitis due to Congenital Cribriform Plate Defect.
Hong Chul Lee, Jong Leam Choi, Wan Soeb Kim, Myung Ho Lee
Clin Exp Pediatr. 1989;32(3):412-417.   Published online March 31, 1989
One patient with a history of recurrent bacterial meningitis was examined with skull and sinus radiographs, routine cranial computed tomography and immunologic evaluation. None of these studies were diagnostic. Thin-section (1-2 mm) direct coronal computed cranial tomography demonstrated congenital cribriform plate defect. This patient was repaired surgically and no further meningitis has developed for 16 months
Clinical Observations of Meningitis.
Byoung Hoon Lee, Hyung Keun Nam, Myung Ik Lee, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(2):180-190.   Published online February 28, 1989
The 267 cases of meningitis were observed at National Medical Center between Jan. 1st 1979 and May 31, 1986. The results were as follow; 1) In BM and TM sexual difference was not notice, but male was more in AM. 2) In BM infancy was the most common, but school age was common was AM. 3) Most cases developed during spring in BM and TM...
Cerebrospinal Fluid Lymphocytosis in Acute Bacterial Meningitis on Children.
Hong Kun Kim, Woo Gill Lee
Clin Exp Pediatr. 1988;31(6):707-714.   Published online June 30, 1988
Clinical and laboratory analysis of 78 cases of acute bacterial meningitis diagnosed by cere- brospinal (CSF) culture under 15 years old was made, retrospectively from Jan. 1973 to Dec. 1986, who were admitted to the Department of Pediatrics Hanyang University Hospital. The results analysed were as follows: 1) CSF lymphocytosis (more than 50% lymphocytes or mononuclear cells)occurred in 18 of 78 cases (23%) of bacterial meningitis. 2) There...
Case Report
A Case of Recurrent Bacterial Meningitis Secondary to the Defect of Stapes Footplate.
Soon Hee Eom, Joo Hong Cha, Byoung Soo Cho, Sa Jun Chung, Chang Il Ahn, Chang Il Cha
Clin Exp Pediatr. 1986;29(7):779-783.   Published online July 31, 1986
With the dramatic lowering the mortality rate of bacterial meningitis since the introduction of antibacterial agents, multiple attacks of bacterial meningitis no longer are a curiosity. So multiple attacks of bacterial meningitis may be the only indication of the existence of an abnormal communication between the nasopharynx or ear and the meningeal space and such a communication must be found. We...
A Case of Eosinophilic Granuloma with Recurrent Bacterial Meningitis associated with CSF Rhinorrhea.
Eung Deok Choi, Mee Kyung Namgoong, Seung Ha Yoo, Baek Keun Lim, Jong Soo Kim, Tae Seung Kim
Clin Exp Pediatr. 1986;29(2):209-214.   Published online February 28, 1986
We experienced a case of eosinophilic granuloma with multiple lesions on skull, ribs, vertebrae, tibia and pelvic bone. In addition, recurent bacterial meningitis was associated with CSF rhinorrhea probably due to osteolytic lesion of eosinophilic granuloma in the same patient. A brief review of literature was made.
Original Article
A Clinical Observation on Neonatal Bacterial Meningitis.
Young Ju Lee, Bu Kwun Jung, Soon Ok Byun, Myung Hi Shin, Ji Sub Oh
Clin Exp Pediatr. 1983;26(9):872-883.   Published online September 30, 1983
A clinical observation was made on 80 cases of neonatal bacterial meningitis who were admitted to the department of Pediatrics at Wallace Memorial Baptist Hospital, Busan, Korea, during a 8 years period between Jan, 1, 1975 and Dec. 31, 1982. 1) There was no significant differences in annual incidence. The incidence of neonatal bacterial meningitis was 0.34% of total admissions in Ped. dept, and...
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