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Original Article
Usefulness of serum cystatin C to determine the dose of vancomycin in neonate
Jeong Eun Shin, Soon Min Lee, Ho Seon Eun, Min Soo Park, Kook In Park, Ran Namgung
Clin Exp Pediatr. 2015;58(11):421-426.   Published online November 22, 2015
Purpose

The vancomycin dosage regimen is regularly modified according to the patient's glomerular filtration rate (GFR). In the present study, we aimed to assess the usefulness of serum cystatin C (Cys-C) concentration, compared with serum creatinine (SCr) concentration, for predicting vancomycin clearance (CLvcm) in neonates.

Methods

We retrospectively analyzed the laboratory data of 50 term neonates who were admitted to the neonatal intensive...

The impact of early detection through school urinary screening tests of membranoproliferative glomerulonephritis typeⅠ
Sung-Hoon Chung, Sung-Sin Park, Sung-Do Kim, Byoung-Soo Cho
Clin Exp Pediatr. 2007;50(11):1104-1109.   Published online November 15, 2007
Purpose : Since 1998, school urinary screening tests have been performed on Korean school children. We could detect and treat so many asymptomatic chronic renal disease in early stage. We investigated the efficacy of school urinary screening tests from children with membranoproliferative glomerulonephritis (MPGN) type I. Methods : We analyzed the characteristics and prognosis of 18 patients with MPGN type I...
Case Report
Two Cases of Gitelman's Syndrome Diagnosed by Renal Clearance Study
Tae Hwa Kim, Seung Jun Kim, Yu Kyung Seo, Jung-Yeon Shim, Hye Lim Jung, Moon Soo Park, Dong Hyuk Kum
Clin Exp Pediatr. 2002;45(3):413-417.   Published online March 15, 2002
Gitelman's syndrome is an autosomal recessive disorder characterized by hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalciuria that has recently been reported to be linked to thiazide-sensitive Na-Cl cotransporter gene mutation. In this study, we performed renal clearance studies to differentiate Gitelman's from Bartter's syndrome and to confirm the diagnosis in two patients clinically diagnosed with Gitelman's syndrome. Each patient was hydrated...
Original Article
Renal Problems in Wilson Disease
Il Soo Ha, Jun Ho Lee, Yeon Ho Choe, Hae Il Cheong, Sei Won Yang, Young Yull Koh, Jeong Kee Seo, Yong Choi
Clin Exp Pediatr. 1999;42(6):817-824.   Published online June 15, 1999
Purpose : Wilson disease is a hereditary metabolic disorder characterized by an accumulation of copper in tissues which sometimes results in renal problems. This study was performed to evaluate the prevalences of the renal problems in Wilson disease and related risk factors. Methods : In 31 patients with Wilson disease, we looked for renal problems by history taking, physical examination...
The Study of Creatinine Clearance in Neonates.
Dong Sun Hong, Moon Ja Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(2):139-143.   Published online February 28, 1987
The creatinine clearance rate, an index of glomerular filtration rate, has been reported to develop according to gestational and postnatal age. The purpose of this study is to examine changes in creatinine clearance with gestational age and postnatal age in preterm and full term healthy neonates. The results were as follows: 1) The creatinine clearance rate increased according to gestational age. 2) The most in creament of creatinine...
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