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Original Article
Usefulness of serum cystatin C to determine the dose of vancomycin in neonate
Jeong Eun Shin, Soon Min Lee, Ho Seon Eun, Min Soo Park, Kook In Park, Ran Namgung
Clin Exp Pediatr. 2015;58(11):421-426.   Published online November 22, 2015

The vancomycin dosage regimen is regularly modified according to the patient's glomerular filtration rate (GFR). In the present study, we aimed to assess the usefulness of serum cystatin C (Cys-C) concentration, compared with serum creatinine (SCr) concentration, for predicting vancomycin clearance (CLvcm) in neonates.


We retrospectively analyzed the laboratory data of 50 term neonates who were admitted to the neonatal intensive...

Comparison of various methods of glomerular filtration rate measurements in children
Na Mi Lee, In Seok Lim
Clin Exp Pediatr. 2009;52(9):999-1004.   Published online September 15, 2009

Purpose:Glomerular filtration rate (GFR) is a fundamental parameter in assessing renal function and predicting the progression of chronic renal disease. Because the use of serum creatinine has several disadvantages, many studies have investigated the use of cystatin C for estimating GFR. We compared creatinine clearance and GFR with formulas using serum creatinine and cystatin C. Methods:We retrospectively analyzed 211 patients...
The Value of Serum Concentration of Cystatin C as a Marker for Glomerular Filtration Rate in Children and Adolescents
Young-Su Jung, In-Seok Lim
Clin Exp Pediatr. 2005;48(6):614-618.   Published online June 15, 2005
Purpose : Cystatin C has been proposed for the assessment of glomerular filtration rate, being more accurate than creatinine determination. We measured serum cystatin C concentrations in the pediatric population, and analysed the correlation between cystatin C and glomerular filtration rate. Methods : Cystatin C and creatinine were measured by the particle enhanced nephelometric immunoassay and Jaff method, respectively, in...
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