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Review Article
Early-onset epileptic encephalopathies and the diagnostic approach to underlying causes
Su-Kyeong Hwang, Soonhak Kwon
Clin Exp Pediatr. 2015;58(11):407-414.   Published online November 22, 2015

Early-onset epileptic encephalopathies are one of the most severe early onset epilepsies that can lead to progressive psychomotor impairment. These syndromes result from identifiable primary causes, such as structural, neurodegenerative, metabolic, or genetic defects, and an increasing number of novel genetic causes continue to be uncovered. A typical diagnostic approach includes documentation of anamnesis, determination of seizure semiology, electroencephalography, and...

Case Report
A Case of Early Infantile Epileptic Encephalopathy
Sang Mi Ha, Hee Jung Jung
Clin Exp Pediatr. 1992;35(11):1590-1596.   Published online November 15, 1992
Early infantile epileptic encephalopathy is characterized by its early onset (less than 3 months of age), frequent tonic spasms, suppression-burst on EEG, extremely poor response to treatment and grave outcome. The authors experienced a case of early infantile epileptic encephalopathy. The patient was a 1-month-old girl with a complaint of generalized tonic convulsion since 2 days of age, and her EEG...
Original Article
A Case of Early Infantile Epileptic Encephalopathy with Suppression-burst.
Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1989;32(9):1320-1323.   Published online September 30, 1989
The authors experienced a case of 45-day-old female newborn infant who showed the intractable tonic spasms with series formation and hypotonia. We diagnosed it through the evaluation of the clinical, radiological features including brain CT and electroencephalogram. The suppresion-burst pattern in EEG and clinical features aid to the confirmation of the diagnosis. A brief review of the related literature were made.


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