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Original Article

The Effect of Erythromycin on Gastric Antrum and Low Esophageal Sphincter in the Newborn Rabbit

Sung Dong Choi, Chung Sik Chun

Clin Exp Pediatr. 2000;43(1):34-42. Published online January 15, 2000

Purpose : We studied smooth muscle strips from rabbit gastric antrum and low esophageal sphincter(LES) to explore the difference between newborn and adult rabbit on erythromycin(EM)- induced contractions. Another aim of this study was to determine the mechanism of LES contractile activities induced by erythromycin(EM). Methods : Muscle strips prepared from newborn and adult rabbits were stimulated with agonists such as KCl, motilin and EM,...

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