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Original Article
Long-term neurological cognitive, behavioral, functional, and quality of life outcomes after fetal myelomeningocele closure: a systematic review
Andre Marolop Pangihutan Siahaan, Martin Susanto, Sarma Nursani Lumbanraja, Dwi Herawati Ritonga
Clin Exp Pediatr. 2023;66(1):38-45.   Published online November 30, 2022
· Fetal myelomeningocele closure significantly improved long-term neurological cognitive, behavioral, functional, and quality of life outcomes, most likely by reducing hydrocephalus rates.
· However, fetal myelomeningocele closure is associated with a significant risk of pregnancy complications, especially premature rupture of membranes and preterm delivery.
Review Article
Neonatology (Perinatology)
Fetal and preterm infant microbiomes: a new perspective of necrotizing enterocolitis
Yong-Sung Choi, In Gyu Song
Clin Exp Pediatr. 2017;60(10):307-311.   Published online October 20, 2017

Necrotizing enterocolitis (NEC) is a devastating condition of hospitalized preterm infants. Numerous studies have attempted to identify the cause of NEC by examining the immunological features associated with pathogenic microorganisms. No single organism has proven responsible for the disease; however, immunological studies are now focused on the microbiome. Recent research has investigated the numerous bacterial species residing in the body...

Evidence for adverse effect of perinatal glucocorticoid use on the developing brain
Young Pyo Chang
Clin Exp Pediatr. 2014;57(3):101-109.   Published online March 31, 2014

The use of glucocorticoids (GCs) in the perinatal period is suspected of being associated with adverse effects on long-term neurodevelopmental outcomes for preterm infants. Repeated administration of antenatal GCs to mothers at risk of preterm birth may adversely affect fetal growth and head circumference. Fetal exposure to excess GCs during critical periods of brain development may profoundly modify the limbic...

Case Report
Misdiagnosis of fetus-in-fetu as meconium peritonitis
Yoon Joo Kim, Se Hyung Sohn, Ju Young Lee, Jin A Sohn, Eun Hee Lee, Ee Kyung Kim, Chang Won Choi, Han Suk Kim, Beyong Il Kim, Jung Hwan Choi
Clin Exp Pediatr. 2011;54(3):133-136.   Published online March 31, 2011

Fetus-in-fetu (FIF) is a rare congenital condition in which a fetiform mass is detected in the host abdomen and also in other sites such as the intracranium, thorax, head, and neck. This condition has been rarely reported in the literature. Herein, we report the case of a fetus presenting with abdominal cystic mass and ascites and prenatally diagnosed as meconium...

A Case of Fetal Hepatic Calcificaion with a Good Prognosis
Kyong Hee Na, Hyun Jung Lee, Sung Soo Kim, Eun Young Kim, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2002;45(3):395-400.   Published online March 15, 2002
Recently, the increasing use of antenatal high resolutional ultrasonographic studies, and the increasing expertise of sonographers have contributed to the more frequent prenatal detecton of fetal hepatic calcification. Fetal hepatic calcification can arise from peritoneal, ischemic, infectious, neoplastic, and idiopathic causes. There are many reports that the prognosis is good in isolated fetal hepatic calcification without chromosomal aberrations, associated congenital...
Original Article
Diagnosis and Treatment of Fetal Cardiac Anomalies
Nam Su Kim, Myung Kul Yum, Hahng Lee, Sung Ro Jung, Jung Bae Yoo, Jae Ek Lee
Clin Exp Pediatr. 1996;39(10):1395-1404.   Published online October 15, 1996
Purpose : Fetal echocardiography is used for the prenatal diagnosis of congenital heart disease. Fetal echocardiography allows decisions to be made in advance where the fetal abnormality is not compatible with life after delivery or where early correction is required. Our fetal echocardiographic experience was analysed retrospectively to guide future clinical application. Methods : 138 mothers had fetal echocardiography from April 1992 to December...
Case Report
A Case of Fetus-in-Fetu
Jong Hyun Kim, Ik Jun Lee
Clin Exp Pediatr. 1993;36(12):1761-1764.   Published online December 15, 1993
Fetus-in-fetu is a very rare condition in which a malformed monozygotic twin lies within the body of its fellow, usually in the retroperitoneal cavity. Today it is generally accepted that the distinction between fetus-in-fetu and teratoma is largely determined by whether an axial skeleton system is present. We experienced a 6 months female infant who admitted to our unit because of...
Original Article
Outcome in Infants of Mothers with Systemic Lupus Erythematosus
Chang Ryul Kim, Young Pyo Chang, Hee Seop Kim, Mi Jung Kim, Byung Il Kim, Jung-Hwan Choi, Chong Ku Yun, Bo Hyun Yoon, Hee Chul Syn, Syng Wook Kim, Seon Yang Park, Hahng Lee
Clin Exp Pediatr. 1993;36(6):791-804.   Published online June 15, 1993
A large proportion of patients with systemic lupus erythematosus(SLE) are women of reproductive age. Their fetal outcome is undoubtedly less favourable than in haelthy women. Although there is no evidence of an increase in congenital anomalies, increased frequencies of miscarriage, stillbirth, growth retardation, and preterm delivery are recognized It mainly depends on the compromise of uteroplacental circulation such as renal...
Quantitative Assessment of the Diameters of Tricuspid Valve, Mitral Valve and Great Arteries in the Normal Human Fetus -Cross Sectional Echocardiographic Study-
Jung Yun Choi, Kyung Hee Park, Chung Il Noh, Yong Soo Yun, I Seok Kang, Eun Sook Han
Clin Exp Pediatr. 1992;35(11):1566-1572.   Published online November 15, 1992
In order to assess the growth of the mitral valve, tricuspid valve, and the aortic and pulmonary pathways in the normal human fetus, 181 fetal echocardiograms taken from 127 pregnant women (some women had repeated examinations) were analysed. Diameters were measured from cross sectional images and were correlated with gestational period. The diameter ratios of tricuspid valve/mitral valve, aorta/main pulmonary artery,...
Weight and morphologic development of prenatal human thymus.
Il Soo Ha, Kwang Wook Ko, Je Geun Chi
Clin Exp Pediatr. 1991;34(8):1057-1069.   Published online August 31, 1991
Thymus is a primary lymphoid organ which has an important role in maturation of immune competence. This organ matures earlier than the other organs, and the informations about its prenatal development are essential to understand the maturation of human immunity. To delineate the weight and morphologic development of prenatal thymus, the authors measured the weight of 221, and observed gross and histologic features of...
Morphological study on the development of human fetal kidney.
Hee Young Shin, Kwang Wook Ko, Je Geun Chi
Clin Exp Pediatr. 1991;34(8):1045-1056.   Published online August 31, 1991
A total of 293 human fetal kidneys, including those of 42 embryos are studied for the elucidation of temporal development of the kidney. These specimens were interpreted as normal by thorough postmortem examinations. The age of the specimens was determined by developmental horizon criteria in embryos and by correlating crown-rump length in fetuses. Embryos were embedded in toto, cut in various planes and reconstructed...
A Case of Surviving infant born with fetus papyraceus.
Kang Oh Lee, Soo Gi Kang, Hyung Ja Park, Shinna Kim
Clin Exp Pediatr. 1989;32(8):1128-1131.   Published online August 31, 1989
Fetus papyraceus is a rare complication in multiple pregnancy. Intrauterine death of one fetus of the twin usually occurs before second trimester and remained in place compressed between uterine wall and membrane of living twin until the end of the pregnancy. A case of surviving infant bom with fetus papyraceus is presented with brief review of literatures.
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