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Impact of Host Genetics on Susceptibility and Outcome of Viral Infections

Eun Hwa Choi

Clin Exp Pediatr. 2004;47(8):815-820. Published online August 15, 2004

The generation of a draft sequence of the human genome has lead to an opportunity to characterize human diversity, including the differences in host response to numerous pathogens. Host responses upon exposure to a pathogen can determine the wide spectrum of illness from subclinical or mild to severe diseases. Host factors, particularly genetic backgrounds, influence the pathogenesis of infectious diseases....

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