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Hutchinson-Gilford progeria syndrome is a rare genetic disease of unknown etiology with some features suggestive of accelerated aging. Patients with this disorder are usually of average intelligence and appear clinically normal at birth. However, in early childhood they develop severe growth retardation and a senescent phenotype, including balding, aged-appe-aring skin, generalized atherosclerosis, and strokes. They die prematurely as a result... |
