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Review Article
Infection
Global varicella vaccination programs
Young Hwa Lee, Young June Choe, Jia Lee, Eunseong Kim, Jae Young Lee, Kwan Hong, Yoonsun Yoon, Yun-Kyung Kim
Clin Exp Pediatr. 2022;65(12):555-562.   Published online November 2, 2022
It is important to evaluate its effectiveness at the national level and to determine the varicella vaccine schedule based on the evidence generated through the studies.
Original Article
General Pediatrics
Risk factors for childhood pneumonia: a case-control study in a high prevalence area in Indonesia
Vivi Ninda Sutriana, Mei Neni Sitaresmi, Abdul Wahab
Clin Exp Pediatr. 2021;64(11):588-595.   Published online March 15, 2021
Question: Is the incidence of childhood pneumonia influenced by breastfeeding and basic immunization status?
Finding: Exclusive breastfeeding and complete basic immunization status have an effect in limiting the incidence of childhood pneumonia.
Meaning: While exclusive breastfeeding and complete basic immunization the Expanded Program on Immunization status are important factors for reducing the incidence of childhood pneumonia, indoor air pollution was also a significant risk factor.
Review Article
Recommended immunization schedule for children and adolescents: Committee on Infectious Diseases of the Korean Pediatric Society, 2018
Eun Hwa Choi, Su Eun Park, Yae-Jean Kim, Dae Sun Jo, Yun-Kyung Kim, Byung-Wook Eun, Taek-Jin Lee, Jina Lee, Hyunju Lee, Ki Hwan Kim, Hye-Kyung Cho, Eun Young Cho, Jong-Hyun Kim
Clin Exp Pediatr. 2019;62(7):252-256.   Published online July 15, 2019
The Committee on Infectious Diseases of the Korean Pediatric Society recommended immunization schedule for children and adolescents aged 18 years or younger in the 9th (2018) edition of Immunization guideline. This report provides the revised recommendations made by the committee and summarizes several changes from the 2015 guideline. National immunization program (NIP) launched a human papillomavirus (HPV) immunization for girls...
Infection
Recommended immunization schedule for children and adolescents: Immunization Guideline (8th edition) released by the Korean Pediatric Society in 2015
Jong-Hyun Kim, Eun Hwa Choi, Su Eun Park, Yae-Jean Kim, Dae Sun Jo, Yun-Kyung Kim, Byung-Wook Eun, Jina Lee, Soo-Young Lee, Hyunju Lee, Ki Hwan Kim, Kyung-Hyo Kim
Clin Exp Pediatr. 2016;59(12):461-465.   Published online December 31, 2016

This report includes the recommended immunization schedule table for children and adolescents based on the 8th (2015) and revised 7th (2012) Immunization Guidelines released by the Committee on Infectious Diseases of the Korean Pediatric Society (KPS). Notable revised recommendations include: reorganization of the immunization table with a list of vaccines on the vertical axis and the corresponding age on the...

Recommended immunization schedule for children and adolescents: the Korean Pediatric Society, 2013
Dae Sun Jo, Jong-Hyun Kim, Eun Hwa Choi, Su Eun Park, Yae-Jean Kim, Yun Kyung Kim, Jina Lee, Byung Wook Eun, Soo Young Lee, Hyunju Lee, Ki Hwan Kim, Kyung-Hyo Kim
Clin Exp Pediatr. 2013;56(6):231-234.   Published online June 21, 2013

This article contains the recommended immunization schedule by the Committee on Infectious Diseases of the Korean Pediatric Society, updated in March 2013, when Haemophilus influenzae type b vaccine is now included in the National Immunization Program in Korea. It also includes catch-up immunization schedule for children and adolescents who are behind the recommended schedule. These schedules are a minor revision...

An overview of the national immunization policy making process: the role of the Korea expert committee on immunization practices
Hee Yeon Cho
Clin Exp Pediatr. 2012;55(1):1-5.   Published online January 31, 2012

The need for evidence-based decision making in immunization programs has increased due to the presence of multiple health priorities, limited human resources, expensive vaccines, and limited funds. Countries should establish a group of national experts to advise their Ministries of Health. So far, many nations have formed their own National Immunization Technical Advisory Groups (NITAGs). In the Republic of Korea,...

Original Article
The immunogenicity and reactogenicity of Td booster vaccination in Korean preadolescents, aged with 11-12 years old
Soo Young Lee, Ga Young Kwak, Hye Rin Mok, Jong Hyun Kim, Jae Kyun Hur, Kyung Il Lee, Park Joon Su, Sang Hyuk Ma, Hwang Min Kim, Jin Han Kang
Clin Exp Pediatr. 2008;51(11):1185-1190.   Published online November 15, 2008
Purpose : This study was undertaken to evaluate the immunogenicity and reactogenicity of Td booster immunization in early preadolescents of Korea. Methods : Healthy preadolescents, who had been vaccinated with 4 or 5 doses of DTaP vaccines until 6 years old age, were enrolled in this study from August 2006 to April 2007. Diphtheria and tetanus anti-toxoid antibodies in sera were...
Immunogenicity of 7-valent pneumococcal conjugate vaccine related to booster immunization in Korean children
So Eun Park, Hyunju Lee, Soo Young Lim, Kyung Hyo Kim
Clin Exp Pediatr. 2008;51(6):622-628.   Published online June 15, 2008
Purpose : The purpose of this study was to evaluate the immunogenicity of the booster immunization with pneumococcal conjugate vaccine in Korean children. Methods : Thirty-nine children aged 12-23 months who visited Kangnam CHA Hospital between September 2006 and December 2006 were enrolled. The children were divided into primary and booster groups depending on their vaccination status for the 7-valent pneumococcal...
Antibody prsistence after Haemophilus influenzae type b (Hib) primary vaccination and response to boosters in Korean children
Hyunju Lee, So Eun Park, Soo Young Lim, Kyong Min Choi, Hoan Jong Lee, Kyung Hyo Kim
Clin Exp Pediatr. 2007;50(5):449-456.   Published online May 15, 2007
Purpose : Antibody persistence after primary series of Haemophilus influenzae type b (Hib) vaccine and responses to boosters are seldom studied in Korean children. We performed this study to evaluate the antibody titer in relation to booster immunization of Hib vaccine in Korean children. Method : One hundred forty four children aged 12-23 months were enrolled in three university hospitals. The...
Review Article
Present status and prospects of Haemophilus influenzae type b(Hib) immunization
Kyung Hyo Kim
Clin Exp Pediatr. 2006;49(3):242-250.   Published online March 15, 2006
Haemophilus influenzae type b(Hib) conjugate vaccines prevent Hib disease in individuals and reduce the carriage and transmission of the organism in the community. The incidence of Hib disease has been decreased dramatically in a diverse range of countries through the use of a variety of conjugate vaccines and vaccine schedules. In some countries, the vaccine has caused a near-disappearance of...
Immunization of preterm and low birth weight infant
Su-Eun Park
Clin Exp Pediatr. 2006;49(1):14-17.   Published online January 15, 2006
Infants who are born prematurely or with low birth weight should be immunized at the same postnatal chronologic age. They should receive BCG, DTaP, IPV vaccines according to the same recommended schedule as full term infants. Hepatitis B vaccine schedule is modified when hepatitis B vaccine is administered a infant with birth weight less than 2,000 g. The recommended standard...
Case Report
A Case of Hemolytic Disease in a Newborn Due to Anti-Jkb
Dong-Kyun Park, Young-Min Kim, Chong-Woo Bae, Yong-Mook Choi, Woo-In Lee
Clin Exp Pediatr. 2003;46(7):718-721.   Published online July 15, 2003
The isoimmune hemolytic disease of newborn due to the incompatibility of minor blood groups is characterized by progressive neonatal hyperbilirubinemia and anemia caused by the IgG antibody transmitted from the mother to the fetus. Recently we had a case of hemolytic disease in a newborn due to anti-Jkb. There were no ABO and Rh(D) incompatibilities between mother and baby. The...
Original Article
MMR Immunization Rate and Related Factors - Findings from Repeated Surveys(1996, 1999) on Elementary School Students in Kyonggi Province, Korea -
Moran Ki, Moynghee Kim, Young-Jeon Shin, Boyoul Choi
Clin Exp Pediatr. 2001;44(4):375-388.   Published online April 15, 2001
Purpose : This study was carried out to obtain the immunization rate of MMR, and to know the related factors. Methods : Subjects of the study were 3,364 students of 8 elementary schools of Kyonggi province. Surveys accompanied with questionnaires were conducted in 1996 and 1999, respectively. Results : The salient features of the findings were as follows : The immunization rate...
Changes of Measles Specific IgG after Active Immunization of Measles in Korean Children
Young Kyoo Shin, Jae Kyun Yoon, Ji Tai Choung, Young Chang Tockgo
Clin Exp Pediatr. 1996;39(6):788-796.   Published online June 15, 1996
Purpose : Despite preventive measures, measles outbreaks ocurred in 1989, 1990 and 1994 in Korea. Especially, the proportion of immunized school aged children and adolescents was increased, and the reason was, in our opinion, primary and secondary vaccine failure after measles immunization. In this context, we attempted to evaluate the changes of measles specific IgG levels in various age groups of...
Epidemiologic Study during 1993 Measles Outbreaks in Seongnam Area
Soon Ki Kim, In Kyoo Yi, Seung Kyoo Han, Jun Hee Park, Yun Jeong Chang, Jong Woon Choi, Jeung Gyu Kim, Byong Kwan Son
Clin Exp Pediatr. 1995;38(2):180-188.   Published online February 15, 1995
Purpose : Although remarkable progress has been made in efforts to control measles since measles vaccines became available for use, the long-term success of their vaccination programmes has been questioned, with the worldwide resurgence of the disease. This resurgence has increased attention on the inadequacy of current immunization programmes. In 1993 there have been measles outbreaks in Seong-nam city located...
In Vitro Immunization-IV: Antibody Response of Mouse Splenocytes Grown in a Mixture of Conditioned Media, Thymocytes, and Bone Marrow Cells
Dong Soo Kim, Geun Woong Noh
Clin Exp Pediatr. 1992;35(7):902-908.   Published online July 15, 1992
We have previously reported several methods of in vitro immunization using different conditioned media, and the highest antibody titer was observed when a mixture of three conditioned media[PHA-stimulated adherent splenocytes conditioned medium (ASM-P), ASM-p-stimulated non-adherent splenocyte conditioned medium (NASM-A), ASM-P-stimulated thymocyte conditioned medium (TM-A)] was used. In this experiment, thymocytes and/or bone marrow cells was added instead of above conditioned media...
The Effec of Conditiond Media Cultued from the Thymocytes and the Splenocytes on the Regulation of Antibody Isotypes; In Vitro Immunization-III
Dong Soo Kim, Geun Woong Noh, Soon Hwan Oh
Clin Exp Pediatr. 1992;35(3):306-314.   Published online March 15, 1992
We had developed a method of in-vitro immunization to increase antibody titer using several cnditioned media which were developed from mouse splenocyts and thymocytes. Using fetal calf serum, the splenocytes of the mouse were divided into two types; adherent cells and non-adherent cells. We used PHA to stimulate the adherent cells to produce PHA-stimulated adherent cell conditioned medium (ACSM-P). Non-adherent...
Immune response induced by live attenuated varicella vaccine(Biken@) in children with acute lymphoblastic leukemia.
Hyo Seop Ahn, Joong Gon Kim
Clin Exp Pediatr. 1991;34(9):1255-1260.   Published online September 30, 1991
To determine the safety and efficacy of varicella vaccine, we studied 10 healthy children and 12 children in remission from acute lymphoblastic leukemia. They were immunized with the Oka strain of live attenuated varicella vaccine (Biken®). All the healthy children and 6 children with leukemia received the vaccine of 1,000 plaque-forming units (PFU), and 6 leukemic children received the vaccine of 500 PFU. The...
Case Report
A Case of Neonatal Hemolytic Disease due to Anti-c Isoimmunization
Hwan Sup Kang, Hyo Sup Joo, Chong Woo Bae, Suk Chul Kang, Chang Il Ahn
Clin Exp Pediatr. 1982;25(9):945-948.   Published online September 30, 1982
A 40 hours old female neonate was admitted to the Pediatric Ward of Kyung Hee Unive- rsity Hospital due to severe jaundice. Laboratory work up showed typical pictures of immune hemolytic anemia. But there was no incompatibility of ABO and Rh(D) systems between the baby and mother. Minor blood groups were examined by Reagent Red Cells Selectogen and Antigram. High titer (1 : 125) of...
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