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We experienced a 4 year girl with idiopathic precocious puberty treated with a long acting LHRH
analog (Buserelin). As an indction therapy she received LHRH analog for 6 months in subcutaneous
route. After then she was maintained by intranasal therapy for 6 months. One month after the
induction therapy began, we observed prepunbertal pattern of LHRH stimulation test and significant
suppression of 17B-estradiol level.... |