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Hypoglycemia due to Hyperinsulinism is associated with nesidioblastosis, islet cell hyperplasia or
adenoma.
We experienced two newborn infants suffering from recurrent attacks of hypoglycemia, they were
underwent a subtotal pancreatectomy for suspected islet cell dysmaturation syndrome. No tumor was
found, but histology revealed islet cell hyperplasia and nesidioblastosis.
After surgery one case who was treated with diazoxide, had persistent hypoglycemia but the other
showed normal glucose... |
