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A 9-year-old girl presented with primary hypothroidism have been followed by the development of hyperthyroidism. The diagnosis of primary hypothyroidism had been made by clinical manifestation, elavated serum thyroid-stimulating hormone level, antithyroglobulin antibody and antimicrosome antibody. Five and a quarter years later, the diagnosis of hyperthyroidism had been made by clinical maifestation such as enlargemetn of thyroid gland, tahcycardia, increased... |