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Original Article
Neurology
Effects of low-dose topiramate on language function in children with migraine
Seung-A Han, Eu Jeen Yang, Younghwa Kong, Chan-Uhng Joo, Sun Jun Kim
Clin Exp Pediatr. 2017;60(7):227-231.   Published online July 31, 2017
Purpose

This study aimed to verify the safety of low-dose topiramate on language development in pediatric patients with migraine.

Methods

Thirty newly diagnosed pediatric patients with migraine who needed topiramate were enrolled and assessed twice with standard language tests, including the Test of Language Problem Solving Abilities (TOPs), Receptive and Expressive Vocabulary Test, Urimal Test of Articulation and Phonology, and computerized speech laboratory...

Short term outcomes of topiramate monotherapy as a first-line treatment in newly diagnosed West syndrome
Gyu Min Lee, Kyung Suk Lee, Eun Hye Lee, Sajun Chung
Clin Exp Pediatr. 2011;54(9):380-384.   Published online September 30, 2011
Purpose

To investigate the efficacy of topiramate monotherapy in West syndrome prospectively.

Methods

The study population included 28 patients (15 male and 13 female children aged 2 to 18 months) diagnosed with West syndrome. After a 2-week baseline period for documentation of the frequency of spasms, topiramate was initiated at 2 mg/kg/day. The dose was increased by 2 mg/kg every week to a...

A study on the therapeutic effects of Topiramate according to the types of migraine
Jun Hwa Lee, Kyung Lae Cho
Clin Exp Pediatr. 2010;53(4):554-559.   Published online April 15, 2010
Purpose : The purpose of this study was to evaluate whether the therapeutic effects of topiramate differ according to the types of migraine. Methods : We recruited 38 children and adolescents with migraine who had been treated with topiramate. The effect of topiramate was evaluated on the basis of the change in the frequency of migraine attacks after treatment. Results : Among...
Case Report
Topiramate can reduce the number of episodic attacks in cyclic vomiting syndrome : a case report
Mi-Sun Yum, Keun Wook Bae, Su Jeong You, Tae Sung Ko
Clin Exp Pediatr. 2007;50(4):386-389.   Published online April 15, 2007
Cyclic vomiting syndrome (CVS) is a paroxysmal, recurrent vomiting disorder of unknown pathophysiology and target organ. It has been hypothesized that CVS shares the same mechanism as migraine. We describe here a 5-year-old boy with CVS characterized by episodic vomiting attacks. These recurrent vomiting episodes began at 3 years of age, occurred every month and lasted for 5 days at...
Original Article
Predictive value of cobalt chloride solution for hypohidrosis with topiramate
Hyuk Lee, Seung Hyun Lee, Sun Jun Kim
Clin Exp Pediatr. 2006;49(11):1180-1185.   Published online November 15, 2006
Purpose : The aims of this study were to verify the incidence of hypohidrosis and to determine the predictive value of noninvasive indicator test (NeurocheckTM) for sweating after administration of topiramate in newly diagnosed pediatric epileptic patients. Methods : A total of 46 epileptic patients (22 boys; 24 girls) on topiramate treatment were evaluated in this study at the Department...
Clinical Study of Effectiveness Topiramate in Children with Intractable Epilepsy
Young Mi Choi, Sa Jun Chung
Clin Exp Pediatr. 2001;44(1):62-67.   Published online January 15, 2001
Purpose : Topiramate(TPM) is a new anticonvulsant with multiple action mechanisms which should theoretically represent a wide therapeutic spectrum. However, there is still little clinical experience of its use in Asian children with epilepsy. Methods : The patients were total 96 children who were treated with more than 2 anticonvulsants but poorly controlled seizure activity. TPM was given as add-on therapy...
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