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Original Article
Expression of Tumor Suppression Gene in Childhood Cancer
Ji Eun Lee, Myung Ik Lee, Chang Soo Park
Clin Exp Pediatr. 1998;41(3):383-389.   Published online March 15, 1998
Purpose : Childhood cancer is closely related to the mutation of tumor suppressor gene. The mutant gene may evoke congenital anomaly and development of cancer. The common solid tumors in childhood are Wilms' tumor, retinoblastoma and neuroblastoma. The cytogenetic study has been performed. The cytogentic study revealed structural abnormality of chromosome in Wilms' tumor and retinoblastoma. The oncogene and mutation...
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