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Original Article
Association of HLA-G gene promoter haplotype with childhood IgA nephropathy in the Korean population
Hwan Hee Jung, Won Ho Hahn, Byoung Soo Cho, Sung Do Kim
Clin Exp Pediatr. 2010;53(4):548-553.   Published online April 15, 2010
Purpose : IgA nephropathy (IgAN) is the most commonly occurring form of chronic glomerulonephritis in pediatric cases.Human leukocyte antigen (HLA) genes have been implicated in various inflammatory and autoimmune diseases. The present study was conducted to investigate the association between 2 single nucleotide polymorphisms (SNPs) of the HLA-G gene and childhood IgAN. Methods : The authors analyzed and compared HLA-G gene...
Diagnostic Value of 99mTc-DMSA SPECT in Children with Urinary Tract Infection
Jae Won Choi, Sung Ho Cha, Byoung Soo Cho, Duk Yoon Kim
Clin Exp Pediatr. 1997;40(11):1559-1566.   Published online November 15, 1997
Purpose : The accurate identification of renal cortical defects in children with urinary tract infection is essential in reducing subsequent morbidity. Imaging of the kidneys with 99mTc-dimercaptosuccinic acid (DMSA) has been demonstrated as the sensitive method available for identification of renal cortical defects. Single photon emission computerized tomography(SPECT) has been suggested as a method by which the accuracy of identification of renal cortical defects can...
Renal Scarring in Relation to Vesicoureternal Reflux in Uriary Tract Infection
Kwang Sun Han, Dong Jin Choi, Sung Ho Cha, Byoung Soo Cho, Young Tae Ko, Sun Wha Lee
Clin Exp Pediatr. 1993;36(10):1402-1406.   Published online October 15, 1993
The vesicoureteral reflux (VUR) is frequently found among the patients with urinary tract infection (UIT) and some patients with VUR progress to reflux nephropathy. The presence of scarring at UIT is an important determinant in the selection of those at risk of progressive damage. 99m Technetium dimercaptosuccinic acid (99mTc-DMSA) is a renal scanning agent provides a good quality of renal image...
Clinical Studies of Henoch-Schölein Purpura Which was Considered as Acute Abdomen
Seong Young Jeong, Seong Yun Cho, Chio Heong Park, Seong Ho Cha, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1993;36(8):1124-1132.   Published online August 15, 1993
Henoch-Schölein purpura is a common pediatric disease presenting most frequently with skin, gastrointestinal, joint and renal manifestations. But in cases are infrequently only severe gastointestinal manifestations. It is hard to diagnose promptly and exactly. Clinical manifestations and laboratory findings were observed and analyzed in 20 cases with Henoch-Schölein purpura which were considered as acute abdomen, hospitalized at Kyung Hee university Hospital...
Atypical Presentation of Acute Glomerulonephritis
Hyun Ho Shin, Thy Hyung Park, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Moon Ho Yang
Clin Exp Pediatr. 1993;36(7):987-993.   Published online July 15, 1993
Form March 1982 to December 1991, 110 cases of typical post-streptococcal glomerulonephritis and 25 cases of Atypical acute glomerulonephritis were clinically investigated at Department of pediatrics, Kyung Hee University Hospital, and follwing Data were obtained. 1) Male to Femal ratio was 1.8:1 (Atypical AGN). Peak incidence was from 7 to 12 years. 2) The most common preceding infections were upper respiratory infection,...
Clinical Study and Availability of Ultrasonography in Hemorrhagic Cystitis
Jin Park, Chi Hyung Park, Chong Woo Bae, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Sun Wha Lee
Clin Exp Pediatr. 1992;35(12):1722-1727.   Published online December 15, 1992
Acute hemorrhagic cystitis characterized by gross hematuria and symptoms of bladder irritation occurs in children as a self-limited disease that must be differentiated from serious renal disease. We analyzed 22 cases of hemorrhagic cystitis which were managed in the Dept. of pediatrics, Kyung Hee university hospital and present the availability of bladder sonography for diagnosis of hemorrhagic cystitis and for follow-up. The...
Hypercalciuria Associated with Nephropathy (diagnosis by renal biopsy)
Hyun Ho Shin, Jae Yoon Kim, Chong Woo Bae, Sung Ho Cho, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Moon Ho Yang
Clin Exp Pediatr. 1992;35(11):1509-1513.   Published online November 15, 1992
Idiopathic hypercalciuria is defined as excessive urinary excretion of calcium in normocalcemia without any primary cause. We performed the sono-guided percutaneous renal biopsy for patients of recurrent hematuria, persistent microscopic hematuria, proteinuria and RBC cast to evaluate underlying nephropathy. We could obtained the following results 1) The age at the renal biopsy ranged from 3 years to 14 years. Sex ratio is 1.9:1...
A case of lipodystrophia centrifugalis abdominalis infantilis.
Kyu Young Lee, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Woo Young Sim, Choong Rim Haw, Moon Ho Yang
Clin Exp Pediatr. 1991;34(10):1452-1457.   Published online October 31, 1991
We report a case of lipodystrophia centrifugalis abdominalis infantilis in 24 month male. At age 18 months, his mother noticed a fairly well-defined depression of skin in the both inguinal and axillary area, which gradually spread centrifugally to the lower portion of abdomen and total inguinal and axillary region. The laboratory findings were unremarkable. Biopsy showed absense of subcutaneous fat in the affected area.
A case of nephrogenic diabetes insipidus due to vesicoureteral reflux.
Yong Bae Suh, Jong Yul Jeon, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1991;34(9):1299-1304.   Published online September 30, 1991
Nephrogenic diabetes insipidus is a disorder characterized by polydipsia and polyuria resulting from failure of the renal tubules and collecting ducts to respond to antidiuretic hormone despite elevated blood levels of antidiuretic hormone. We experienced a case of nephrogenic diabetes insipidus in 13 months-old girl probably secondary to vesicoureteral reflux grade IV. The clinical manifestations were extreme thirst, polydipsia and polyuria. Family history was nonspecific and...
A case of Bartter's syndrome.
Kyu Young Lee, Byoung Soo Cho, Hah Young Lee, Jay Bernstein
Clin Exp Pediatr. 1991;34(6):849-856.   Published online June 30, 1991
Bartter’s syndrome in characterized by renal potassium wasting, hypokalemic alkalosis, hyper- reninemia, normal blood pressure and resistance to the blood pressure augmenting effect of angioten- sin, accompanied by often hypomagnesemia and increased production of certain renal prostaglandins. The primary defect in this rare disorder is considered to be a renal tubular dysfunction. We had experienced a case of Bartter’s syndrome in 9 months old...
Clinical analysis and prognostic factors in Henoch-Schonlein purpura .
Ha Young Lee, Chong Sung Chung, Kyu Chul Choeh, Byoung Soo Cho, Young Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1991;34(5):682-690.   Published online May 31, 1991
This study was undertaken to evaluate the prognostic factors of recurrence and renal involvement in Henoch-Sch公nlein purpura. Total 110 cases of anaphylactoid purpura below 15 years of age who admitted to Pediatric Departmen of Kyung Hee University for 8 years from January 1st 1979 to December 31st 1986 were analyzed clinically and statistically. The results were obtained as follows. 1) The peak incidence of age was 4...
Bone mineral density of normal Korean children.
Kyu Young Lee, Byoung Yul Lim, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Seol Kim
Clin Exp Pediatr. 1991;34(5):605-613.   Published online May 31, 1991
The diagnosis of renal osteodystrophy and osteoporosis is established by clinical manifestations, biochemical laboratory tests, X-ray and bone scan but early diagnosis, determination of treatment of various metabolic bone diseases are not satisfied with any above methods. Dual energy X-ray absorptiometry (DEXA) has been shown to be a reliable, reproducible, and noninvasive way to assess bone mineral status. We evaluated the bone mineral density...
Comparison Study of Initial and Recurrent Intussuception in Children.
Eun Kyoung Sohn, Byoung Soo Cho, Sung Ho Cha, Chang Il Ahn, Soo Myung Oh
Clin Exp Pediatr. 1989;32(10):1353-1359.   Published online October 31, 1989
We performed statistcial evaluation on initial intussusception, 426 cases,and recurrent intussuscep- tion, 40 cases (28 children), recurred more than one time among 426 cases of initial intussusception which were managed in the depratment of pediatrics and the department of pediatric surgery at Kyung Hee University Hospital from Jan. 1983 to Dec. 1987. The results were as follows: 1) The peak incidence was found in less than...
The Clinical study of Acute Poisoning in Children.
Ji Ho Song, Sang Young Chung, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1989;32(10):1331-1336.   Published online October 31, 1989
A clinical study was performed on 145 cases of acute poisoning who were admitted in pediatric department of Kyung Hee University Hospital during the past 15 years from Jan. 1973 to Dec. 1987. The results are as follows; 1) There was no significant annual differences in frequency of poisoning, and the peak incindence in a year was in April and July (12.4%). 2) The sex ratio of...
Diagnostic Value of the Lung Perfusion Scan in Foreign body Aspiration.
Ki Hong Park, Chong Woo Bae, Byoung Soo Cho, Sa Joon Chung, Yong Mook Choi, Chang Il Ahn, Sun Wha Lee, Chang Il Cha
Clin Exp Pediatr. 1988;31(10):1301-1307.   Published online October 31, 1988
Lung perfusion scan was performed on 5 young children suspected as foreign body aspiration who had been admitted on the Department of Pediatrics, Kyung Hee University Hospital from May 1986 to January 1988. The results were as follows: 1) All children had been showed perfusion defect as compatible as acute obstructive lung disease by lung perfusion scan and foreign bodies in bronchial tree were proved on...
A Case of Myositis Ossificans Progressiva.
Yoeng Ho Ra, Sung Ho Cha, Byoung Soo Cho, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1988;31(2):271-275.   Published online February 28, 1988
A cases of Myositis ossificans progressiva in a 3 year-old girl who presented with hard mass in her right buttock and progressive hardening of muscles of her back and neck. The diagnosis was made on the basis of typical clinical features and characeristic radiologic findings. In addition to the cases report, a review of related literatures were discussed.
Clinico-Epidemiological Study on Leprosy Patients in Children.
Koo Jeoung Jung, Byoung Soo Cho, Sung Ho Cha, Sa Jun Chung, Chang Il Ahn, Do Seo Koo, Do Il Kim
Clin Exp Pediatr. 1987;30(7):769-776.   Published online July 31, 1987
Clinico-epidemiological study on 44 patients with leprosy in less than 20-year-old children visited to Institute for Leprosy Research, Korean Leprosy Control Association during past 9 years from January, 1978, to August, 1986 was carried out and the following results were obtained. 1) Age at time of visit was shown peak in the age group of 16-20 years (34 cases, 77%), but non in the age...
Significance of Brain CT in Children with Meningitig.
Myeong Yeon Lee, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1987;30(6):640-650.   Published online June 30, 1987
This study was undertaken to evaluate the significance of brain CT in children with meningitis. The findings of brain CT in 71 children with meningitis were evaluated in relation to the clinical outcome. We divided 71 cases into 5 groups according to clinical outcome on discharge, that is, Group I: Recovery. Group II: Discharge with improvement. Group III: Discharge with residual sequalae. Group IV:...
Electorcardiographic, M-mode and Two Dimensional Echocardiographic Findings in Kawasaki Syndrome.
In Hwa Lee, Byoung Soo Cho, Sung Ho Cha, Chang Il Ahn
Clin Exp Pediatr. 1986;29(11):1201-1214.   Published online November 30, 1986
This study was undertaken to evaluate the significance of the electrocardiography, M-mode and two dimensional echocardiography and to determine the extent of cardiac involvement in Kawasaki syndrome. The studies of laboratory tests, chest X-ray, electrocardiography, M-mode and two dimensional echocardiography were carried out in 30 subjects with Kawasaki syndrome admitted at K.H.U.H. from 1 st Jan. 1984 to 31th...
Clinical Analysis of Mesangial IgM Nephropathy in Childhood.
Joo Hong Cha, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1986;29(8):862-867.   Published online August 31, 1986
In order to clarify mesangial IgM nephropathy in childhood the author performed this study, for which 12 cases of mesangial IgM nephropathy demonstrated by Immunofluorescent technique were analyzed. The immunoglobulin deposited predominantly in mesangium was IgM, but also C3 deposited on most occasions. It was demonstrated that this groups of the patients with mesangial IgM nephropathy showed very similar picture...
Case Report
A Case of Recurrent Bacterial Meningitis Secondary to the Defect of Stapes Footplate.
Soon Hee Eom, Joo Hong Cha, Byoung Soo Cho, Sa Jun Chung, Chang Il Ahn, Chang Il Cha
Clin Exp Pediatr. 1986;29(7):779-783.   Published online July 31, 1986
With the dramatic lowering the mortality rate of bacterial meningitis since the introduction of antibacterial agents, multiple attacks of bacterial meningitis no longer are a curiosity. So multiple attacks of bacterial meningitis may be the only indication of the existence of an abnormal communication between the nasopharynx or ear and the meningeal space and such a communication must be found. We...
Original Article
A Clinicopathological Study on Renal Biopsies in Children.
Chung Hye Chu, Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1985;28(7):705-713.   Published online July 31, 1985
A clinical and histopathological study was made on 53 cases of ultrasonoguided renal biopsies in children who were admitted to pediatric ward of Kyung Hee University Hospital, from February 1, 1979 to March 31, 1984. The result were as follows: 1)The final diagnosis was confirmed by ultrasonoguided renal biopsy in this 53 cases and there was no severe complication (perirenal hematoma, renal...
Case Report
A Case of Periodic Paralysis.
In Hwa Lee, Sung Man Kim, Byoung Soo Cho, Sa Jun Chung, Chang II Ahn, Kyung Hoi Ahn
Clin Exp Pediatr. 1985;28(5):510-513.   Published online May 31, 1985
Periodic paralysis is a group of diseases of unknown cause characterized by recurrent attacks of weakness or paralysis of the limb muscles, accompanied by loss of deep reflexes and failure of the muscles to respond to electrical stimulation. We have experienced a case of periodic paralysis in a 8-year-old boy who had frequent attacks of flaccid paralysis of the trunk and...
A Case of Neonatal Group B Streptococcal Meningitis.
Hyuun Kil Yoon, Phil Joun Song, Kyu Chul Choi, Chung Hye Chu, Byoung Soo Cho, Sa Jun Chung
Clin Exp Pediatr. 1984;27(10):1011-1017.   Published online October 31, 1984
Since 1970, the group B streptococcus has become significant cause of neonatal septicemia and meningitis. Two clinically and epidemiologically distinct types of illness have been described among neonate and infants, that is early and late onset type. We have recently experienced a case of late onset group B streptococcal infection, presented as meningitis and confirmed by Slidex Strepto-Kit. We believe...
Original Article
Role of Lumbar Puncture in Children with First Febrile Convulsion.
Kyu Chul Choi, Byoung Soo Cho, Sa Jun Chung, Yong Mook Choi, Chang Il Ahn
Clin Exp Pediatr. 1984;27(7):718-724.   Published online July 31, 1984
To assess the role of lumbar puncture in the children with their first febrile convulsion, the results of lumbar puncture in 154 children for a 3-year period were reviewed. In the frequency of the causes of febrile convulsion, meningitis and encephalitis were the most common (34.4%) and upper respiratory tract infection was the next(26.0%). The comparison and observations between the...
Case Report
2 Cases of Congenital Asplenia Syndrome.
Hyo Sup Joo, Chung Hye Chu, Byoung Soo Cho, Kyoo Hwan Rhee, Sa Jun Chung, Chang Il Ahn
Clin Exp Pediatr. 1984;27(2):191-196.   Published online February 28, 1984
The asplenia syndrome is rare, characterized by congenital abscence of spleen, cardiovascular anomalies and other malformations or malpositions such as total or partial situs inversus, symmetrical lobulation of the liver and/or lung. Associated multiple complex cardiovascular anomalies include common atrioventricular canal, pulmonary stenosis or atresia, anomalous venous drainage and transposition of great vessels. Two-dimensional echocardiography allows the accurate non invasive...
A Case of 18p- Syndrome.
Jin Tae Kim, Byoung Soo Cho, Chang Hyo Lee, Chang Il Ahn, Kap Soon Ju
Clin Exp Pediatr. 1981;24(6):589-591.   Published online June 15, 1981
We have experienced a case of 18p- syndrome in 22 month old girl who had craniofacial anomaly such as microcephaly, hypertelorism, nystagmus, depressed nasal bridge, complete bilateral cleft palate, both ear canal stenosis and mental retardation. Chromosome culture revealed short arm deletion of chromosome 18 in E group. As far as we know, this case is the first report of...
Original Article
Brain Computerized Tomography (CT) in Clinical Pediatrics.
Byoung Soo Cho, Chang Il Ahn
Clin Exp Pediatr. 1981;24(5):415-422.   Published online May 15, 1981
The results of Brain CT in 93 children with seizure and or other neurologic problems are evaluated in relation to the age of onset, patients' history, final diagnosis & EEG. The overall incidence of abnormal scans were 78.5% in our series. Analysis of CT results showed that the incidence of abnormal scan was closely related to the following criteria. 1....
Case Report
3 Cases of so called MOYAMOYA Disease.
Byoung soo Cho, Shin Ae Yoo, Soo Woong Lee
Clin Exp Pediatr. 1980;23(12):1054-1059.   Published online December 15, 1980
The so called MOYAMOYA disease is characterized by idiopathic progressive bilateral occlusions of internal carotid arteries near the supraclinoid portion, with a distinctive picture of abnormal net like vessels in the base of the brain. The term MOYAMOYA is a Japanese expression for "PUFF OF A SMOKE", suggested by Suzuki & Takaku in 1969. We have experienced typical 3 cases...
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