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Case Report
Concomitant occurrence of Turner syndrome and growth hormone deficiency
Jung Yu, Ha Young Shin, Chong Guk Lee, Jae Hyun Kim
Clin Exp Pediatr. 2016;59(Suppl 1):S121-S124.   Published online November 30, 2016

Turner syndrome (TS) is a genetic disorder in phenotypic females that has characteristic physical features and presents as partial or complete absence of the second sex chromosome. Growth hormone deficiency (GHD) is a condition caused by insufficient release of growth hormone from the pituitary gland. The concomitant occurrence of TS and GHD is rare and has not yet been reported...

Original Article
Change in the height of Korean children and adolescents: analysis from the Korea National Health and Nutrition Survey II and V
Na Yung Ryoo, Ha Young Shin, Jae Hyun Kim, Jin Soo Moon, Chong Guk Lee
Clin Exp Pediatr. 2015;58(9):336-340.   Published online September 21, 2015

The mean adult height of Koreans has increased since nationwide anthropological measurements began in 1967. The objective of this study was to evaluate differences in heights of Korean late adolescents and young adults within and between the Second and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES II and V).


Koreans aged ≤22 years with available measurements of height were...

Case Report
Massive pulmonary hemorrhage in enterovirus 71-infected hand, foot, and mouth disease
Dong Seong Lee, Young Il Lee, Jeong Bae Ahn, Mi Jin Kim, Jae Hyun Kim, Nam Hee Kim, Jong Hee Hwang, Dong Wook Kim, Chong Guk Lee, Tae Won Song
Clin Exp Pediatr. 2015;58(3):112-115.   Published online March 20, 2015

Hand, foot, and mouth disease (HFMD) is an acute, mostly self-limiting infection. Patients usually recover without any sequelae. However, a few cases are life threatening, especially those caused by enterovirus 71 (EV71). A 12-month-old boy was admitted to a primary hospital with high fever and vesicular lesions of the mouth, hands, and feet. After 3 days, he experienced 3 seizure...

Original Article
Validation study of the Dinamap ProCare 200 upper arm blood pressure monitor in children and adolescents
Chong Guk Lee, Hyang Mi Park, Hye Jung Shin, Jin Soo Moon, Yeong Mi Hong, Nam Soo Kim, Il Soo Ha, Myeong Jin Chang, Kyeong Won Oh
Clin Exp Pediatr. 2011;54(11):463-469.   Published online November 30, 2011

To validate the Dinamap ProCare 200 blood pressure (BP) monitor against a mercury sphygmomanometer in children 7 to 18 years old in accordance with the 2010 International Protocol of European Society of Hypertension (ESH-IP2) and the British Hypertension Society (BHS) protocol.


Forty-five children were recruited for the study. A validation procedure was performed following the protocol based on the ESH-IP2 and...

Complex febrile convulsions: A clinical study
Jeong Sic Kang, Sa-Ra Kim, Dong Wook Kim, Tae Won Song, Nam Hee Kim, Jong Hee Hwang, Jin Soo Moon, Chong Guk Lee
Clin Exp Pediatr. 2009;52(1):81-86.   Published online January 15, 2009
Purpose : Febrile convulsions are classified into simple or complex types, the latter being characterized by increased risk of recurrence and progression to epilepsy. This study aimed to delineate the clinical characteristics of complex febrile convulsions. Methods : Between January 2003 and December 2006, 550 children were diagnosed with febrile convulsions at the Department of Pediatrics, Ilsan Paik Hospital. Their...
Prevalence and trends in obesity among Korean children and adolescents in 1997 and 2005
Kyungwon Oh, Myoung Jin Jang, Na Yeoun Lee, Jin Soo Moon, Chong Guk Lee, Myung Hwan Yoo, Young Taek Kim
Clin Exp Pediatr. 2008;51(9):950-955.   Published online September 15, 2008
Purpose : The objective of this study was to provide current estimates of the prevalence and examine trends of overweight and obesity in children and adolescents. Methods : Height and weight measurements from 183,159 (112,974 in 1997, 70,185 in 2005) children and adolescents aged 2 to 18 years were obtained via the 1997 and 2005 National Growth Survey. Obesity among...
An overview and the future of pediatric subspecialty board certification of the Korean Pediatric Society
Chong Guk Lee
Clin Exp Pediatr. 2008;51(6):555-558.   Published online June 15, 2008
Committee for pediatric subspecialty board certification of the Korean Pediatric Society (KPA) was established for the subspecialty certification and formal training programs in 2005. Pediatric allergy and pulmonology was the first pediatric subspecialty among 9 subdivisions of KPA to petition for the certification in 2006, and 7 additional subdivisions of KPA, pediatric cardiology, pediatric endocrinology, pediatric gastroenterology and nutrition, pediatric...
Review Article
Normative blood pressure references for Korean children and adolescents
Chong Guk Lee, Jin Soo Moon, Joong-Myung Choi, Chung Mo Nam, Soon Young Lee, Kyungwon Oh, Young Taek Kim
Clin Exp Pediatr. 2008;51(1):33-41.   Published online January 15, 2008
Purpose : It is now understood that blood pressure (BP) measurement in the routine pediatric examination is very important because of the relevance of childhood BP to pediatric health care and the development of adult essential hypertension. There hasn't been a reference table of BP for Korean children and adolescents up to now. This study was to make normative BP...
The methodology for developing the 2007 Korean growth charts and blood pressure nomogram in Korean children and adolescents
Soon Young Lee, Youn Nam Kim, Yeon Ji Kang, Myoung-Jin Jang, Jinheum Kim, Jin Soo Moon, Chong Guk Lee, Kyungwon Oh, Young Taek Kim, Chung Mo Nam
Clin Exp Pediatr. 2008;51(1):26-32.   Published online January 15, 2008
Purpose : This study was to provide the methods of developing the growth charts and the blood pressure nomogram among Korean children and adolescents. Methods : The growth charts were developed based on the data from the national growth surveys for children and adolescents in 1998 and 2005. The percentile charts were developed through two stages. At the first stage, the...
2007 Korean National Growth Charts: review of developmental process and an outlook
Jin Soo Moon, Soon Young Lee, Chung Mo Nam, Joong-Myung Choi, Bong-Keun Choe, Jeong-Wan Seo, Kyungwon Oh, Myoung-Jin Jang, Seung-Sik Hwang, Myung Hwan Yoo, Young Taek Kim, Chong Guk Lee
Clin Exp Pediatr. 2008;51(1):1-25.   Published online January 15, 2008
Purpose : Since 1967, The Korean Pediatric Society and Korean Government have developed Korean Growth Standards every 10 years. Last version was published in 1998. During past 40 years, Korean Growth Standards were mainly descriptive charts without any systematic nor statistical standardization. With the global epidemic of obesity, many authorities such as World Health Organization (WHO) and United States' Centers...
Original Article
Etiology of Community-acquired Bacteremia in Healthy Children
Hyung Tae Kim, Hyun Oh Jang, Jin Soo Moon, Seung Yeon Nam, Dong Wook Kim, Chong Guk Lee, Chong Rae Cho
Clin Exp Pediatr. 2005;48(7):716-722.   Published online July 15, 2005
Purpose : A full view of the spectrum of all bacterial diseases in healthy children is essential to the establishment of public health priorities. Accurate information on the relative importance of the various pathogens in terms of the age of the affected patients, the site of infection and the case fatality rate are valuable to the clinician in choosing antimicrobial...
A Case of Vitamin D-Dependent Rickets, Type 1
Ji Hye Hur, Chong Guk Lee, Chung Wook Sur
Accepted January 1, 1970  
"Rickets" is the term applied to impaired mineralization at epiphyseal growth plate, resulting in deformity and impaired linear growth of long bones. Rickets may arise as a result of vitamin D deficiency or abnormality in metabolism. Vitamin D-dependent rickets(VDDR) is rare autosomal recessive disorder in which affected individuals have clinical features of vitamin D deficiency. In 1961, Prader first described...
Original Article
A Clinical Study on Benign Convulsions with Mild Gastroenteritis
Jung Il Cho, Dong Wook Kim, Hyun Oh Jang, Jin Soo Moon, Seung Yeon Nam, Chong Guk Lee
Clin Exp Pediatr. 2004;47(12):1306-1311.   Published online December 15, 2004
Purpose : 'Benign convulsions with mild gastroenteritis(BCwMG)' is afebrile seizures associated with gastroenteritis without dehydration or electrolyte imbalance in young children aged almost 6 months to 3 years. Because seizures can occur repeatedly, patients can be misdiagnosed with epilepsy. Therefore, understanding the characteristics of this disease is thought to be important. This study was carried out to investigate the clinical...
Case Report
A Case of Congenital Malaria
Eun Jin Lee, Hyen Ho Chang, Chong Guk Lee, Chong Rae Cho
Clin Exp Pediatr. 2003;46(8):821-825.   Published online August 15, 2003
Malaria is known to have been eradicated for a few decades through the persistent efforts of the national health program in South Korea. However, malaria caused by Plasmodium vivax has started to reappear incidiously among military personnel near to the De-militarized Zone since 1993. From that time on the number of malarial cases have increased abruptly year by year. However,...
Two Cases of Castlema's Disease in Childern
Eun Ah Kim, Chong Guk Lee, Han Sung Kim
Clin Exp Pediatr. 2003;46(2):203-206.   Published online February 15, 2003
Castleman's disease is an atypical lymphoproliferative disorder of unknown origin. It has three histologic variants(hyaline vascular, plasma-cell, and mixed) and two clinical types(localized and multicentric). Some sufferers have constitutionalg symptoms and laboratory abnormalities such as anemia, hypoalbuminemia, hypergammaglobulinemia, and elevated erythrocyte sedimentation rate. The localized form is cured by complete surgical excision whereas the multicentric form is managed by prednisone...
Original Article
The Prevalent Rates of Abnormal Serum Aminotransferase Levels and Total Cholesterol Levels among Adolescents with Obesity
Hyun Oh Jang, Chong Guk Lee, Yun Ju Kang
Clin Exp Pediatr. 2002;45(12):1484-1490.   Published online December 15, 2002
Purpose : The purpose of this study was to look at prevalences of abnormal serum aminotransferase levels and abnormal serum total cholesterol levels among adolescents with obesity in Seoul area. Methods : Body mass index[BMI(kg/m2)], serum aspartate aminotransferase(AST) alanine aminotransferase(ALT), and total cholesterol levels were measured in 26,876 adolescents(male : 13,287, female : 13,589) of first grade of high school in...
Case Report
A Case of Transient Hyperphosphatasemia
Sung Kee Kim, Yong Won Park, Chong Guk Lee
Clin Exp Pediatr. 2000;43(6):856-860.   Published online June 15, 2000
We examined a male infant with transient increase in alkaline phosphatase(ALP) activity. The 25-month-old infant was admitted to a local hospital because of pneumonia of unknown etiology. Initial laboratory investigation revealed a serum ALP of 11,260U/L, which was comparable to that of bone isoenzyme on the electrophoresis pattern. There was no evidence of hepatitis, skeletal or intestinal diseases. The hyperphosphatasemia...
Two Cases of Pelizaeus-Merzbacher Disease
Ho Seok Kang, Se Wook Oh, Yong Won Park, Chong Guk Lee, Sang Woo Kim, Ghi Jai Lee
Clin Exp Pediatr. 2000;43(4):561-566.   Published online April 15, 2000
Pelizaeus-Merzbacher disease(PMD) is a rare sudanophilic leukodystrophy with a reduced number of mature oligodendrocytes as well as diffuse central nervous system hypomyelination(dysmyelination) due to abnormal synthesis of proteolipid protein. PMD is characterized with pendular nystagmus, stridor, delay in psychomotor development, hypotonia, ataxia, athetosis and extrapyramidal signs. Abnormal high signal intensity is shown in the entire white matter of cerebrum and...
A Case of Partial Monosomy lOq Syndrome
Young Kyoun Kim, Yong Won Park, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1999;42(6):863-867.   Published online June 15, 1999
It has been estimated that chromosomal aberrations account for 2.3% to 3% of normal pregnancies and of them 85% are aborted. Therefore, the survival rate of neonates with chromosomal aberrations are very low. Patients with partial deletion of the long arm of chromosome 10 are rare. We experienced a case of partial monosomy 10 in a 14-years-old girl. She showed...
A Case of Genital Prolapse in Premature Baby
Woong Kyu Choi, Seung Cheol Lee, Yong Won Park, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1998;41(2):281-284.   Published online February 15, 1998
Neonatal genital prolapse is very rare and is usually associated with meningomyelocele or other anomalies of the central nervous system. Synonyms of genital prolapse are sacropubic hernia, pelvic relaxation, and pelvic organ prolapse. There are two types of genital prolapse including vaginal prolapse and uterovaginal prolapse. We experienced a case of uterovaginal prolapse in a 30 day-old premature infant, which...
A Case of Lipoid Pneumonia with Hypercalcemia Caused by SqualelneⓇ Intake by Force
Young Kyoun Kim, Ho Suk Kang, Seung Cheol Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1997;40(12):1745-1749.   Published online December 15, 1997
Lipoid pneumonia is a chronic, interstitial, proliferative inflammation resulting from aspiration of lipoid material and occurs principally in debilated infants. We experienced a case of lipoid pneumonia with hypercalcemia in a 15 month-old boy who showed irritability, poor weight gain, cough, dyspnea, fatigue, diarrhea and pale face after ingestion of SqualeneⓇ(shark liver oil : 20-30 cap/day) by force for 2 months. Calcium preparation was also...
Original Article
Analysis of Urinary Mass Screening for Elemantary, Junior and High School Children Over a 8-year Period in Seoul
Chong Guk Lee, Dong Whan Lee, Sae Won Yang, Sung Ho Cha, Chang Ho Hong, Yong Mook Choi, Hyun Soon Lee, Sung Jae Seo
Clin Exp Pediatr. 1997;40(10):1347-1359.   Published online October 15, 1997
Purpose : The urinary mass screening program for the detection of proteinuria had been performed for a school age population in the city of Seoul since 1981. However, systematic evaluation for this program had never been done. We, therefore, designed a systematic evaluation in corporation with the Seoul School Health Center for students with proteinuria identified in the mass screening to determine the prevalence...
A Study of Radiocontrast Media Induced Nephrotoxicit
Chong Guk Lee, Jae Ho Cho, Se Wook Oh, Yong Won Park
Clin Exp Pediatr. 1996;39(4):503-511.   Published online April 15, 1996
Purpose : This study was aimed at determining whether tri-iodinated compounds with greater solubility and low osmolality, Na or meglumine ioxaglate(Hexabrix 320, Guerbet Lab., France) had deleterious effects on renal function after cardiac angiography for the evaluation of congenital heart disease(CHD) and determining whether correction of dehydration using iv hydration given before cardiac angiography were effective in prventing renal dysfunction. Methods...
Upper Limit of Normal Value for Antistreptolysin O Titer of Healthy Children in Seoul
Sung Ho Cha, Yong Mook Choi, Sei Won Yang, Dong Hwan Lee, Chong Guk Lee, Chang Ho Hong
Clin Exp Pediatr. 1995;38(8):1061-1068.   Published online August 15, 1995
Purpose : We have found somewhat high titer of antistreptolysin O (ASO) accidentally when we had delineated normal carrier rate of beta hemolytic streptococci in rural area of Kangwon Province in 1991(1). We would like to know upper limit of normal value of ASO and re-valuated results which might be changed with different geographic areas, age, and prevalent rate...
The incidence of complications in severely obese children.
Dong Hwan Lee, Chong Guk Lee, Chul Lee, Yong Seung Hwang, Sung Ho Cha, Yong Choi
Clin Exp Pediatr. 1991;34(4):445-453.   Published online April 30, 1991
The measurement of body weight, height and blood pressure, urine sugar, oral glucose tolerance test, S-GOT, S-GPT, cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol tests were made in 324 severely obese elementary, middle and high school students (218 boys and 106 girls) to know the incidence of complication in these children. . The results were as follow: 1) S-GOT or S-GPT were increased abnormally in 38.3% and fatty livers were...
A Case of Hemolytic Uremic Syndrome.
Seung Cheol Lee, Chong Guk Lee, Seong Hwan Kim, Sang Woo Kim, Hyun Soon Lee
Clin Exp Pediatr. 1990;33(8):1140-1147.   Published online August 31, 1990
A female child aged 7 months was admitted because of high fever, vomiting and stuporous conciousness and revealed to have hemolytic uremic syndrome. Anuria persisted 13 days and required peritoneal dialysis 4 times a day during the anuric period. Her kidney function recovered somewhat after dialysis but neurologic complications of marked hydrocephalus and brain atrophy remained.
The clinical evaluation for children with orthostatic proteinuria.
Chan Sung Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1989;32(11):1520-1525.   Published online November 30, 1989
Total of eighteen children with orthostatic proteinuria were evaluated for clinical characteristics. The development of renal or urologic diseases were monitored on these subjects for 1 year. The results were as following; 1) The number of children with transient orthostatic proteinuria and fixed orthostatic proteinuria were 7(39%) and 11(61%), respectively. 2) In children with fixed and reproducible orthostatic proteinuria, mild proteinuria were noted in 73% but no massive...
Analysis of Asymptomatic Proteinuria in School Children.
Chong Guk Lee, Tae Sub Shim, Dong Hwan Lee, Yong Soo Yun, Chang Jun Ko, Sa Jun Chung, Hyun Soon Lee, Sung Jae Suh, Pyung Nam Kim
Clin Exp Pediatr. 1989;32(9):1187-1194.   Published online September 30, 1989
Uriary mass screening program for the detection of proteinuria had been performed for a school- age population in the city of Seoul since 1981. Annually, about half million students, who comprised 3 different age group, corresponding to the averages of 11,14, and 17 years, had been examined. A systematic clinical evaluation was designed for students with proteinuria identified in the mass screening through ’87...
Periperal Plasma Renin Activity in Children with Normotensive Reflux Nephropathy.
Chong Guk Lee, Kwang Mann Ko
Clin Exp Pediatr. 1988;31(6):731-737.   Published online June 30, 1988
Peripheral renin activity was measured in 11 children with normotensive reflux nephropathy and 20 normal children to disclose the abnormality of the renin-angiotensin system in the patient group. 9 children among the patient group were allocated to single-dose captopril test for the assessment of the response to the test in patients with normotensive reflux nephropathy. 1. Contrary to the significant negative correlation between PRA and...
Management of Chronic Renal Failure in Childhood.
Chong Guk Lee
Clin Exp Pediatr. 1986;29(10):1060-1065.   Published online October 31, 1986
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