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Original Article
The Effect of Growth Hormone on Patients with Growth Hormone Deficiency and Idiopathic Short Stature
Jeong Cheol Kang, Yoon Suk Choi, In Kyong Choi, Ho Sung Kim, Duk Hee Kim
Clin Exp Pediatr. 2004;47(3):310-318.   Published online March 15, 2004
Purpose : This study was designed to evaluate the effect of growth hormones on children with growth hormone deficiency(GHD) or idiopathic short stature(ISS). Methods : Between January 1988 to July 2003, 45 patients(M26, F19) with GHD and 24 patients (M13, F11) with ISS were enrolled in this study. Height standard deviation score(Ht SDS) for chronological age(CA) and Ht SDS for bone...
Clinical Characteristics of Williams Syndrome
Choong Ho Shin, Ho Sung Kim, Sei Won Yang, Jung Yun Choi
Clin Exp Pediatr. 2001;44(4):443-449.   Published online April 15, 2001
Purpose : Williams syndrome(WS) is an autosomal dominant disorder resulting from a submicroscopic deletion of contiguous genes on the long arm of chromosome 7. We evaluated the physical, neurodevelopmental, and behavioral characteristics of children and adults with WS confirmed by fluorescence in situ hybridization. Methods : The clinically suspicious twelve cases with cardiac anomaly were confirmed as WS with fluorescence in...
Diagnostic Assessment of Pulmonary Atresia with Ventricular Septal Defect; Comparison of Echocardiogram with Cardiac Angiography
Jung Yun Choi, Jeong Jin Yu, Soo Jung Kang, Jae Seong Son, Young Mee Seo, Jin Young Song, Ho Sung Kim, Eun Jung Bae, Chung Il Noh, Yong Soo Yun
Clin Exp Pediatr. 2001;44(2):154-160.   Published online February 15, 2001
Purpose : Patients with pulmonary atresia with ventricular septal defects(PAVSD) have been a formidable surgical challenge. The source of pulmonary blood flow and vascular architecture are important in managing the surgical process. This study aimed to evaluate the usefulness of echocardiography in this process. Methods : This study was prospectively designed to define the role of echocardiography in PAVSD. Non-invasive evaluations...
Assessment of Myocardial Ischemia using Myocardial Perfusion Scan in Kawasaki Disease
Hong Ryang Gil, Jung Yun Choi, Myeong Ja Yoon, Soon Seong Park, Ho Sung Kim, Chung Il No, Yong Soo Yoon, Myung Chul Lee, Dong Soo Lee
Clin Exp Pediatr. 1999;42(2):211-220.   Published online February 15, 1999
Purpose : Myocardial scintigraphy has been reported to be useful in adults, but its usefulness in children is limited. This study was done to determine the feasibility and accuracy of 99mTc-MIBI SPECT(sestamibi, methoxy-isobutyl-isonitrarite myocardial single emission computed tomography, Dp-SPECT) after dipyridamole infusion to detect coronary obstructive lesions in Kawasaki disease (KD). Methods : Dp-SPECT was performed in 21 control(group 1), 8...
Microdeletion of Chromosome 7 in Williams Syndrome and Supravalvular Aortic Stenosis
Ho Sung Kim, Yoon Sung Kang, Kyung Hyo Kim, Young Mi Hong, Yong Soo Yun, Kwang Ho Lee
Clin Exp Pediatr. 1999;42(1):47-59.   Published online January 15, 1999
Purpose : Williams syndrome is characterized by supravalvular aortic stenosis, mental retardation and peculiar facial appearance. Its genetic etiology is considered to be a hemizygotic deletion in Chromosome 7q11.23, which includes the elastin gene. We examined the hemizygotic deletion of Chromosome 7q11.23 in 12 Korean Williams syndrome patients and 8 patients with isolated supravalvular aortic stenosis and performed deletion mapping...
Causes of Syncope in Children
Jae Young Lee, Chung Il Noh, Eun Jung Chun, Sun Sung Park, Myung Ja Yun, Hong Ryang Gil, Ho Sung Kim, Jung Yun Choi, Yong Su Yun
Clin Exp Pediatr. 1998;41(1):81-89.   Published online January 15, 1998
Purpose : Syncope is not rare and is caused by various conditions ranging from common physiologic derangements to life-threatening conditions. However, there are limited reports regarding syncope in children. We retrospectively analyzed our experiences of the syncope in children. Methods : Retrospective analysis of the medical records of patients with syncopal episodes between October 1985 and June 1996. Results : Sixty-eight patients(male; 36, female; 32,...
Interim Results of Single Stage Operation for Coarctation of Aorta with Large Ventricular Septal Defect in Infancy
Ho Sung Kim, Chung Il Noh, Yong Soo Yun, Jung Yun Choi, Jeong Ryul Lee, Yong Jin Kim, Joon Ryang Roh
Clin Exp Pediatr. 1997;40(9):1250-1257.   Published online September 15, 1997
Purpose : There are controversies in the operative methods of aorta with ventricular septal defect in infancy. Recent results of single stage operation for coarctation of aorta with intracardiac defects were regarded as comparable to staged operation. We evaluated our interim results after single stage operation for coarctation of aorta with large ventricular septal defect in infancy. Methods : Twenty six infants who had received...
Case Report
A Report of Familial Dilated Cardiomyopathy
Ee Kyung Kim, Jung Yun Choi, Chung Il Noh, Yong Soo Yun, Ho Sung Kim, Myung Hyun Lee, In Kyu Kim
Clin Exp Pediatr. 1997;40(6):857-861.   Published online June 15, 1997
Two families of dilated cardiomyopathy are reported. In the first family, two sons were affected. The elder child presented with congestive symptoms at the age of 5 months and was diagnosed to have dilated cardiomyopathy. The etiology of cardiomyopathy was thought to be idiopathic until his younger brother presented with near collapse at the age of 5 days and was diagnosed to have the...
Transcatheter Coil Closure of a Congenital Coronary Arterial Fistula
Hye Soon Kim, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Young Soo Yun
Clin Exp Pediatr. 1997;40(5):730-734.   Published online May 15, 1997
Congenital coronary artery fistulas are rare congenital heart anomalies. Surgical closure of these fistulas was the therapy of choice till recently. The recent development of a new accurate coil-delivery system has enabled us to embolize the vessels. Percutaneous transcatheter coil embolization is a safe and effective approach to treating coronary artery fistulas and should be considered as the best treatment...
Original Article
Intermediate Term Follow-up Results of Hypertrophic Cardiomyopathy in Children
Eun Jung Cheon, Chung Il Noh, Jae Young Lee, Sun Sung Park, Myung Ja Yun, Hong Ryang Kil, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1997;40(5):641-649.   Published online May 15, 1997
Purpose : Hypertrophic cardiomyopathy(HCMP) is a primary cardiac muscular disease with high risk of sudden cardiac death. This study is performed to understand the clinical features of children with HCMP. Methods : Retrospective analysis of the medical records of the patients diagnosed at Seoul National University Children's Hospital between October 1985 and June 1996 was done. Excluded the patients who had...
Experience of Stent Implantation in Branch Pulmonary Artery Stenosis of the Congenital Heart Diseas
Yong Soo Yun, Eun Jung Cheon, Ho Sung Kim, Chung Il Noh, Jung Yun Choi
Clin Exp Pediatr. 1997;40(3):343-351.   Published online March 15, 1997
Purpose : Branch pulmonary artery stenosis remains a clinically challenging lesion. Results of surgical angioplasty are rarely rewarding, and balloon angioplasty is not uniformly successful. So, endovascular stent has been applied recently to these lesions. But this new modality has not been full yevaluated. The aim of this study is to evaluate the short-term result of stent implantation in postoperative branch pulmonary artery stenosis. Methods :...
Case Report
A Case of Pulmonary Artery Sling Associated with Tracheobroncheal Hypoplasia
Yong Han Sun, Ho Sung Kim, Jung Il Noh, Jung Yun Cho, Yong Soo Yun
Clin Exp Pediatr. 1996;39(3):417-422.   Published online March 15, 1996
Pulmonary artery sling is a rare vascular anomaly wherein the left pulmonary artery arises from the right pulmonary artery and then traverses between the esophagus and the trachea toward the hilum of the left lung. Associated anomalies are common, particularly those of the tracheobronchial tree, which have been found in more than 50% of patients. Cardiovascular anomalies such as persistent...
Original Article
Clinical Stududy of CATCH 22
Hye Soon Kim, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Young Soo Yun, Jung Sun Kim, Jeong Wook Seo
Clin Exp Pediatr. 1995;38(12):1603-1609.   Published online December 15, 1995
The recognition that deletion of 22ql1 is a common cause of varied malformations and clinical disorders took more than a decade to achieve. Deletions of chromosome 22ql1 have been seen in association with DiGeorge syndrome (DGS) and velo¡ⓒ cardio-facial syndrome (VCFS). The large clinical overlap between DiGeorge syndrome and velo-cardio-facial syndrome suggest an aetiological connection. CATCH 22 synd¡ⓒrome is characterized...
Results of the Mechanical Valve Replacement in the Right Side of the Heart in Children
Hyeon Jin Park, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Yong Jin Kim
Clin Exp Pediatr. 1995;38(9):1220-1231.   Published online September 15, 1995
Purpose : We performed this study in order to evaluate the outcome of the mechanical valve replacement in the right side of the heart in children. Methods : Retrospective analysis of the clinical records of 26 patients who had undergone a right sided valve replacement between October 1986 and September 1992 at Seoul National University Children뭩 Hospital. Results : Twenty six children...
Clinical Observations of Transient Idiopathic Hypocalcemia
Jeong Nyun Kim, Mi Jung Park, Duk Hi Kim, Ho Sung Kim
Clin Exp Pediatr. 1995;38(9):1193-1200.   Published online September 15, 1995
Purpose : In concern of diagnosis and treatment of transient idiopathic hypocalcemia, a major cause of infantile, we studied the onset of age, clinical characteristics, laboratory findings, and duration of treatment and recovery of transient idiopathic hypocalcemia. Methods : The author observed 19 infants with transient idiopathic hypocalcemia who had been admitted to Yonsei university hospital due to convulsion for 4...
Sex Hormone Binding Globulin Levels in Children with Insulin Dependent Diabetes Mellitus
Duk Hi Kim, Mi Jung Park, Ho Sung Kim
Clin Exp Pediatr. 1995;38(7):963-969.   Published online July 15, 1995
Purpose : Sex hormone binding globulin(SHBG) is produced in liver and binds to testostero-ne and estradiol. Plasma SHBG levels are increased by estrogen and thyrotoxicosis and decreased by testostrone, insulin, growth hormone, prolactin, obesity and noninsulin dependent diabetes mellitus. SHBG levels in patients with NIDDM is known to be higher than normal, but SHBG levels in children with IDDM is controversial....
Double Chambered Right Ventricle-Review of Clinical Findings
Jin Young Song, Jun Tac Ko, Ho Sung Kim, Jung Il Rho, Jung Yeun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(7):914-921.   Published online July 15, 1995
Purpose : The DCRV is a cardiac anomaly in which the right ventricle is divided into two dif-ferent pressure chambers by aberrant hypertrophied muscle bundles arising from the lower infundibular septal region. DCRV may be associated with other congenital cardiac anomalies and surgical treatment is required because we know that this obstruction is progressive. In this report, we reviewed clinically...
Fetal Cardiac Malformation : types and associated anomalies
Ho Sung Kim, Jeong Wook Seo, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(6):811-818.   Published online June 15, 1995
Purpose : The relative incidence of fetal cardiac anomalies and associated extracardiac anomalies in Korean fetuses were studied. Methods : Findings in fetal echocardiography and autopsy were reviewed using 129 fetuses with cardiac anomalis detected at a gestational period under 38 weeks from 1991 Jan. to 1994 June. Results : The most common fetal cardiac anomaly was isolated atrial septal defect(28 cases...
Midterm Result after Transcatheter Occlusion of Patent Ductus Arteriosus with Rashkind PDA Umbrella Device
Chung Il Noh, Eun Sook Han, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1995;38(5):668-674.   Published online May 15, 1995
Purpose : To evaluate the appropriateness of the transcatheter occlusion with Rashkind um-brella occlusion device Methods : Among the 54 cases who had been tried transcatheter closure of patent ductus ar teriosus from January, 1992 till December, 1993 at Seoul National Univerity Children's Hospital, the first follow-up evaluation with Doppler echocardioram were done in 43 cases at the mean i-nterval of...
Case Report
Isolated Unilateral Pulmonary Vein Atresia
Yun Ae Jeon, Chung Il Noh, Ho Sung Kim, Jung Yun Choi, Yong Soo Yun, Woo Sun Kim, Je Geun Chi
Clin Exp Pediatr. 1995;38(3):409-416.   Published online March 15, 1995
We report four cases of unilateral pulmonary vein atresia without associated congenital intracardiac anomalies to illustrate a part of the clinical and radiological characteristics and its diagnosis. Pulmonary vein atresia was in right side in all cases. Narrowing of contralateral pulmonary vein and pure red cell anemia were combined in one cases. In four cases, initial presentations were hemoptysis and...
Original Article
Risk Factors for Hyperglycemia in Children with Leukemia Receiving L-asparaginase
Min Joong Kwon, Ho Sung Kim, Kir Young Kim, Duk Hi Kim
Clin Exp Pediatr. 1994;37(6):740-745.   Published online June 15, 1994
Hyperglycemia is a well-recognized side effect of L-asparaginase in remission induction therapy of acute lymphocytic leukemia. Since hyperglycemia has preceded fatal diabetic ketoacidosis or hyperosmotic nonketotic coma in some patients, early detection and treatment of this complication are important. We determined retrospectively the risk of hyperglycemia in 117 patients with leukemia who had received L-asparaginase (& prednisolone). The results were as...
Case Report
Candida Esophagitis in Infancy-A Report of 3 Cases
Ho Sung Kim, Youn Woo Kim, Jae Geon Sim, Beom Soo Park, Hoan Jong Lee, Joong Gon Kim, Jeong Kee Seo, Je Geun Chi
Clin Exp Pediatr. 1994;37(2):269-275.   Published online February 15, 1994
We experienced 3 cases of Candida esophagitis in infancy which were diagnosed by esophageal endoscopy, First case, 10 month-old boy with combined immune deficiency had suffered from oral thrush and poor feeding for more than 4 months. Esophageal endoscopy revealed multiple whitish creamy patches on the friable erythematous and necrotic mucosa of the esophagus, He was firstly treated with amphotericin-B...
Original Article
Cardiac Rhabdomyoma in Children-A Report of 26 Cases
Ho Sung Kim, Youn Woo Kim, Wun Jung Bae, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1994;37(1):61-69.   Published online January 15, 1994
We reviewed 26 cases of Cardiac rhabdomyoma in children which were diagnosed between 1986 and 1991 in Seoul National University Children's Hospital. Twenty-two cases were associated with tuberous sclerosis. Total tumor count was 58 and mean tumor count per patient was 2.23. Their Cardiac rhabdomyoma were diagnosed from fetal period through 12 years after birth. Median age was 9.5 months....
Case Report
Recurrent Rhinocerebral Mucormycosis - A Case Report
Ho Sung Kim, Jin Young Park, Bo Young Yun, Eun Sil Dong, Hee Young Shin, Hoan Jong Lee, Hyo Seop Ahn, Je Geun Chi, Myung Whun Sung
Clin Exp Pediatr. 1993;36(4):589-595.   Published online April 15, 1993
A case of recurrent rhinocerebral mucormycosis that has occurred during an induction chemotherapy for acute megakaryocytic leukemia in a 10 year-old boy is reported. He had suffered from high fever, proptosis, right eye ball pain and necrotic inflammation of hard palate during the chemotherapy of leukemia. CT scan of the paranasal sinus showed inflammatory change of right ethmoid and maxillary...
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