Clinical and Experimental Pediatrics

Original Article

Neurology

Long-term outcome in children with infantile epileptic spasms syndrome: a multicenter retrospective study in Korea

Sun Ah Choi, Minhye Kim, Hye Jin Kim, Woo Joong Kim, Byung Chan Lim, Ji Yeon Han, Hunmin Kim, Min-Jee Kim, Mi-Sun Yum, Jiwon Lee, Jeehun Lee, Hyewon Woo, Jon Soo Kim

Clin Exp Pediatr. 2026;69(5):386-393. Published online February 19, 2026

Web of Science 2 Crossref 2

Question: How have epilepsy and cognitive outcomes of children with infantile epileptic spasms syndrome (IESS) evolved over the past 20 years?
Finding: Approximately 78% of children developed chronic epilepsy, and one-third progressed to drug-resistant epilepsy, while 90% of them exhibited intellectual disabilities.
Meaning: Given the poor outcomes associated with IESS, consensus guidelines tailored to Korean clinical practice are required to ensure timely treatment and improve outcomes.

DOI: https://doi.org/10.3345/cep.2025.02089

Clinical Note

Genetics and Metabolism

Biallelic POLR3A variants cause Wiedemann-Rautenstrauch syndrome with atypical brain involvement

Byungseung Moon, Minhye Kim, Hye Jin Kim, Jae So Cho, Hey Joon Son, Byung Chan Lim, Ki Joong Kim, Jong Hee Chae, Soo Yeon Kim

Clin Exp Pediatr. 2023;66(3):142-144. Published online December 30, 2022

Web of Science 4 Crossref 3

DOI: https://doi.org/10.3345/cep.2022.01144

Original Article

Congenital Coronary Artery Fistula.

Hye Jin Kim, Yoo Ho Kim, Byeung Hae Ahn, Seung Hyup Kim, Wook Youm

Clin Exp Pediatr. 1988;31(3):381-385. Published online March 31, 1988

In a 9/12 year old male patient, the diagnosis of a right coronary artery fistula communicating with the right ventricle was made by noninvasive technique using two dimensional enchocardiography. The diagnosis was confirmed by aortography. Surgical correction was performed and the postoper- ative course was uneventful. A brief review of literatures was made.

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A Case of Dermatomyositis.

Hye Jin Kim, Tae Kyong Kim, Byeung Hae Ahn, Young Hee Yoo, Hyun Suk Lee

Clin Exp Pediatr. 1987;30(8):934-938. Published online August 31, 1987

A case of dermatomyositis in a 8-year-old girl is reported. She was admitted with chief complaint of progressive weakness of four extremities. The dignosis was made by typical clinical findings with aid of laboratory data and muscle biopsy finding. Her clinical symptoms and laboratory findings were improved markedly with oral steroid medication and physiotherapy. A brief review of related literatures has been done.

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