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Original Article
Risk factors for the occurrence and persistence of coronary aneurysms in Kawasaki disease
Soo-kyeong Jeon, Geena Kim, Hoon Ko, Joung-Hee Byun, Hyoung Doo Lee
Clin Exp Pediatr. 2019;62(4):138-143.   Published online November 22, 2018

Purpose: Prognostic factors of coronary aneurysms in Kawasaki disease have been investigated in many studies. The aim of this study was to identify risk factors associated with early and late coronary artery outcomes in treated patients with Kawasaki disease. Methods: A total of 392 patients diagnosed with Kawasaki disease from January 2012 to December 2015 in Pusan National University Children’s Hospital...
Nephrology (Genitourinary)
Acute tubular necrosis as a part of vancomycin induced drug rash with eosinophilia and systemic symptoms syndrome with coincident postinfectious glomerulonephritis
Kyung Min Kim, Kyoung Sung, Hea Koung Yang, Seong Heon Kim, Hye Young Kim, Gil Ho Ban, Su Eun Park, Hyoung Doo Lee, Su Young Kim
Clin Exp Pediatr. 2016;59(3):145-148.   Published online March 31, 2016

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare and potentially fatal condition characterized by skin rash, fever, eosinophilia, and multiorgan involvement. Various drugs may be associated with this syndrome including carbamazepine, allopurinol, and sulfasalazine. Renal involvement in DRESS syndrome most commonly presents as acute kidney injury due to interstitial nephritis. An 11-year-old boy was referred to...

Clinical features and short-term outcomes of pediatric acute fulminant myocarditis in a single center
Eun Young Lee, Hae Lyoung Lee, Hyung Tae Kim, Hyoung Doo Lee, Ji Ae Park
Clin Exp Pediatr. 2014;57(11):489-495.   Published online November 30, 2014

The aims of this study were to document our single-center experience with pediatric acute fulminant myocarditis (AFM) and to investigate its clinical features and short-term outcomes.


We performed a retrospective chart review of all children <18 years old who were diagnosed with AFM between October 2008 and February 2013. Data about patient demographics, initial symptoms, investigation results, management, and outcomes between...

Outcomes of the arterial switch operation in complete transposition of the great arteries
Min Jung Cho, Ji Ae Park, Hyoung Doo Lee, Si Chan Sung, Ki Seok Choo
Clin Exp Pediatr. 2009;52(8):910-916.   Published online August 15, 2009

Purpose:The arterial switch operation (ASO) has become the preferred procedure for the surgical management of transposition of the great arteries (TGA). We conducted a retrospective evaluation of our experience in 30 patients seen from January 2003 to July 2008, in order to determine outcomes and related risk factors after the arterial switch operation. Methods:Patients charts, surgical reports, and echocardiograms were retrospectively reviewed. And...
Case Report
A case of hepatopulmonary syndrome in a child with fatty liver disease secondary to hypopituitarism after craniopharyngioma resection
Sun Ju Im, Hyun Seok Park, Hyoung Doo Lee, Jae Hong Park, Hee Ju Park
Clin Exp Pediatr. 2007;50(8):794-798.   Published online August 15, 2007
Hepatopulmonary syndrome is a triad that includes: hepatic dysfunction, intrapulmonary vascular dilatation and abnormal arterial oxygenation. The incidence of intrapulmonary vascular dilatations, in adults with end-stage liver disease, has been reported to be 13% to 47%, however the incidence in children is unclear and the cases in Korean children have never been reported. The hepatopulmonary syndrome may occur as a...
Original Article
Early and mid-term results of pulmonary valve reconstruction in surgical repair of tetralogy of Fallot; comparison with other techniques of right ventricular outflow reconstruction
Sheng Wen Wang, Young Seok Lee, Si Ho Kim, Tae Hong Kim, Ji Eun Ban, Hyoung Doo Lee, Yun Hee Chang, Si Chan Sung
Clin Exp Pediatr. 2006;49(6):635-642.   Published online June 15, 2006
Purpose : The purpose of this study is to determine whether the new pulmonary valve reconstruction technique prevents short-term postoperative pulmonary regurgitation and improves early and mid-term clinical outcome. Methods : We reviewed postoperative echocardiographic variables and chest X-ray films from 31 patients who had undergone valve reconstruction(pulmonary valve reconstruction group : PVR) for the repair of TOF between April 2000...
Clinical Lecture
Pulmonary Insufficiency after Repair of Tetralogy of Fallot : Prevention and Indications of Pulmonary Valve Replacement
Hyoung Doo Lee
Clin Exp Pediatr. 2003;46(4):315-318.   Published online April 15, 2003
Original Article
Intraarterial Catheter-directed Urokinase Infusion for Femoral Artery Thrombosis after Cardiac Catheterization in Infants and Children
Hyoung Doo Lee
Clin Exp Pediatr. 2002;45(11):1397-1402.   Published online November 15, 2002
Purpose : One of the major complication of arterial catheterization is the thrombosis of the iliac or femoral arteries. Tissue loss following femoral artery catheterization is rare. However long- term sequelae such as impaired limb growth and future impairment of vascular access, are also important in pediatric cardiac patients. But standard methods to treat thrombotic complication of arterial catheterization in...
Clinical Efficacy of Selective Fetal Echocardiography
Su Young Hong, Ji Eun Ban, Young Seok Lee, Hyoung Doo Lee
Clin Exp Pediatr. 2001;44(10):1127-1134.   Published online October 15, 2001
Purpose : The aims of this study was to assess the indication, diagnostic, accuracy and prognostic influence of fetal echocardiography. Methods : From 1995 to 1999, 283 pregnancies were evaluated with fetal echocardiography at Dong-A University Hospital. We reviewed medical records included indication, fetal echocardiographic findings, postnatal echocardiographic findings, methods of treatment and outcome of prenataly diagnosed patients. Results : Family...
Case Report
A Case Successfully Treated by Local Low-dose Urokinase Infusion in Neonate with Blalock-Taussig Shunt Partially Occluded by Thrombus
Yong Chan Park, Hyoung Doo Lee, Gyu Tae No
Clin Exp Pediatr. 2000;43(10):1395-1398.   Published online October 15, 2000
For some cyanotic children with deficient pulmonary blood flow, the Blalock-Taussig shunt is a life-saving or temporizing form of palliation. Extensive experience has been gathered, and mortality and morbidity as well as the incidence of shunt stenosis and thrombosis have significantly decreased. However, even nowadays, the most frequently encountered complication excluding mortality in early postoperative course is occlusion of the...
Original Article
Postoperative Doppler Echocardiographic Study of Total Anomalous Pulmonary Venous Return
Nam Cheol Cho, Hyoung Doo Lee, Si Chan Sung
Clin Exp Pediatr. 1999;42(12):1683-1688.   Published online December 15, 1999
Purpose : We conducted this study to evaluate the efficacy of Doppler study by examining obstruction at the site of anastomosis in patients with total anomalous pulmonary venous return(TAPVR). Methods : Retrograde analysis of the postoperative echocardiography results was done in 14 patients with simple TAPVR, who were operated at Dong-A University Hospital from January 1993 to July 1998. The peak...
Case Report
One Case of Congenital Complete Atrioventricular Block Diagnosed by Fetal Echocardiography
Eun Jung Kim, Tae Hoon Kang, Hyoung Doo Lee
Clin Exp Pediatr. 1997;40(4):567-571.   Published online April 15, 1997
Congenital complete atrioventicular block is uncommon which has a heterogenous etiology. According to recent studies, about one-third of the mothers of the patients who were diagnosed as congenital complete atrioventricular block, had symptoms or signs of connective tissue disease. Even though the outlook is usually regarded as favorable, the mortality is highest in the neonatal period, much lower during childhood...
Original Article
Transcatheter Closure of Patent Ductus Arteriosus with the Rashkind PDA Occluder System
Hyoung Doo Lee
Clin Exp Pediatr. 1997;40(1):63-68.   Published online January 15, 1997
A Clinical Study of Interrupted Aortic Arch
Myoung Dong Shin, Tae Hun Kang, Hyoung Doo Lee, Si Chan Sung
Clin Exp Pediatr. 1995;38(10):1349-1355.   Published online October 15, 1995
Purpose : We conducted this study to determine the clinical manifestations and prognostic factors of interrupted aortic arch(IAA). Methods : We performed retrospective clinical study with chart review in 9 infants who were diagnosed as IAA between January, 1993 and December, 1994. Results : Infants with IA were from 7 days to 92 days of age. Among them, 6 cases were type...
A Clinical Study of Infants and Children with Urinary Tract Infection.
Hyoung Doo Lee, Chan Yung Kim
Clin Exp Pediatr. 1989;32(12):1706-1714.   Published online December 31, 1989
Clinical, bacteriologic and radiologic studies were performed in 63 infants and children with urinary tract infection who were admitted to Department of Padiatrics, Pusan National University Hospital from March 1982 to February 1988. The results were summarized as follows: 1) UTI was more prevalent in infancy and early childhood (71.4%). Sex distribution was similar in all age group, and male was more prevalent in infancy and...
A Case of Child Desquamative Interstitial Pneumonia.
Woo Taek Kim, Hyoung Doo Lee, Yung Tak Lim, Hee Joo Jeon, Hee Joo Park, Chan Yung Kim
Clin Exp Pediatr. 1989;32(1):92-100.   Published online January 31, 1989
Desquamative interstitial pneumonia (DIP) is a variant of idiopathic interstitial pneumonias, but characteristicalIy has massive desquamation and proliferation of alveolar cells into the distal air space with minimal fibrosis of the alveolar wall. DIP seems to have better response to corticosteroid and benign prognosis than idiopathic interstitial pneumonia. We experienced one case of 6-year old girl who showed typical picture of DIF on lung...
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