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Advancing pediatric health: the multifaceted scope of Clinical and Experimental Pediatrics
Jin Hee Oh, Man Yong Han
Clin Exp Pediatr. 2023;66(4):171-172.   Published online March 29, 2023
Clinical and Experimental Pediatrics (CEP) is a journal that specializes in pediatric research topics. It covers a wide range of research areas, including basic research, translational research, and research related to improving pediatric health and diseases. CEP also focuses on the coordination of societal structures and processes that orchestrate pediatric health and disease throughout society, and the parallel relationship between regional characteristics and globalization. The journal intends to continue promoting pediatric health through relentless efforts and the discovery of new research areas.
Original Article
Cardiology
Prediction of nonresponsiveness to medium-dose intravenous immunoglobulin (1 g/kg) treatment: an effective and safe schedule of acute treatment for Kawasaki disease
Kyung Pil Moon, Beom Joon Kim, Kyu Jin Lee, Jin Hee Oh, Ji Whan Han, Kyung Yil Lee, Soon Ju Lee
Clin Exp Pediatr. 2016;59(4):178-182.   Published online April 30, 2016
Purpose

Medium-dose (1 g/kg) intravenous immunoglobulin (IVIG) is effective in the majority of patients with Kawasaki disease (KD) but some patients who do not respond to medium-dose IVIG are at high risk for the development of coronary artery lesions (CALs). The purpose of this study was to identify the clinical predictors associated with unresponsiveness to medium-dose IVIG and the development of...

Usefulness of anterior uveitis as an additional tool for diagnosing incomplete Kawasaki disease
Kyu Jin Lee, Hyo Jin Kim, Min Jae Kim, Ji Hong Yoon, Eun Jung Lee, Jae Young Lee, Jin Hee Oh, Soon Ju Lee, Kyung Yil Lee, Ji Whan Han
Clin Exp Pediatr. 2016;59(4):174-177.   Published online April 30, 2016
Purpose

There are no specific tests for diagnosing Kawasaki disease (KD). Additional diagnostic criteria are needed to prevent the delayed diagnosis of incomplete Kawasaki disease (IKD). This study compared the frequency of coronary artery lesions (CALs) in IKD patients with and without anterior uveitis (AU) and elucidated whether the finding of AU supported the diagnosis of IKD.

Methods

This study enrolled patients diagnosed...

Baseline heart rate variability in children and adolescents with vasovagal syncope
Sun Hee Shim, Sun-Young Park, Se Na Moon, Jin Hee Oh, Jae Young Lee, Hyun Hee Kim, Ji Whan Han, Soon Ju Lee
Clin Exp Pediatr. 2014;57(4):193-198.   Published online April 30, 2014
Purpose

This study aimed to evaluate the autonomic imbalance in syncope by comparing the baseline heart rate variability (HRV) between healthy children and those with vasovagal syncope.

Methods

To characterize the autonomic profile in children experiencing vasovagal syncope, we evaluated the HRV of 23 patients aged 7-18 years and 20 healthy children. These children were divided into preadolescent (<12 years) and adolescent groups....

Case Report
Congenital central I42hypoventilation syndrome combined with Hirschsprung disease diagnosed in the neonatal period
Jin Hyun Choi, Jin Hee Oh, Jong-Hyun Kim, Dae Kyun Koh, Seung-Chul Hong
Clin Exp Pediatr. 2006;49(4):446-450.   Published online April 15, 2006
Congenital central hypoventilation syndrome (CCHS) or Ondine's curse is a very rare sleep disorder that is the result of a congenital failure of the autonomic control of ventilation caused by insensitivity of the chemoreceptor to hypercapnea during sleep. Gastrointestinal motility disorders, particularly a congenital megacolon (Hirschsprung disease) is often combined with CCHS. This combination can be explained by a defect...
Giant Coronary and Axillary Aneurysms in an Infant with Kawasaki Disease Associated with Thrombocytopenia
Sei Young Seo, Jin Hee Oh, Jong-Hyun Kim, Ji-Whan Han, Kyung-Yil Lee, Dae Kyun Koh
Clin Exp Pediatr. 2005;48(8):901-906.   Published online August 15, 2005
Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Yet the etiology of KD is still unknown and diagnosis depends on the exclusion of other diseases and the clinical manifestations meeting the defined criteria. Young infants frequently show atypical clinical courses and are frequently complicated with coronary aneurysms. Some cases show thrombocytopenia, which is known as...
A Case of Congenital Nephrogenic Diabetes Insipidus Confirmed by Gene Analysis
Eun Young Cho, Jin Hee Oh, Dae Kyun Koh
Clin Exp Pediatr. 2005;48(6):669-674.   Published online June 15, 2005
Nephrogenic diabetes insipidus (NDI) is a disorder in which the secretion of antidiuretic hormone is normal, but the response of the renal collecting tubules to vasopressin is impaired. Compared with acquired NDI (a-NDI), which is secondary to chronic bilateral incomplete urinary tract obstruction with hydronephrosis, congenital NDI (c-NDI) is a very rare heritable disorder that usually follows the X- linked...
A Case of Spinal Cord Injury without Radiographic Abnormality
Seoung Joon Kim, Dae Kyun Koh, Jin Hee Oh, Jong Hyun Kim, Jung Soo Jun
Clin Exp Pediatr. 2004;47(11):1228-1231.   Published online November 15, 2004
A spinal cord injury without radiographic abnormality(SCIWORA) was defined by Pang and Wilberger in 1982 as the "objective signs of myelopathy as a result of trauma" in which no evidence of fracture, subluxation, or instability on plain radiographs, or computed tomography is demonstrable. Inherent elasticity of the vertebral column in infants and young children, among other age-related anatomical peculiarities, render...
A Case of Epidural Emphysema Caused by Vigorous Coughing
Hye Rin Mok, Jin Hee Oh, Dae Kyun Koh
Clin Exp Pediatr. 2004;47(9):1013-1015.   Published online September 15, 2004
A 13-year-old boy was admitted via emergency room with dyspnea after vigorous coughing. Subcutaneous emphysema was palpated on both eyelids and around the neck. Breathing sound was slightly wheezy. On initial chest roentgenogram no parenchymal lesion or pneumothorax except subcutaneous emphysema on the thoracic wall was found. On the second day of hospitalization he showed agitation much more severe than...
Aplastic Crisis Secondary to Parvovirus B19 Infection
Yang Joon Park, Dae Kyun Koh, Jin Hee Oh
Clin Exp Pediatr. 2003;46(11):1139-1142.   Published online November 15, 2003
Human parvovirus(HPV) B19 infection causes erythema infectiosum in children, sometimes red cell aplastic crisis with hemolytic anemia and chronic bone marrow failure in immunocompromised hosts. HPV B19 is directly cytotoxic for erythroid progenitor cells and inhibits erythropoiesis. Infrequently, HPV B19 inhibits hematopoiesis of three cell lineages and causes transient pancytopenia in patients with hemolytic disorders. We report three patients with...
Original Article
Childhood Obstructive Sleep Apnea Syndrome : Clinical and Polysomnographic Findings
Yang Jun Park, Dae Kyun Koh, Jin Hee Oh, Soo Jung Lee
Clin Exp Pediatr. 2001;44(7):786-795.   Published online July 15, 2001
Purpose : Although pediatricians may see a lot of patients with clinically suspected obstructive sleep apnea syndrome(OSAS), the actual incidence, clinical and polysomnographic manifestations of OSAS in children have not well been recognized and reported cases are rare. The objective of this study was to evaluate the efficacy of polysomnography in the diagnosis of OSAS in children and to analyze...
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