Clinical and Experimental Pediatrics

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Original Article

The corrected QT (QTc) prolongation in hyperthyroidism and the association of thyroid hormone with the QTc interval

Ye Seung Lee, Joong Wan Choi, Eun Ju Bae, Won Il Park, Hong Jin Lee, Phil Soo Oh

Clin Exp Pediatr. 2015;58(7):263-266. Published online July 22, 2015

Crossref 21

Purpose

Ventricular repolarization is assessed using the QT interval corrected by the heart rate (QTc) via an electrocardiogram (ECG). Prolonged QTc is associated with an increased risk of arrhythmias and cardiac mortality. As there have been few reports regarding the effects of hyperthyroidism on ventricular repolarization, we studied the association between serum free thyroxine (free T4 [fT4]) and thyroid stimulating hormone...

DOI: https://doi.org/10.3345/kjp.2015.58.7.263

Case Report

Identification of a novel mutation in a patient with pseudohypoparathyroidism type Ia

Ye Seung Lee, Hui Kwon Kim, Hye Rim Kim, Jong Yoon Lee, Joong Wan Choi, Eun Ju Bae, Phil Soo Oh, Won Il Park, Chang Seok Ki, Hong Jin Lee

Clin Exp Pediatr. 2014;57(5):240-244. Published online May 31, 2014

Crossref 3

Pseudohypoparathyroidism type Ia (PHP Ia) is a disorder characterized by multiform hormonal resistance including parathyroid hormone (PTH) resistance and Albright hereditary osteodystrophy (AHO). It is caused by heterozygous inactivating mutations within the Gs alpha-encoding GNAS exons. A 9-year-old boy presented with clinical and laboratory abnormalities including hypocalcemia, hyperphosphatemia, PTH resistance, multihormone resistance and AHO (round face, short stature, obesity, brachydactyly...

DOI: https://doi.org/10.3345/kjp.2014.57.5.240

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