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Original Article
CD4+/CD8+ T lymphocytes imbalance in children with severe 2009 pandemic influenza A (H1N1) pneumonia
Ji Eun Kim, Siegfried Bauer, Kyong Suk La, Kee Hyoung Lee, Ji Tae Choung, Kyoung Ho Roh, Chang Kyu Lee, Young Yoo
Clin Exp Pediatr. 2011;54(5):207-211.   Published online May 31, 2011
Purpose

This study was conducted to investigate the immune responses of children with moderate and severe novel influenza A virus (H1N1) pneumonia, and to compare their clinical and immunological findings with those of control subjects.

Methods

Thirty-two admitted patients with H1N1 pneumonia were enrolled in the study. The clinical profiles, humoral and cell-mediated immune responses of the 16 H1N1 pneumonia patients who were...

Case Report
Isolated pulmonary cryptococcosis in an immunocompetent boy
Siegfried Bauer, Ji Eun Kim, Kyong Suk La, Young Yoo, Kee Hyoung Lee, Sang Hee Park, Ji Tae Choung, Chul Whan Kim
Clin Exp Pediatr. 2010;53(11):971-974.   Published online November 30, 2010

Pulmonary cryptococcosis is rare in immunocompetent subjects. Here, we present the case of a 16-year-old boy who was referred to our pediatric department for the management of multiple consolidations detected on chest radiography, which was routinely performed when the patient was being evaluated for an ankle fracture. Fine needle aspiration biopsy was performed, and the definitive diagnosis was established as...

Original Article
Effects of inhaled corticosteroids on bone mineral density and bone metabolism in children with asthma
Ic Sun Choi, Jung Hye Byeon, Seung Min Lee, Kyong Suk La, Yeon Joung Oh, Young Yoo, Kee Hyoung Lee, Ji Tae Choung
Clin Exp Pediatr. 2009;52(7):811-817.   Published online July 15, 2009
Purpose : Inhaled corticosteroids (ICS) are used as first-line agents for the treatment of persistent asthma; however, their use is accompanied by apprehension of potential systemic adverse effects. This study aimed to assess the effects of ICS on bone mineral density (BMD) and bone metabolism in children with asthma. Methods : From February 2008 to September 2008, 26 asthmatic children treated...
Case Report
Three cases of pulmonary and/or intestinal tuberculosis in adolescents
Jung Hye Byeon, Yoon Lee, Jin Chul Lee, Young Yoo, Kee Hyoung Lee, Kwang Chul Lee, Ji Tae Choung, Soo Youn Ham, Chul Whan Kim
Clin Exp Pediatr. 2007;50(11):1134-1138.   Published online November 15, 2007
Since the tuberculosis (TB) in adolescents has unique clinical characteristics, special attention should be paid to this age group. Adolescents are more susceptible to developing TB disease and more likely to have cavitary pulmonary disease. Also, adolescent patients with TB more frequently present with extrapulmonary disease. We report three adolescents with active pulmonary and/or intestinal TB: one had pulmonary and...
Original Article
Health and risk taking behaviors of freshmen in college
Hong Ki Ko, Jae Joon Han, Yoon Lee, Young Yoo, Kee Hyoung Lee, Ji Tae Choung, Sang Hee Park
Clin Exp Pediatr. 2006;49(10):1042-1049.   Published online October 15, 2006
Purpose : This study was conducted to survey the preliminary data on risk behaviors and to identify the factors that prevent risk-behaviors in late adolescence. Methods : Freshmen(n=1,297) beginning the first semester in Korea University, Seoul, Korea completed self-administered risk behavior questionnaires, comprising 5 domains : demographics, smoking, drinking, drug abuse and sexual behavior. Results : The rate of smoking experience was...
Serum Lipids of School Children and Adolescence in Urban and Rural Area
Dong Han Shin, Hee Sun Lee, Kee Hyoung Lee, Baik-Lin Eun, Chae Seung Lim, Young Chang Tockgo
Clin Exp Pediatr. 2004;47(12):1273-1280.   Published online December 15, 2004
Purposes : A cross-sectional study on serum lipids in school children and adolescents was carried out in two different areas in 2002. We studied to determine of the difference in lipids level of children between urban and rural areas and changes of cholesterol levels compared to those of early- 1990 studies. Methods : A cross-sectional study on serum lipids in school...
Clinical Lecture
Growth Assessment and Diagnosis of Growth Disorders in Childhood
Kee Hyoung Lee
Clin Exp Pediatr. 2003;46(12):1171-1177.   Published online December 15, 2003
Original Article
A Follow-up Survey of Mothers' Antenatal Breast-feeding Plans
Hae Soon Kim, Jeong Wan Seo, Yong Joo Kim, Kee Hyoung Lee, Jae Young Kim, Jae Sung Ko, Sun Hwan Bae, Hye Sook Park
Clin Exp Pediatr. 2003;46(7):635-641.   Published online July 15, 2003
Purpose : To investigate the success rate and factors that influence breast-feeding among women having antenatal breast-feeding plans. Methods : Questionnaires included items on success in breast-feeding, reasons for failure and perinatal factors. It was done by telephone calls to 152 randomly selected women having antenatal breast-feeding plans at 4 months after delivery. The questionnaires were analysed by bivariate χ2-...
Overnight Growth Hormone Secretions and Sleep Patterns in Idiopathic Short Stature Children
Sang Young Seo, Kee Hyoung Lee, Baik Lin Eun, Chang Sung Sohn, Young Chang Tockgo, Chol Shin, Baek-Hyun Kim
Clin Exp Pediatr. 2003;46(4):363-369.   Published online April 15, 2003
Purpose : Pharmacologic provocation test of growth hormone(GH) is a non-physiologic method and has several limitations for diagnosing growth hormone(GH) deficiency. Spontaneous GH release studies could be important in understanding the pathophysiology of children with poor growth but normal responses to GH provocation tests. Also, the relationship between nocturnal GH secretions and sleep patterns in short stature children is poorly...
Case Report
A Case of Melkersson-Rosenthal Syndrome
Dae Hun Pee, Yo Won Na, Ki Young Chang, Woo Keun Seo, Kee Hyoung Lee, Baik-Lin Eun
Clin Exp Pediatr. 2002;45(10):1292-1297.   Published online October 15, 2002
Melkersson-Rosenthal syndrome(MRS) is a rare disorder, having a symptom triad of recurrent facial palsy, orofacial swelling and fissured tongue(lingua plicata). This disorder is usually recurrent or progressive, and monosymptomatic or oligosymptomatic forms have been reported to be more common than classic forms. Generally, MRS occurs in young adults at the end of the second decade of life and incidence of the disease in childhood...
Original Article
The Characteristics of the 2000-2001 Measles Epidemic in the Seoul Metropolitan Area
Dae Hun Pee, So Hoon Byun, Kyung Burm Kim, Young Yoo, Kee Hyoung Lee, Young Kyoo Shin
Clin Exp Pediatr. 2002;45(10):1219-1226.   Published online October 15, 2002
Purpose : To assess the clinical characteristics of the 2000-2001 measles outbreak in the Seoul metropolitan area, Korea, the clinical data of measles inpatients were analyzed. Methods : Three hundred and five children diagnosed with measles by clinical manifestation from July, 2000 to February, 2001, in Seoul, Ilsan and Ansan City were grouped according to their age and investigated for clinical manifestations, vaccination history...
A Survey on the Understanding of Breast-feeding in Pregnant Woman
Jeong Wan Seo, Yong Joo Kim, Kee Hyoung Lee, Jae Young Kim, Jay G Sim, Hae Soon Kim, Jae Sung Ko, Sun Hwan Bae, Hye Sook Park, Beom Soo Park
Clin Exp Pediatr. 2002;45(5):575-587.   Published online May 15, 2002
Purpose : To investigate the understanding of breast-feeding in pregnant woman and the proper way of encouraging breast-feeding. Methods : Each questionnaire included items about demographic characteristics and the understanding of breast-feeding. The questionnaires were filled up by pregnant women visiting obstetric clinics in Seoul and its vicinities, Busan, Choongjoo and Chungjoo from July 2001 to August 2001. One thousand, two...
A Study of Menarche and Dysfunctional Uterine Bleeding in Adolescent School Girls in Ansan City
Yeon Kyeong Jung, Jae Hee Soh, Dae Hun Pee, Young Kyoo Shin, Kee Hyoung Lee, Baik Lin Eun, Sang Hee Park
Clin Exp Pediatr. 2002;45(1):16-23.   Published online January 15, 2002
Purpose : We investigated the menstrual features of adolescent school girls to know the characteristics of menarche and dysfunctional uterine bleeding in adolescents. Methods : In March, 2001, 1,434 primary and middle school girls(10-15 years of age) in Ansan City were investigated for the menacheal age and several aspects of menstruation through questionnaire. Results : Mean age of the total subjects were...
Predisposing Factors of Risk Taking Behaviors in Korean Adolescents
Jae Hee Soh, Yeon Kyeong Jung, Gi Young Jang, Young Kyoo Shin, Kee Hyoung Lee, Baik Lin Eun, Sang Hee Park
Clin Exp Pediatr. 2001;44(12):1364-1373.   Published online December 15, 2001
Purpose : Risk-taking behaviors are defined as patterns of behavior initiated during adolescence which are responsible for the majority of negative health outcomes occurring during the rest of the life. The study was to explore the relationship between the risk-taking behaviors and their predisposing factors among adolescents. Methods : The study used a survey design with an anonymous self-report questionnaire administered to 1,076 students from...
Case Report
A Case of Graves Disease with Kyphosis by Osteoporosis
Yo Won Na, Kee Hyoung Lee, Kee Hwan Yoo, Young Sook Hong, Ju Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 2001;44(8):971-975.   Published online August 15, 2001
Graves disease is the most common clinical feature of hyperthyroidism in childhood. Clinical manifestations include emotional lability, hyperactivity, tremor, excessive sweating, exophthalmos and weight loss. In Graves disease, osteoporosis could occur because of a disturbance of mineral homeostasis which rarely develops from reduced calcium absorption of the gastrointestinal tract and increased urinary calcium excretion related to an increased bone resorption....
A Case of Measles Encephalopathy with Thalamic Lesion on Magnetic Resonance Imaging
Dae Hun Pee, Dae Jin Song, Young Kyoo Shin, Jung Hwa Lee, Kee Hyoung Lee, Baik Lin Eun, Sang Hoon Cha
Clin Exp Pediatr. 2001;44(8):936-941.   Published online August 15, 2001
We experienced a case of measles encephalopathy with thalamic lesion on magnetic resonance imaging(MRI) in a 12 year old boy. Measles symptoms such as fever, erythematous maculopapular rashes on whole body and cough with sputum appeared 4 days before neurologic signs such as agitation and drowsy-to-confused mentality. He showed remarkable motor dysfunction without evidence of sensory loss. MRI showed bilateral...
Medical Lecture Course
Insulin-like Growth Factors and Nutrition
Kee Hyoung Lee
Clin Exp Pediatr. 2001;44(3):235-241.   Published online March 15, 2001
Case Report
Two Cases of Kabuki Make-up Syndrome Including One Case Associated with Xq Isochromosome
Ki Hea Cho, Jung Hwa Lee, Kee Hyoung Lee, Kwang Chul Lee, Ji Tae Choung, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 2000;43(8):1111-1115.   Published online August 15, 2000
Kabuki make-up syndrome(KMS) is characterized by mental and developmental retardation and peculiar facial features including long palpebral fissures with eversion of the lateral portion of lower eyelid and arching of eyebrows, resembling the actors in Japanese Kabuki. In addition, dermatoglyphic and skeletal abnormalities are commonly associated. Although most karyotypes of KMS are shown to be normal, there have been some...
Original Article
Mumps and Rubella-Specific IgG Levels of Term Pregnant W omen and Their Neonates
Young Kyoo Shin, Hae Won Cheon, Kee Hyoung Lee, Ji Tae Choung, Young Chang Tockgo
Clin Exp Pediatr. 1998;41(1):47-52.   Published online January 15, 1998
Purpose : This study was performed to evaluate seropositivities in term pregnant women and their neonates, and the transplacental transfer rate of maternal mumps and rubella- specific IgG from term pregnant women to their neonates. Methods : During Jun. 1, 1994 to Mar. 31. 1995, we collected 44 pairs of sera from pregnant women and their neonates in Anam Hospital of Korea University Medical...
Case Report
A Case of Familial Hypercholesterolemia with Diabetes Mellitus
Yong Kyu Sohn, Kee Young Chang, Kee Hyoung Lee, Young Chang Tockgo
Clin Exp Pediatr. 1997;40(6):862-866.   Published online June 15, 1997
Familial Hypercholesterolemia is the most common hyperlipoproteinemia during the childhood, which occurs from the mutation of genes that regulates low-density lipoproteins(LDL), and is classified into two types, the homozygote presented abnormal genes from both parents and the heterozygote presented an abnormal gene from each parent. Type IIa familial hypercholesterolemia is characterized by, especially, increased level of LDL which is common type and normal level...
A Case of Chronic Pancreatitis with Pancreatic Stones in Childhood
Young Kyoo Shin, Chan Wook Woo, Kee Hyoung Lee, Young Chang Tockgo, Chang Duck Kim
Clin Exp Pediatr. 1995;38(7):1012-1017.   Published online July 15, 1995
Chronic pancreatitis is a rare problem in childhood and sometimes shows pancreatic calcif-ication. The most common symptom is chronic recurrent upper abdominal pain, with waves of crampy pain that increase in severity, with or without associated nausea or vomiting. Although the diagnosis is made or considered infrequently hereditary or other metabolic factors, the cau-se remains largely idiopathic. Endoscopic retrograde cholangiopancreatography(ERCP)...
Original Article
Serum Lipids in Children and Adolescents with Family History of Coronary Artery Diseases
Kee Hyoung Lee, Chang Sung Son, Joo Won Lee, young
Clin Exp Pediatr. 1995;38(4):482-492.   Published online April 15, 1995
Purpose : Atherosclerotic change begins in childhood, elevated blood lipid levels and a family history of premature coronary vascular diseases are important risk factors for coronary artery disease. Identification, follow-up and treatment of children at high risk of cardiovascular diseases are very effective and important for prevention of future coronary artery diseases. The purpose of this study is to determine...
Case Report
A Case of Solid and Papilary Tumor of Pancreas
Kyoung Bum Kim, Hae Won Cheon, Ji Hee Park, Kee Hyoung Lee, Kwang Chul Lee, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(12):1765-1769.   Published online December 15, 1993
We report a cases of solid and papillary neoplasm of the pancreas, which is a rare pancreatic tumor. We described clinical characteristics, sonographic, computed tomographic and pathologic finding. The tumors had a smooth, enhanced capsule and variable internal architecture. The tumor was distributed tail of pancreas without local invasion. The origin of the tumor is probably from a multipotential stem...
Original Article
Plasma Immunoreactive Endothlin-1, Creatine Kinase and CK Isoenzyme and Its Relation to Neonate with-Asphyxia
Kang Woo Lee, Kee Hyoung Lee, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(10):1434-1440.   Published online October 15, 1993
Endotheline-1(ET-1) is a potent vasoconstrictor peptide with 21 amino acid residues. ET-1 is thought to have a key role in vasoconstriction, and cardiac, renal, and endocrine actions of the peptide. Creatine Kinase(CK), also referred to as ATP-creatine-N-phosphotransferase, consists of either the B or M type. CK is found almost exclusively in muscle (MM), myocardium (MB), and brain (BB). It is...
Case Report
A Case of Fetal Atrial Flutter with Hydrops Fetalis
Seong Hang Choi, Kee Hyoung Lee, Chang Sung Sohn, Ju Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(8):1165-1170.   Published online August 15, 1993
Fetal hydrops is often serious and associated with a high perinatal motality rate. Cardiac causes of fetal hydrops include congenital heart diseases and rhythm disturbances. An irregular fetal heart rate may indicate atrial fibrillation and atrial flutter with variable AV conduction. Fetal atrial flutter is characterized by the pressence of flutter waves which are regular sawtooth undulations in the baseline that...
Original Article
A Case of Congenital Myeloblastic Leukemia Associated with Down's Syndrome.
Ho Jin Oh, Kee Hyoung Lee, Chang Sung Son, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(12):1468-1474.   Published online December 31, 1987
A 4 day old male patient was admitted to our hospital due to jaundice, poor feeding and abdominal distention. His clinical features and peripheral blood smear revealed congenital myeloblastic leuke- mia which confirmed by autopsy. Chromosome study showed 47, XY, +21 in Karyotype. We report this case with review of literatures.
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