Clinical and Experimental Pediatrics

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Original Article

Two Siblings of Congenital Hypothyroidsm due to Organification Defect.

Young Kie Park, Kwang Sun Park, Byung Churl Lee

Clin Exp Pediatr. 1989;32(4):582-588. Published online April 30, 1989

Congenital hypothyroidism due to a variety of defects in the biosynthesis of thyroid hormone is detected in 1/30,000-50,000 live births. In the iodide organification defect which is one of defect in the biosynthesis of thyroid hormone, iodide is not organified and may be rapidly discharged from the thyroid by administration of perchlorate. We experienced two siblings who had short stature, goiter, mental retardation, constipation and other...

A Clinical Study of Congenital Hypertrophic Pyloric Stenosis.

Kwang Sun Park, Young Ki Park, Jong Wan Kim, Chang Kyu Oh, Mahn Kyoo Yang

Clin Exp Pediatr. 1989;32(1):27-33. Published online January 31, 1989

We experienced 23 patients with congential hypertrophic pyloric stenosis from Dec. 1978 to Aug. 1987 The age and sex distribution, family and birth history, clinical symptoms with prognosis etc. were reviewed. The results were as follows. 1) Most of the patients (20 cases, 87%) represented symptoms within 6 weeks of age. 2) Male was predominated than female by the ratio of 19:4. 3) The first baby was...

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