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Case Report
Transient asymptomatic white matter lesions following Epstein-Barr virus encephalitis
Yoon Young Jang, Kye Hyang Lee
Clin Exp Pediatr. 2011;54(9):389-393.   Published online September 30, 2011

We present the case of a patient with Epstein-Barr virus (EBV) encephalitis who developed abnormal white matter lesions during the chronic phases of the infection. A 2-year-old-boy was admitted for a 2 day history of decreased activity with ataxic gait. The results of the physical examination were unremarkable except for generalized lethargy and enlarged tonsils with exudates. Brain magnetic resonance...

Original Article
The neuroprotective effect of recombinant human erythropoietin via an antiapoptotic mechanism on hypoxic-ischemic brain injury in neonatal rats
Moon Sun Kim, Yoo Kyung Seo, Hye Jin Park, Kye Hyang Lee, Kyung Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Woo Taek Kim
Clin Exp Pediatr. 2010;53(10):898-908.   Published online October 31, 2010
Purpose

The neuroprotective effects of erythropoietin (EPO) have been recently shown in many animal models of brain injury, including hypoxic-ischemic (HI) encephalopathy, trauma, and excitotoxicity; however, limited data are available for such effects during the neonatal periods. Therefore, we investigated whether recombinant human EPO (rHuEPO) can protect against perinatal HI brain injury via an antiapoptotic mechanism.

Methods

The left carotid artery was ligated...

Case Report
Transient splenial lesion of the corpus callosum in a case of benign convulsion associated with rotaviral gastroenteritis
Yoon Young Jang, Kye Hyang Lee
Clin Exp Pediatr. 2010;53(9):859-862.   Published online September 13, 2010

Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized...

Original Article
Taurine exerts neuroprotective effects via anti-apoptosis in hypoxic-ischemic brain injury in neonatal rats
Ji Eun Jeong, Tae Yeol Kim, Hye Jin Park, Kye Hyang Lee, Kyung Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Eok Su Seo, Woo Taek Kim
Clin Exp Pediatr. 2009;52(12):1337-1347.   Published online December 15, 2009
Purpose : Taurine (2-aminoethanesulfonic acid) is a simple sulfur-containing amino acid. It is abundantly present in tissues such as brain, retina, heart, and skeletal muscles. Current studies have demonstrated the neuroprotective effects of taurine, but limited data are available for such effects during neonatal period. The aim of this study was to determine whether taurine could reduce hypoxic-ischemic (HI) cerebral...
Assessment of parental understanding of epilepsy and effects of educational programs in an epilepsy camp
Sung Min Cho, Soon Hak Kwon, Doo Kwun Kim, Jun Sik Kim, Han Koo Moon, Hye-Eun Se, Kye Hyang Lee, Eun Ju Lee, Jun Hwa Lee, Nho Eun Kim
Clin Exp Pediatr. 2009;52(5):549-556.   Published online May 15, 2009
Purpose : To assess parental knowledge and understanding of epilepsy including social stigma and evaluate the effects of educational programs on parents in an epilepsy camp. Methods : We conducted an epilepsy camp on August 23-24, 2008, at Gyeongsan. Twenty families with an epileptic child each participated in the camp. We performed a survey before and after the camp to...
Case Report
A case of lethal kwashiorkor caused by feeding only with cereal grain
Hyun Ju Lee, Kyung Hye Km, Hye Jin Park, Kye Hyang Lee, Gyeong Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Woo Taek Kim
Clin Exp Pediatr. 2008;51(3):329-334.   Published online March 15, 2008
Kwashiorkor is a syndrome of severe protein malnutrition, which manifests itself in hypoalbuminemia, diarrhea, dermatitis, and edema. It can be life-threatening due to associated immune deficiency and an increased susceptibility to infections. Kwashiorkor should be treated early with nutritional support and the control of infection. Dilated cardiomyopathy may develop during the treatment and in such cases a poor prognosis is...
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