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Case Report
A Case of 2-Methylbutyryl-CoA Dehydrogenase Deficiency
Moon Souk Lee, Ho Jin Park, In Kyu Lee, Kyuchul Choeh, Hye-Ran Yoon
Clin Exp Pediatr. 2004;47(1):100-105.   Published online January 15, 2004
We report a one-day-old Korean boy with 2-Methylbutyryl-CoA dehydrogenase(2-MBCDase) deficiency detected by urine organic acid and acylglycine analysis, plasma acylcarnitine analysis and confirmed by enzyme assay and Western blot. The patient was born at 35 weeks and three days with oligohydroamnios and premature rupture of membrane for 31 hours, as a second child of healthy non-consanguineous parents. There was no...
Original Article
Comparison of Effectiveness between Two Different Protocols of Treatment of IV γ-globulin in Idiopathic Thrombocytopenic Purpura
Jae Ho Jang, Moonsouk Lee, Mira Park, Kyuchul Choeh
Clin Exp Pediatr. 2003;46(4):358-362.   Published online April 15, 2003
Purpose : Several methods of IV γ-globulin(IVG) infusion are effective in the treatment of autoimmune disease, including idiopathic thrombocytopenic purpura(ITP). But it is not known which method is more effective in the treatment of ITP. The effectiveness of these two methods of IVG infusion was studied in terms of platelet recovery rate, side effects and recurrence rate. Methods : Forty seven...
Case Report
MR Imaging of Disseminated Tuberculosis of the Brain in a Patient with Miliary Tuberculosis : Initial Findings and Changes Six Months after Antituberculous Therapy
Jae Ho Jang, Jae Woo Lim, Soon Lee Jung, Kyuchul Choeh, Taeil Han
Clin Exp Pediatr. 2002;45(12):1596-1600.   Published online December 15, 2002
A 23-month-old girl visited with chronic cough and her chest radiograph showed miliary tuberculosis. There was no neurological abnormality. But CSF findings showed WBC 22/mm3(lymphocyte 20%, neutrophil 80%) and positive result of polymease chain reaction(PCR) for M. tuberculosis. MR imaging showed multiple ring enhanced nodules and ovoid nonenhancing bright signal lesion on the cerebrum, cerebellar parenchyme, and left basal ganglia....
Idiopathic Thrombocytopenic Purpura
Kyuchul Choeh
Clin Exp Pediatr. 2001;44(2):115-118.   Published online February 15, 2001
Original Article
The Correlation Between the TSH Level in Neonatal Screening Test and the Prognosis of Congenital Hypothyroidism
Hong Sun Park, Kye Shik Shim, Kyuchul Choeh
Clin Exp Pediatr. 2001;44(1):25-31.   Published online January 15, 2001
Purpose : It is important to diagnose and treat newborn patients with congenital hypothyroidism as soon as possible because of neurodevelopmental outcome. If we can detect more severe forms of congenital hypothyroidism with neonatal screening test, the results of treatment will improve. Methods : Sixty-four term infants whose TSH levels in neonatal screening test had been higher than 20μIU were recalled....
The Effect of Massage on Premature Infants
Hee Sook Son, Jae Woo Lim, Kyuchul Choeh, Chang Soo Ra, Hark Hee Kim
Clin Exp Pediatr. 2000;43(8):1046-1051.   Published online August 15, 2000
Purpose : To determine the effects of massage therapy on growth, development, hormones, immune function, hepatic function, hematopoietic function and sleep pattern of preterm infants. Methods : Thirty-one preterm infants of less than 35 weeks gestational age, who were admitted to Eulji Medical College Hospital Neonatal Intensive Care Unit between August 1998 and May 1999, and were in the state without mechanical ventilation or...
Case Report
A Case of Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
Jae Woo Lim, Jong Su Shin, Kyuchul Choeh, Chang Su Na, Tae Il Han
Clin Exp Pediatr. 2000;43(2):278-282.   Published online February 15, 2000
Megacystis Microcolon Intestinal Hypoperistalsis(MMIH) Syndrome is a rare cause of functional neonatal bowel obstruction, characterized by hypoperistalsis, narrow distal ileum and colon, and bladder distension. We report a case of MMIH syndrome and review the literature. The patient was born after 34 weeks of gestation with marked abdominal distension. Her birth weight was 2,830g with 276ml of urine drained by...
Original Article
The Annual and Seasonal Changes in the Prevalence of Rotaviral Infection from; 1993 to 1998
Young Joo Son, Hong Sun Park, Soon Lee Jung, Mira Park, Kyuchul Choeh
Clin Exp Pediatr. 2000;43(1):49-54.   Published online January 15, 2000
Purpose : Rotavirus infection is a leading cause of severe gastroenteritis among infants and young children worldwide. In temperate regions, institutional outbreaks of the disease occur mainly in cold dry weather, whereas in tropical settings its seasonal course is less well defined. We studied the annual changes in the seasonal prevalence of rotavirus infection for 5 years. Methods : The study was conducted on...
Case Report
A Case of Congenital Lobar Emphysema on Right Lower Lobe
Jong Su Shin, Seok Hee Oh, Eun Ju Kim, Kyuchul Choeh, Jai Won Lee
Clin Exp Pediatr. 1998;41(8):1157-1160.   Published online August 15, 1998
Original Article
On the Significance of Blood Sampling Time in Neonatal Neurologic Prognosis Using Creatine Kinase BB
Heung Taek Kim, Mi Kyung Son, Eun Ju Kim, Kyuchul Choeh
Clin Exp Pediatr. 1998;41(5):669-676.   Published online May 15, 1998
Purpose : To investigate the cut-off value of creatine kinase(CK) BB according to blood sampling time in predicting neonatal prognosis, we studied the time-related releasing pattern of CK isoenzymes after birth asphyxia. Methods : CK was measured within 1 hour and at 6-10 hours after birth from 45 newborn infants who were suspected to be perinatal asphyxia or fetal distress. The...
Case Report
A Case of DiGeorge Syndrome
Young Joo Son, Yu Sik Jeon, Soon Lee Jung, Kyuchul Choeh
Clin Exp Pediatr. 1998;41(3):390-395.   Published online March 15, 1998
We experienced a case of DiGeorge syndrome in a 25-day-old male infant presented with micrognathia, short neck, fish-shaped mouth and intractable seizures with a loading dose of phenobarbital & dilantin. The serum calcium level was 3.7mg/dl, ionized calcium level was 0.62mmol/L, and parathyroid hormone carboxy-terminal level was 0.01ng/ml. We treated with it calcium gluconate infusion, low phosphorous formula milk feeding, and...
A Case of Slowly Progressing Aneurysm of Left Ventricle and Thoracic Aorta Due to Automobile Blunt Trauma
Eun Ju Kim, Yu Sik Jeon,, Kyuchul Choeh, Jae Kyun Shin, Jeong Tae Ahn, Dong Man Seo
Clin Exp Pediatr. 1998;41(2):259-263.   Published online February 15, 1998
A five-year-old boy received a blunt trauma on chest by a kindergarten bus on Feb. 29, 1996. Pulmonary hemorrhage and pericardiac effusion were developed, followed by multi-organ failure threatening his life. All symptoms were improving when pansystolic harsh murmur(Ⅲ/Ⅵ) originating from a tiny ventricular rupture with a blood leak to the pericardial space was auscultated on the 12th day after the...
A Case of Trisomy 9 Syndrome
yu Sik Jeon, Heung Tak Kim, Soon Hee Jeong, Kyuchul Choeh
Clin Exp Pediatr. 1998;41(2):255-258.   Published online February 15, 1998
Since Feingold and his collegues first describes the trisomy 9 syndrome in 1973, approximately 30 patients with trisomy of the chromsome 9 have been described. Trisomy 9 has been reported as either partial or complete. Complete trisomy is rare and incompatible with a a long life. Before this report, this syndrome has not been reported in Korea. A neonate was diagniosed...
Original Article
Clinical Trial of 2g/kg/day of Intravenous Immunoglobulin Single Dose as Compared with 400mg/kg/day of Intravenous Immunoglobulin for 5days in Kawasaki Disease
Seok Hee Oh, Heung Tag Kim, Hae Jin Chech, Kyuchul Choeh
Clin Exp Pediatr. 1997;40(11):1582-1587.   Published online November 15, 1997
Purpose : Since the effect of intravenous immunoglobulin (IVIG) therapy in Kawasaki disease was reported in 1984, the combined therapy of IVIG & oral aspirin has been popular. In early period, the protocol of 400mg/kg/day for 3-5 days of IVIG had been used, but rescently, the protocol of 2g/kg/day single dose has been preferred. So authers performed a clinical study to compare th efficacies...
Case Report
A Case of Pyloric Atresia Associated with Epidermolysis Bullosa
Mi Kyung Son, Te Kyung Lee, He Jin Choeh, Kyuchul Choeh
Clin Exp Pediatr. 1996;39(7):1015-1019.   Published online July 15, 1996
We have experienced a case of congenital pyloric atresia associated with epidermolysis bullosa in a premature newborn who was born at the gestation period of 33+3 week. She showed a few blisters on left ankle at birth and the easy formation of blisters involving the area of trauma or friction with depigmentation after healing. The histologic finding of the lesion showed junctional epidermolysis bullosa. Abdominal...
Original Article
Significance of Creatine Kinase Isoenzymes for Neurologic Outcome in Perinatal Asphyxia
Mi Kyung Son, Eun Sik Kang, Sun Hi Jung, Kyuchul Choeh
Clin Exp Pediatr. 1996;39(7):924-933.   Published online July 15, 1996
Purpose : To investigate the usefulness of the serum Creatine kinase(CK), especially brain typical creatine kinase(CK-BB) as an indicator of brain damage extent, mortality and long term nurologic sequelae, the study was done. Methods : CK and CK isoenzyme activites were measured at 6-10 hours after birth in 160 asphyxiated newborn infants who admitted in Eulji General Hospital from August 1990 to July 1994. Infants...
Medical Lecture Course
Molecular Biology in Prenatal Diagnosis for Inborn Error of Metabolism
Kyuchul Choeh
Clin Exp Pediatr. 1996;39(5):603-611.   Published online May 15, 1996
Case Report
A Case of Septo-Optic Dysplasia
Tae Kyong Lee, Eui Ja Kang, Eun Sik Kang, Hae Jin Choeh, Kyuchul Choeh
Clin Exp Pediatr. 1996;39(2):287-290.   Published online February 15, 1996
Septo-optic dysplasia, as first described by de Morsier, is a rare developmental anomaly involving optic nerve hypolasia, midline anomalies of the brain and variable hypothalamicpituitary dysfunction. We experienced a case of septo-optic dysplasia in 56-day old male infant who presented with prolonged jaundice. A magnetic resonance imaging of the brain showed absence of the septum pellucidum and the ophthalmoscopic examination...
Original Article
The Correlation between the Duration of Breast Feeding and Iron Deficiency Anemia(IDA)
Yee Ja Kang, Ha Sin Park, Hae Jin Choeh, Kyuchul Choeh
Clin Exp Pediatr. 1995;38(11):1453-1459.   Published online November 15, 1995
Purpose : Iron deficiency anemia(IDA) is the most common nutritional deficiency. in young infants. This study was designed to determine a correlation between the duration of breast feeding and the severity of IDA, and to determine the recommending start point of iron fortified diet. Methods : The correlation between duration of breast feeding, and severity of iron deficiency. and IDA was...
Prediction of Neurologic Outcome of Perinatal Asphyxia by Use of CK-BB Isoenzyme Measurements
Eun Sik Kang, Jung Hea Park, Hea Jin Choeh, Chong Sung Chung, Kyuchul Choeh
Clin Exp Pediatr. 1994;37(1):19-25.   Published online January 15, 1994
Creatine kinase (CK) isoenzyme are considered as a specific tissue injury marker. Brain tyupe isoenzyme of CK (CK-BB) was measured in 44 healthy and 33 asphyxiated preterm and fullterm infants. Samples were drawn from peripheral blood at six to ten hours after birth. There were no difference of CK-BB and CK-BB% between preterm and fullterm infants. CK-BB and CK-BB% were well...
Indirect Measurement of Blood Pressure in Neonates Using an Automatic Noninvasive Oscillometric Monitor
Jung Hea Park, Hea Jin Choeh, Eun Sik Kang, Chong Sung Chung, Kyuchul Choeh
Clin Exp Pediatr. 1993;36(9):1211-1218.   Published online September 15, 1993
The measurement of blood pressure in neonates is an important diagnostic procedure. But the measurement of blood pressure has not been performed routinely because of difficulty in measuring blood pressure and varable normal range according to measuring apparatus. Recently some accurate and convenient apparatus of measuring blood pressure have been introduced in neonatal care, so the reference values...
Case Report
Rhinocerebral Mucormycosis : A case Report
Kyuchul Choeh, Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Won Sil Huh, Hyun Sook Chi
Clin Exp Pediatr. 1992;35(9):1267-1271.   Published online September 15, 1992
We experienced a case of rhinocerebral form of mucormycosis in a 9-year-old male suffered from acute lymphocytic leukemia(FAB L2). On 15th day of induction chemotherapy(Hospital day 23) pain, tenderness and swelling on left maxillary sinus. He expired on Hospital day 47.
Original Article
Change of NK Cell and LAK Cell Activity of Cancer Patients in Postchemotherapy Period.
Chong Sung Chung, Kyuchul Choeh, Yong Mook Choi
Clin Exp Pediatr. 1989;32(7):933-942.   Published online July 31, 1989
This study was undertaken to evaluate the Natueral-Killer (NK) cell and Lymphokine-Activated-Killer (LAK) cell activity of cancer patients for the prupose of understanding of spontaneous cell-mediated cytotoxicity (SCMC) in cancer patients and understanding of interrelationship between NK cell and LAK cell. Total 9 cases of malignant tumor (7 cases: Acute leukemia, 2 cases: malignant lymphoma) below 15 years of age, who were on remission...
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