Purpose : Iron deficiency anemia (IDA) is one of the most common nutritional deficiencies in children on a weaning diet. We investigated weaning practices in infants and children, as well as their mothers' knowledge about weaning. Methods : We investigated 129 children with IDA and 166 without IDA (aged 6-36 months) who had visited 10 university hospitals between March 2006... |
Purpose : Despite the seriousness of bacterial meningitis in children, there is little information on the incidence, causative organisms, mortality rate and age distribution. We studied the frequency by age group and causal pathogens, and clinical characteristics in children with bacterial meningitis in the private sector in Korea. Methods : The medical records containing the data on bacterial meningitis patients... |
Purpose : Penicillin- and multidrug-resistant S. pneumoniae poses a serious threat to clinicians because the rate of resistance of S. pneumoniae to penicillin in Korea has surged up to the world's highest level. This study was performed to assess the carriage rate, serogroups and antimicrobial susceptibility of S. pneumoniae isolated from oropharynx in children. Methods : From March to July 1998,... |
Purpose : The incidence of obese patients has increased recently in Korea. Obesity is associated with hypertension, hyperlipidemia, insulin resistance, and fatty liver. Since recent investigators have revealed that not only fat accumulation but also fibrosis and nonspecific hepatitis can be found in the livers of obese children, fatty liver is currently considered as an important complication. The purpose of... |
Purpose : Receptors for the Fc of IgG(FcγR) and a β2 integrin molecule, CD11c/CD18 are important in clearance of microbes by granulocytes. We performed an in vitro study on the effect of recombinant human granulocyte colony-stimulating factor(rhG-CSF), or granulocyte-macrophage colony-stimulating factor(rhGM-CSF) on the expression of FcγR II, FcγR III, CD11c and CD18 and respiratory burst function of granulocytes. Methods : Peripheral... |
Purpose : Thawed stem cells should be infused as early as possible because delay of infusion leads to decrease of cell viability and formation of DNA clumping. The procedure of 10% Dimethyl sulfoxide(DMSO) removal and a long distance from the thawing location to the patient are the main causes of delay of infusion that results in the loss of cell... |
Purpose : Aggressive chemotherapy and bone marrow transplantation have a large demand for platelet concentrate and packed RBC transfusion. Febrile nonhemolytic transfusion reactions are an immunologically mediated reaction involving plasma in the recipient and the white blood cells in the donor. This study was performed to understand the role of cytokines and factors associated with febrile nonhemolytic transfusion reaction to... |
Purpose : The neonate is susceptible to severe and overwhelming bacterial infections. One of the most important deficiency in the neonatal host defense system seems to be quantitative and qualitative deficiency of the myeloid and the phagocytic system. Granulocyte colony-stimulating factor(G-CSF) has been shown to induce neutrophilia and enhance mature effector neutrophil function. We examined serum levels of G-CSF in... |
Purpose : Homatopoietic stem cells, which have the ability to undergo self-renewal as well as to develop into multipotential differentiations, have been consistantly demonsteraten in human umbilical cord blood. Recently, there have been a few studies using the umbilical cord blood as a source of stem cell transplantation. However it remains unclear whether umbilical cord blood in safe with regards to... |
Stem cell transplantation is used for the patients lacking the capability of production of hem-atopoitic cells. Recently, there have been a few studies using the umbilical cord blood as a sou-rce of stem cells, however it remains unclear whether umhhilical cord blood contains sufficient amount to reconstitute the patient. Our study was designed to know that umbilical cord blood is proper... |
Idiopathic hypercalciuria is defined as increased urinary excretion of calcium in normocalcemia without primary cause. It is associated with urinary symptoms, such as hematuria but it occurs without any symptoms too. If left untreated, it may cause kidney stone, dimineralization of bone, or other problem. The incidence of idiopathic hypercalciuria was 3.9% in asymptomatic group compared to 5% in unselected populations in this study.... |
Transient Neonatal D.M. is rare disease which is characterized by letharginess, dehydration and weight loss with severe hyperglycemia. It occurs frequently which small for data infant and recovers spontaneously if appropriate insulin treatment was taken. We had expirienced a case of Transient Neonatal D.M. in 15 days old female infant. The review of the literature was made briefly. |
Neonatal Hyperbilirubinemia due to ABO Incompatibility was contributed to Kemicterus in our country. We studied the difference between ABO compatible group and incompatible group, such as, day of appearance of Hyperbilirubinemia, tendency of bilirubin concentration change, reticulocyte, hemoglo- bin, and duration of Hyperbilirubinemia. As a result, clinical symptoms were more severe in incom- patible group rather than compatible group. And so, we stress to early diagnosis... |
Isoimmune thrombocytopenic purpura is an uncommon cause of purpura in the newborn infant, caused by fetal-maternal platelet incompatibility. The maternal isoantibodies against fetal platelet antigens, which are lacked in mother’s platelets, cross placenta and cause destructions of baby’s platelet. A bady bom with IITP was diagnosed in the first day of life and treated successfully with platelet concentrate of mother’s blood. |