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Case Report
Hepatic glycogenosis in type 1 diabetes mellitus mimicking Mauriac syndrome
In Ah Jung, Won Kyoung Cho, Yeon Jin Jeon, Shin Hee Kim, Kyoung Soon Cho, So Hyun Park, Min Ho Jung, Byung-Kyu Suh
Clin Exp Pediatr. 2015;58(6):234-237.   Published online June 22, 2015

Hepatic glycogenosis in type 1 diabetes mellitus (DM) can be caused by poor glycemic control due to insulin deficiency, excessive insulin treatment for diabetic ketoacidosis, or excessive glucose administration to control hypoglycemia. Mauriac syndrome, which is characterized by hepatomegaly due to hepatic glycogenosis, growth retardation, delayed puberty, and Cushingoid features, is a rare diabetic complication. We report a case of...

Original Article
Association between serum alanine aminotransferase level and obesity indices in Korean adolescents
Moon Bae Ahn, Woo Ri Bae, Kyung Do Han, Won Kyoung Cho, Kyoung Soon Cho, So Hyun Park, Min Ho Jung, Byung Kyu Suh
Clin Exp Pediatr. 2015;58(5):165-171.   Published online May 22, 2015
Purpose

To analyze the correlation between serum alanine aminotransferase (ALT) and obesity indices including body mass index (BMI), body fat percentage (BFP), total fat mass (FM), truncal fat mass (TFM), waist circumference (WC), and waist-to-height ratio (WHtR) in Korean adolescents.

Methods

This was a cross-sectional study based on data derived from the 2010-2011 Korean National Health and Nutrition Examination Surveys (KNHANES). Subjects were...

Risk factors for short term thyroid dysfunction after hematopoietic stem cell transplantation in children
You Jin Jung, Yeon Jin Jeon, Won Kyoung Cho, Jae Wook Lee, Nack-Gyun Chung, Min Ho Jung, Bin Cho, Byung-Kyu Suh
Clin Exp Pediatr. 2013;56(7):298-303.   Published online July 19, 2013
Purpose

The purpose of this study was to evaluate short-term thyroid dysfunction and related risk factors in pediatric patients who underwent hematopoietic stem cell transplantation (HSCT) during childhood.

Methods

We studied 166 patients (100 boys and 66 girls) who underwent HSCT at the Catholic HSCT Center from January 2004 through December 2009. The mean age at HSCT was 10.0±4.8 years. Thyroid function of...

Evaluation of changes in random blood glucose and body mass index during and after completion of chemotherapy in children with acute lymphoblastic leukemia
Kyong-Won Bang, Soo Young Seo, Jae Wook Lee, Pil-Sang Jang, Min Ho Jung, Nack-Gyun Chung, Bin Cho, Dae-Chul Jeong, Byung Kyu Suh, Hack-Ki Kim
Clin Exp Pediatr. 2012;55(4):121-127.   Published online April 30, 2012
Purpose

Improved survival of patients with childhood acute lymphoblastic leukemia (ALL) has drawn attention to the potential for late consequences of previous treatments among survivors, including metabolic syndrome. In this study, we evaluated changes in 3 parameters, namely, random blood glucose, body mass index (BMI), and Z score for BMI (Z-BMI), in children with ALL during chemotherapy and after completion of...

A case of meningoencephalitis caused by Listeria monocytogenes in a healthy child
Ji Eun Lee, Won Kyoung Cho, Chan Hee Nam, Min Ho Jung, Jin Han Kang, Byung Kyu Suh
Clin Exp Pediatr. 2010;53(5):653-656.   Published online May 31, 2010

Listeria monocytogenes is a facultative anaerobic, gram-positive bacillus that is isolated from the soil, vegetables, and wild or domestic animals. Listeria occurs predominantly in the elderly, immunocompromised patients, pregnant women and newborns. Infections by this microorganism are rare in healthy infants and children. L. monocytogenes may cause meningitis, meningoencephalitis, brain abscess, pyogenic arthritis, osteomyelitis, and liver abscesses in children. The...

Analysis of gonadotropin-releasing hormone (GnRH) test results in girls with precocious puberty
Jung Yun Choi, Hyun-Ju Kang, Won Kyoung Cho, Kyoung Soon Kim, So Hyun Park, Seung Hoon Hahn, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2009;52(12):1377-1382.   Published online December 15, 2009
Purpose : The gonadotropin-releasing hormone (GnRH) test results of girls with precocious puberty were analyzed to determine whether this test can efficiently and clearly differentiate between central precocious puberty (CPP) and other disorders. Methods : Clinical and laboratory data of 54 girls with precocious pubertal signs were reviewed. Intravenous GnRH test was performed with blood samples obtained at 0, 30,...
Serum leptin, adiponectin and resistin levels in obese children and their correlations with insulin resistance
Min Young Park, Sun A Ahn, Won Kyoung Cho, Kyoung Soon Cho, So Hyun Park, Seung Hoon Hahn, Min Ho Jung, Byung-Kyu Suh
Clin Exp Pediatr. 2009;52(7):766-771.   Published online July 15, 2009
Purpose : The objective of this study was to compare the levels of adipocytokines in obesity group with those in control group and examine their correlation with insulin resistance. Methods : We enrolled 36 obese children (male:female [M:F]=17:19; age, 9.3±1.9 yrs) with ≥95th percentile body mass indexes (BMIs) (obesity group) and 35 healthy children (M:F=16:19; age, 9.1±2.1 yrs) with 25th-75th percentile...
Serum ghrelin and leptin concentrations in children with cancer : comparisons with normal children
So Hyun Park, Min Ho Jung, Nac Gyun Chung, Byung-Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2007;50(9):905-911.   Published online September 15, 2007
Purpose : Ghrelin, being secreted from the stomach, stimulates growth hormone secretion and controls energy homeostasis by increasing appetite. Leptin, being secreted from the adipocytes, controls weight and energy homeostasis by decreasing appetite. Leptin concentration is reported to increase after childhood cancer therapy. This study was aimed to compare ghrelin and leptin concentrations in normal children and children who received...
Case Report
A case of adrenocortical adenoma following long-term treatment in a patient with congenital adrenal hyperplasia
Seung Rim Lho, So Hyun Park, Min Ho Jung, Byung Churl Lee
Clin Exp Pediatr. 2007;50(3):302-305.   Published online March 15, 2007
As a result of the widespread use and enhanced quality of high-resolution radiological techniques, a recent report has revealed a relatively high prevalence of small adrenal tumors in patients with untreated congenital adrenal hyperplasia due to 21-hydroxylase deficiency. However, there are scarcely any pediatric cases of adrenocortical tumor following long-term treatment in patients suffering with congenital adrenal hyperplasia. We report...
Original Article
Tumor Necrosis Factor and Lymphotoxin-α Gene Polymorphism in Korean Children with Type 1 Diabetes
Jin Soon Suh, So Young Park, Min Ho Jung, Byung Kyu Suh, Tae Gyu Kim, Byung Churl Lee
Clin Exp Pediatr. 2005;48(8):871-876.   Published online August 15, 2005
Purpose : Recently, it was reported that tumor necrosis factor(TNF) and lymphotoxin-α(LT-α) gene regions might be a susceptible loci to type 1 diabetes in Japanese. The purpose of this study was to investigate the association of TNF and LT-α gene polymorphisms with disease susceptibility in Korean children with type 1 diabetes. Methods : Forty-nine Korean children with type 1 diabetes(29...
Case Report
A Case of Cystinosis
Min Ho Jung, Seung On Keun, Soon Ju Lee, Byung Churl Lee
Clin Exp Pediatr. 2003;46(6):615-619.   Published online June 15, 2003
Cystinosis, an autosomal recessively inherited lysosomal storage disease, results from impaired transport of the amino acid cystine out of cellular lysosomes. The consequent accumulation and crystallization of cystine destroys tissues, causing growth retardation, Fanconi syndrome, renal failure, eye problems, and endocrinopathies. The gene for cystinosis, CTNS, was mapped to chromosome 17p13. The diagnosis of cystinosis was made by measuring the...
Original Article
Graves` Disease in Prepubertal Children Compared with Pubertal Children
Hyun Mi Kim, Ju Yun Yoon, Min Ho Jung, Byung Kyu Suh, Byung Churl Lee
Clin Exp Pediatr. 2003;46(1):76-82.   Published online January 15, 2003
Purpose : The aim of this study was to determine whether differences exist in the presentation, clinical course, and outcome of Graves' disease between prepubertal children and adolescents. Methods : A retrospective chart review of 14 prepubertal(PREPUB, 7.2?.9 yr) and 38 pubertal (PUB, 12.4?.5 yr) children with Graves' disease between January 1989 and November 1995 at St. Mary's Hospital and Kangnam...
Changes of Bone Metabolism Markers and Bone Mineral Density with Improvement of Thyroid Function in Children and Adolescents with Hyperthyroidism
Min Ho Jung, Choong Ho Shin, Sei Won Yang, Byung Churl Lee
Clin Exp Pediatr. 2002;45(6):743-753.   Published online June 15, 2002
Purpose : Dynamics of bone mineral density(BMD) and bone metabolism in children and adolescents with hyperthyroidism have not been thoroughly investigated. The aim of this study was to study how the improvement of thyroid function with antithyroid treatment influenced bone metabolism and BMD in children and adolescents with hyperthyroidism. Methods : Serum levels of osteocalcin(OC), bone-specific alkaline phosphatase(b-ALP), and carboxyterminal telopeptide...
Factors Related to the Development of Microalbuminuria in Children and Adolescents with Type 1 Diabetes Mellitus
Min Ho Jung, Pei Tai Wan, Choong Ho Shin, Sei Won Yang
Clin Exp Pediatr. 2001;44(5):577-586.   Published online May 15, 2001
Purpose : We observed the prevalence rate of microalbuminuria(MA) and its relationship with the various clinical factors in children and adolescents with type 1 diabetes mellitus(DM). Methods : Seventy two children and adolescents(26 males and 46 females, 17.1±3.0 years) were included. MA was defined as 24 hour urine microalbumin >30mg/day(20μg/min). Subjects were classified into three groups(normoalbuminuria, transient MA, or persistent MA)....
Factors Affecting the Presence of Menarche and Final Adult Height in Adult Female Patients with Congenital Adrenal Hyperplasia of 21-Hydroxylase Deficiency
Seong Yong Lee, Chae Kyoung Song, Min Ho Jung, Jin Soon Hwang, Sei Won Yang
Clin Exp Pediatr. 2001;44(1):75-82.   Published online January 15, 2001
Purpose : Amenorrhea and short stature are serious complications in patients with congenital adrenal hyperplasia of 21-hydroxylase deficiency(CAH). We analysed several factors influencing the presence of menarche and final adult height in these patients. Methods : We retrospectively reviewed medical records of 24 female patients with CAH. We analysed possible factors affecting the menarche and final adult height, such as clinical...
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