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Original Article
Valproate-associated weight gain and potential predictors in children with epilepsy
Gook Chan Jang, Eun Young Kim, Young Il Rho, Kyung Rye Moon, Sang Kee Park
Clin Exp Pediatr. 2007;50(5):484-488.   Published online May 15, 2007
Purpose : The purpose of this study was to determine the incidence and potential predictors of weight gain in older children and teens treated with valproate (VPA) for epilepsy. Methods : Sixty-five subjects aged 8 to 17 years of age, who began VPA treatment between January 1, 2001, and December 31, 2004, and who had documented weight and height measurements...
Effect of maternal thyroxine treatment on the offspring's brain development with fetal alcohol effects in the rats
Jin Fu, Yoon Young Chung, Sang Kee Park
Clin Exp Pediatr. 2006;49(6):677-685.   Published online June 15, 2006
Purpose : This study aimed to investigate whether exogenous thyroxine(T4) treatment to alcohol-fed dams would ameliorate the detrimental effects of alcohol on the postnatal development of neuropeptide-Y(NPY)-containing neurons of the cerebral cortex and hippocampus of the offspring. Methods : Time-pregnant rats were divided into three groups. An alcohol-fed group A received 35 calories of liquid alcohol diet daily from gestation day...
Pain reduction at venipuncture in newborn infants : oral glucose solution, EMLA cream and pacifiers
Sang Kee Park, Eun Young Kim
Clin Exp Pediatr. 2006;49(4):388-393.   Published online April 15, 2006
Purpose : We compared the pain reducing effect of orally administered glucose solution with EMLA cream and pacifiers during venipuncture in newborn infants. Methods : Fifty newborn infants(30 prematures) were enrolled in this study. We performed these four pain-reducing methods to all infants in serial order. Group A(control) did not receive any treatment; to group B, EMLA cream was applied on...
Perinatal Factors Affecting Thyroid Stimulating Hormone(TSH) and Thyroid Hormone Levels in Cord Blood
Eun Young Kim, Sang Kee Park, Chang Hun Song, Sung-Chul Lim
Clin Exp Pediatr. 2005;48(2):143-147.   Published online February 15, 2005
Purpose : The aim of the this study was to evaluate the effect of various perinatal conditions on TSH and thyroid hormone levels in cord blood. Methods : Cord blood samples were collected from 130 neonates immediately after birth. TSH, T3, and free T4 levels were measured by the radioimmunoassay(RIA) method. The effects of gestational age, sex, birth weight, delivery method,...
Prevalence of Orthostatic Dysregulation in Elementary School Students and Frequency of Individual Symptoms
Eun Seok Yang, Eun-Young Kim, Kyoung-Rye Moon, Sang Kee Park, Young Bong Park, Young Il Rho
Clin Exp Pediatr. 2005;48(2):138-142.   Published online February 15, 2005
Purpose : The purpose of the present study was to access the prevalence of orthostatic dysregulation(OD) and the frequency of each category for major and minor criteria among elementary school students using the OD questionnaire. Methods : We carried out inquiry by questionnaire as to the frequency of OD among two elementary schools with 725 students, 10 to 12 years of...
Utilization Patterns of Medical Care of Elementary School Children after the Implementation of Medical Reform : Comparison with a Previous Study in 1998
Eun Seok Yang, Mi Jin Kim, Eun Young Kim, Young Il Rho, Sang Kee Park, Yeong Bong Park, Kyung Rye Moon
Clin Exp Pediatr. 2004;47(9):933-939.   Published online September 15, 2004
Objective : The purpose of this study was to assess the patterns of medical care utilization and factors which determine medical care utilization of elementary school children after the implementation of medical reform. Methods : We performed the questionnaires on 1,031 children from two elementary schools in Gwangju city from June 1 to 30 June, 2001. These data were compared with...
The Relationship between the Perception of Height and Self-Esteem in Children
Mi Jin Kim, Young Il Rho, Eun Seok Yang, Kyung Rye Moon, Sang Kee Park, Yeong Bong Park, Eun Young Kim
Clin Exp Pediatr. 2004;47(3):258-263.   Published online March 15, 2004
Purpose : The aim of this study was to evaluate the behavioral and affective characteristics of children who thought they were short. Methods : Fifteen hundred and twenty-two students of four elementary and middle schools in Gwangju City completed a battery of questionnaires asking about stature-related stress, self-esteem, and personality characteristics. The children were divided into three groups and compared according...
Case Report
A Case of Perinatal Varicella Infection
Jeong A Rho, Young Il Rho, Eun Young Kim, Sang Kee Park
Clin Exp Pediatr. 2003;46(10):1047-1050.   Published online October 15, 2003
Maternal varicella resulting in viremia may transmit the virus to the fetus by either transplacental spread, or by ascending infection from lesion in the birth canal. The characteristic symptoms consist of skin lesions in dermatomal distribution, eye diseases, neurological defects, and limb hypoplasia. Varicella of the newborn is a life-threatening illness that may occur when a newborn is delivered either...
A Case of Craniofrontonasal Dysplasia Diagnosed at Birth
Jeong A Rho, Young Il Rho, Kyung Rye Moon, Young Bong Park, Sang Kee Park, Eun Young Kim
Clin Exp Pediatr. 2003;46(10):1044-1046.   Published online October 15, 2003
Craniofrontonasal dysplasia(CFND), a rare congenital syndrome, is characterized by varying degrees of frontonasal dysplasia, craniosynostosis, and variable extracranial abnormalities. It was first reported by Cohen in 1979. The inheritance pattern is not straightforward. Although all modes of Mendelian inheritance have been suggested, the most plausible explanation is that this is an X-linked condition with the unusual situation of complete expression...
Original Article
Relationship between Admission and Clinical Features of Children Who Visited the Emergency Department with Seizures
Sung Kwan Yoon, Eun Young Kim, Eun Seok Yang, Kyung Rye Moon, Sang Kee Park, Young Bong Park, Young Il Rho, Soo Hyeong Cho
Clin Exp Pediatr. 2003;46(10):1003-1007.   Published online October 15, 2003
Purpose : To review the seizure-related complaints and analyze the relationship between admission rates and clinical features in children who had visited the emergency department with seizures. Methods : Retrospectively, we reviewed 180 patients(male 100, female 80) suffering from seizures, who had visited to the emergency department of Chosun University Hospital from January 2000 to June 2002. We have analyzed the...
Case Report
A Case of Congenital Chloride Diarrhea in Premature Infant
Sung Kwan Yoon, Eun Young Kim, Kyung Rye Moon, Sang Kee Park
Clin Exp Pediatr. 2003;46(3):308-311.   Published online March 15, 2003
Congenital chloride diarrhea is a serious autosomal recessive disease, and defect of intestinal electrolyte absorption that involves, specifically, Cl-/HCO3- exchange in the distal part of the ileum and colon. The clinical feature is dominated by profuse, watery diarrhea containing high concentrations of chloride(>90 mmol/L) and sodium. The chloride loss results in severe dehydration with a hypochloremic alkalosis. The molecular pathology...
Original Article
Analysis of Affecting Factors for Cortisol Level in Cord Blood
Hyun Jung Lim, Chang Hun Song, Eun Young Kim, Sang Kee Park
Clin Exp Pediatr. 2003;46(2):183-187.   Published online February 15, 2003
Purpose : Long-term stress to the fetus causes alterations in adrenal steroidogenesis. The purpose of this study was to analyze the association of cord blood cortisol with stress during delivery. Methods : Cord blood samples were collected from 58 neonates at once to labor. Cortisol was measured by RIA method(DPC, USA). Cortisol level according to gestational age(<34, 34-37, >38 wks)...
A Study on the Status of Utilization and Criteria for Selection of Medical Care Facilities of Elementary School Children
Seung Pyo Han, Eun Young Kim, Young Il Rho, Eun Seok Yang, Sang Kee Park, Yeong Bong Park, Kyung Rye Moon
Clin Exp Pediatr. 2002;45(2):166-173.   Published online February 15, 2002
Purpose : The aim of this study is to find out the distribution of illness, patterns of medical care utilization and factors determining medical care utilization in elementary school children. Methods : We performed the questionnaires in Gwangju city on 2,036 children of two elementary schools from June 1 to June 30, 1998. Results : The prevalence rate of illness was 32.3%....
The Clinical and Prognostic Survey of The Preterm Infants Delivered from Pregnancy-induced Hypertension Mothers
Seoung Pyo Han, Sang Kee Park, Chang Hoon Song, Jong Park, Kyoung Sim Kim, Young Youn Choi
Clin Exp Pediatr. 2002;45(1):64-71.   Published online January 15, 2002
Purpose : This study was undertaken to review the clinical and hematologic findings of the preterm infants delivered from pregnancy induced hypertension(PIH) mothers. Methods : The data were collected by reviewing the medical records on the current prognosis of preterm birth and sending questionnaires on the status of NICU. We reviewed the medical records from two university hospitals and two resident training hospitals in...
The Relationship Between Obesity and Depressive Trends in Elementary School Children
Seon Mi Park, Eun Young Kim, Young Il Rho, Sang Kee Park, Yeong Bong Park, Kyung Rye Moon, Kyung Sik Pyo
Clin Exp Pediatr. 2002;45(1):10-15.   Published online January 15, 2002
Purpose : This study was designed to evaluate the relationship between obesity and depressive trends in elementary school children. Methods : In 1999, we surveyed 2,091 elementary school children(1,079 boys and 1,012 girls) whose ages ranged from 10 to 12 years. Obesity was defined as an obesity index over 20 percent. The degree of depression was compared between the obese group...
Six Year Follow-up of Childhood Obesity
Eun Young Kim, Young Il Rho, Eun Seok Yang, Sang Kee Park, Yeung Bong Park, Kyung Rye Moon, Chul Gab Lee
Clin Exp Pediatr. 2001;44(11):1295-1300.   Published online November 15, 2001
Purpose : To examine the prevalence of obesity in elementary school-aged children in Gwangju, and long term courses of those obese children. Methods : We examined children aged 7 to 12 in the total number of 3,028 elementary school students consisting of 1,579 boys and 1,449 girls between 1994 and 1999. Obesity was defined as weight that exceeded the standard weight...
The Relationship of Maternal Disorder with Neonatal Cord Blood Leptin - Preeclampsia, Diabetes Mellitus, Antenatal Steroid Treatment -
Seon Mi Park, Eun Young Kim, Yeong Bong Park, Sang Kee Park
Clin Exp Pediatr. 2001;44(10):1119-1126.   Published online October 15, 2001
Purpose : Leptin, the product of the ob gene is primarily by adipose tissue but also by the human placenta. Leptin may also have a role as a regulator of fetal growth and development during normal pregnancy as well as in pregnancies associated with anomalous fetal growth. Our study aimed to discover whether or not leptin concentration in neonatal cord...
Prevalence and Epidemiologic Charicteristics of Chronic Recurrent Headache in Primary School Children
Young-Il Rho, Young-Bong Park, Eun Seok Yang, Sang Kee Park, Eun Youngn Kim, Jong Park, Kyung-Rye Moon
Clin Exp Pediatr. 2001;44(2):119-126.   Published online February 15, 2001
Purpose : The purpose of the study was to determine the prevalence of chronic recurrent headache and the factors associated with it among primary school children. Methods : The survey was performed by a special questionnaire on one thousand and eleven children in grades 4 to 6 at primary schools from 1 to 30 June 1999 in Gwangju city. Results : Prevalence...
Case Report
A Case of Congenital Epulis of the Newborn
Dong Gon Lee, Eun Young Kim, Sang Kee Park, eong Ryoul Yang, Dong Chool Kim, Jae Hong Seo
Clin Exp Pediatr. 2000;43(12):1621-1625.   Published online December 15, 2000
Congenital epulis of the newborn refers to a very rare gingival tumor that occurs along the anterior alveolar ridge in newborn infants. We report a neonate with 3¡¿2¡¿1.5cm mass protruding from the mouth. This was a pinky, red solid pedunculated mass, attached to the maxillar left canine region of the alveolus at birth. The tumor's large size partially obliterated the...
A Case of Catel Manzke Syndrome
Sang Hyun Oh, Eun Young Kim, Young Bong Park, Sang Kee Park, Jeong Ryoul Yang
Clin Exp Pediatr. 1999;42(8):1154-1158.   Published online August 15, 1999
Catel Manzke syndrome is characterized by hyperphalangy of the index fingers associated with Robin malformation sequence. The etiology of Catel Manzke syndrome is still uncertain, with the majority of cases being sporadic. Careful observation to recognize upper airway obstruction secondary to the Robin sequence should be made a part of routine care for newborns with this disorder. Failure to thrive...
Original Article
Erythropoietin Levels in Premature Infants Following Prolonged Treatment with Theophylline
Kug Hwan Kim, Eun Seok Yang, Sang Kee Park
Clin Exp Pediatr. 1997;40(9):1227-1231.   Published online September 15, 1997
Purpose : Theophylline, an adenosine antagonist commonly used in premature infants to treat apnea, has been shown to decrease erythropoietin levels in adults. We studied the effect of theophylline on serum erythropoietin levels in premature infants with apnea. Methods : Subject were 12 premature infants with apnea who were admitted to the NICU, Chosun University Hospital. The first dose of theophylline was 5mg/kg, given...
Case Report
A Case of Herpes Zoster in Premature Infant
Kug Hwan Kim, Young Il Ro, Eun Seok Yang, Kyung Rae Moon, Sang Kee Park, Byung Su Jung
Clin Exp Pediatr. 1997;40(8):1169-1172.   Published online August 15, 1997
Herpes zoster, an inflammatory human disease caused by varicella zoster virus, is characterized by papulovesicular lesions along the distribution of a sensory nerve. We experienced a herpes zoster in 23 day old premature infant. The papules were distributed on his skin corresponding to the dermatomes innervated by the left Th3-Th4. The diagnosis of herpes zoster was made with dermatomal distribution of typical skin lesions, pathologic...
Medical Lecture Course
Apnea of Prematurity
Sang Kee Park
Clin Exp Pediatr. 1996;39(3):306-312.   Published online March 15, 1996
Case Report
A Case of the Non-rhizomelic Chondrodysplasia Punctata
Son Ill Jin, Kyung Rye Moon, Sang Kee Park, Young Bong Park, Young Suk Kim
Clin Exp Pediatr. 1995;38(7):1000-1005.   Published online July 15, 1995
Chondrodysplasia punctata is a rare congenital disorder of bone, which is characterized by radiographic manifestation of punctate calcification in epiphyseal areas, preformed in cartilage. We experienced a case of the non-rhizomelic chondrodysplasia punctata in a male neonate who showed cataract, saddle nose, stippled calcification on X-ray without coronal cleft of verte-brae and rhizomelia.
A Case of Carbamazepine-Induced Toxic Epidermal Necrolysis
Gi Chan Na, Kyung Seok Kim, Eun Gyeoung Jung, Kyyng Rae Moon, Sang Kee Park, Yeoung Bong Park
Clin Exp Pediatr. 1993;36(11):1630-1634.   Published online November 15, 1993
Drug-induced toxic epidermal necrolysis (TEN) is a bullous erythematous disease that is characterized by the appearance of scaled lesions and large sheets of pilling on the skin. A case of TEN occured in a 10 month old female patient. The characteristic skin lesions of TEN developed after oral administration of carbamazepine for a partial seizure. Thig case consists of prodrome of...
Original Article
Effects of Equiseti Herba Water-heating Extract on the Kidney and liver of Rats
Yoon Jong Yoo, Eun Gyeoung Jung, Kap Seoung Kim, Kyeong Rae Moon, Sang Kee Park, Young Bong Park, Keun Hong Kee
Clin Exp Pediatr. 1993;36(9):1203-1210.   Published online September 15, 1993
The effects of Equiseti Herba water-heating extract on the kidey & liver of rats were studied in 25male Sprague-Dawley rats evenly divided into five groups, i.e., 5 rats each. The group I, which served as control and the group II, III, IV, were fed 300 mg/kg, 500mg/kg, 1000mg/kg of Eqiseti Herba water-heating extract daily for one week, respectively. The group...
Children with Delayed Speech Development
Sang Kee Park, Ho Sung Yoo, Yeong Bong Park
Clin Exp Pediatr. 1992;35(9):1236-1242.   Published online September 15, 1992
The antioxidant enzymes superoxide dismutase, catalase and glutathione peroxidase and the lipid peroxidation were assayed in erythroctyes from the cord blood of 25 fullterm newborn infants and their maternal blood abtained immediatedly after normal delivery. Superoxide dismutase and catalase activites in cor blood erythroctytes were significantly lower when compared with their mothers, but glutathione peroxidase activities were not significantly lower....
Case Report
Two Cases of Cornelia de Lange Syndrome
Yoon Jong Yoo, Ki Chan Na, Ho Seong Yoo, Sang Kee Park, Yong Bong Park
Clin Exp Pediatr. 1992;35(5):684-690.   Published online May 15, 1992
The Cornelia de Lange syndrome is characterized by severe growth and mental retardation, typical face, and low-pitched growling cry. We had experienced two cases of Cornelia de Lange syndrome in korean male infants. The baby showed microbrachycephaly, typical appearance of face with low forehead, bushy eyebrows, long curely eyelashs, thin lip with cleft palate, low set ears, generalized hirsutism and growth retardation...
Original Article
Inhibitory effects of several drugs to intestinal secretory stimulation of heat-labile enterotoxin produced by enterotoxigenic E. coli.
Kyung Rae Moon, Sang Kee Park, Young Wook Chun, Kap Seung Kim, Young Bong Park, Young Cheon Na, Jeong Hyung Park, Hyun Kook Lee, Nam Ung Yang
Clin Exp Pediatr. 1991;34(9):1231-1239.   Published online September 30, 1991
For exploitation of new antidiarrheal agents to heat-labile enterotoxin (LT) produced by enterotox- igenic E. coli, we have tested several drugs by rabbit ileal loop assay and obtained some significant results. L-glutathione (20 mg), P-chloromercuriphenyl sulfonic acid (20 mg) and water heating extract of Prunus mume (20 mg) reduced LT-mediated intestinal fluid secretion in rabbit ileal loop assay by 92%, 87%, 92% respectively. Maleate,...
Seroconversion rate of measles specific IgG antibody in previously vaccinated children.
Kyeoing Hun Cha, Eun Kyeong Jung, Kyung Rae Moon, Kap Seung Kim, Sang Kee Park, Yeong Bong Park
Clin Exp Pediatr. 1991;34(8):1080-1085.   Published online August 31, 1991
This study was performed to evaluate the changes of measles specific IgG antibody titer using enzyme linked immunosorbent assay (ELISA) on the sera of various groups of age. We obtained the following result: 1) Out of 118cases, 99cases (83.9%) were vaccinated children and 19cases (16.1%) were unvac- cinated children. Among them, the number of cases who had been infected with measles were 17 cases (17.2%) in...
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